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ADHD/ADD

Latest AI and machine learning research in adhd/add for healthcare professionals.

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UniProt: the Universal Protein Knowledgebase in 2025.

The aim of the UniProt Knowledgebase (UniProtKB; https://www.uniprot.org/) is to provide users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional information. In this publication, we describe ongoing changes to our production pipeline to limit the sequences available in UniProtKB to high-quality, non-redundant reference proteomes. We continu...

Jan 6 2025 39552041

Dedicated Inference Engine and Binary-Weight Neural Networks for Lightweight Instance Segmentation

Reducing computational costs is an important issue for development of embedded systems. Binary-weight Neural Networks (BNNs), in which weights are binarized and activations are quantized, are employed to reduce computational costs of various kinds of applications. In this paper, a design methodology of hardware architecture for inference engines is proposed to handle modern BNNs with two operati...

Tonotopically distinct OFF responses arise in the mouse auditory midbrain following sideband suppression

The parsing of sensory information into discrete topographic domains is a fundamental principle of sensory processing. In the auditory cortex, these d...

White matter microstructure predicts effort and reward sensitivity

From rodents to humans, animals constantly face a central question: is the reward worth the effort? Effort and reward sensitivity in such situations v...

Language network functional connectivity in infancy predicts developmental language trajectories

Although developmental language delays affect approximately 10% of children in the general population, the neurodevelopmental mechanisms that support ...

PATTY corrects open chromatin bias for improved bulk and single-cell CUT&Tag profiling

Precise profiling of epigenomes is essential for better understanding chromatin biology and gene regulation. Cleavage Under Targets & Tagmentation (CU...

Cross-Species Insights from ART-D to Uncover Evolutionarily Conserved Oncogenic Mechanisms

Cancer arises from oncogenic clones, yet the dynamic mechanisms governing their stepwise evolution toward malignancy remain incompletely understood. H...

Deep Learning of Brain-Behavior Dimensions Identifies Transdiagnostic Biotypes in Youth with ADHD and Anxiety Disorders

Attention-deficit/hyperactivity disorder and anxiety disorders are highly prevalent in youth and are characterized by substantial heterogeneity and fr...

Active Sampling and Sex Differences in Perceptual Decision Making in Rats

Decisions are typically viewed as arising from a sequential process: perception, decision, and then action. However, an alternative perspective, drawi...

Digital Twin Approaches for Interpretable Side Effect Prediction in Drug Discovery

Artificial intelligence plays an ever-greater role in preclinical drug development, ranging from target identification and molecule design to ADME-Tox...

Neural trajectories improve motor precision

Populations of neurons in motor cortex signal voluntary movement. Most classic neural encoding models and current brain-computer interface decoders as...

ADHD Medications and Preadolescent Brain Structure: Patterns of Cortical Attenuation from the ABCD Study

Attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in the U.S., and the stimulant and nonstimulant medicat...

Enigma: An Efficient Model for Deciphering Regulatory Genomics

Genomic sequence-to-function models have emerged as powerful tools for deciphering cis-regulatory grammar to advance our understanding of disease biol...

Encoding and Decoding of Brain Dynamic Functional Connectivity for ADHD Diagnosis

Recent studies have demonstrated strong associations between the changes in dynamic functional connectivity (FC) and both behavioral and cognitive fun...

How Much Does Protein Structure Really Help? A Case Study in Mutation-Induced Stability Prediction

Multimodal neural networks integrating protein language models (PLMs) with structure-derived features are increasingly common for predicting mutation ...

Multi-modal, multi-species, and multi-task latent-space model for decoding level of consciousness

Assessing the degree and characteristics of consciousness is central to caring for patients with Disorders of Consciousness (DoC), yet current standar...

MeLSI: Metric Learning for Statistical Inference in Microbiome Community Composition Analysis

Microbiome beta diversity analysis relies on distance-based methods including PERMANOVA combined with fixed ecological distance metrics (Bray-Curtis, ...

Temporal Dynamics of High-Frequency Oscillations in Alzheimer’s Disease: A Longitudinal Study in hAPP-J20 Mice

Alzheimer’s disease (AD) is characterized by progressive cognitive decline and increased seizure susceptibility; yet both the mechanistic and temporal...

Enhancing Brain Age Estimation Under Uncertainty: A Spectral-normalized Neural Gaussian Process Approach Utilizing 2.5D Slicing

Brain age gap, the difference between estimated brain age and chronological age via magnetic resonance imaging, has emerged as a pivotal biomarker in ...

Tumor-infiltrating lymphocytes in breast cancer through artificial intelligence: biomarker analysis from the results of the TIGER challenge

The prognostic significance of tumor-infiltrating lymphocytes (TILs) in breast cancer has been recognized for over a decade. Although histology-based ...

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