Allergy & Immunology

Latest AI and machine learning research in allergy & immunology for healthcare professionals.

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Immune Activation Modulation via Magnetically Localized Bacteria Based Micro/Bio Robot (BBMBR).

Understanding tumor's microenvironment is one of the key factors in the cancer therapy. Especially, from the perspective of immunotherapy, immune desert or cold tumor is referred as significantly downregulated T cell in-filtration due to lack of immune surveillance in the tumor microenvironment. There are many studies are dedicated to convert cold tumor to hot tumor for enhancing the efficacy of i...

Jul 1 2023 38082869

Handling Class Imbalance in Machine Learning-based Prediction Models: A Case Study in Asthma Management.

A data-driven prediction tool has the potential to provide early warning of an asthma attack and improve asthma management and outcomes. Most previous machine learning (ML)-based studies for asthma attack prediction have reported a severe class imbalance, with major implications for model performance. We aimed to undertake a systematic comparison of several class imbalance handling techniques in t...

Jul 1 2023 38083129
Chylous Ascites After Robot-Assisted Laparoscopic Donor Nephrectomy: Is Early Surgical Intervention Necessary?

OBJECTIVES: Chylous ascites is a rare complication that may occur after living donor nephrectomy. The continuous loss of lymphatics, which carries a h...

May 1 2023 37334687
Identifying B-cell epitopes using AlphaFold2 predicted structures and pretrained language model.

MOTIVATION: Identifying the B-cell epitopes is an essential step for guiding rational vaccine development and immunotherapies. Since experimental appr...

Apr 3 2023 37039829
Improving Methods of Identifying Anaphylaxis for Medical Product Safety Surveillance Using Natural Language Processing and Machine Learning.

We sought to determine whether machine learning and natural language processing (NLP) applied to electronic medical records could improve performance ...

Feb 1 2023 36331289
[Eight mm Port-Site Hernia Following Robot-Assisted Abdominoperineal Resection for Rectal Cancer-A Case Report].

A 70s woman with a history of asthma and dyslipidemia underwent a robot-assisted abdominoperineal resection for rectal cancer. The ports were placed a...

Feb 1 2023 36807178
Data-driven enzyme engineering to identify function-enhancing enzymes.

Identifying function-enhancing enzyme variants is a 'holy grail' challenge in protein science because it will allow researchers to expand the biocatal...

Jan 21 2023 36214500
Machine learning-based natural language processing to extract PD-L1 expression levels from clinical notes.

PD-L1 expression is used to determine oncology patients' response to and eligibility for immunologic treatments; however, PD-L1 expression status oft...

Jan 1 2023 37635280
Developments in respiratory self-management interventions over the last two decades.

This paper describes developments in the fields of asthma and COPD self-management interventions (SMIs) over the last two decades and discusses future...

Jan 1 2023 38129363
Artificial intelligence and radiomics: fundamentals, applications, and challenges in immunotherapy.

Immunotherapy offers the potential for durable clinical benefit but calls into question the association between tumor size and outcome that currently ...

Sep 1 2022 36180071
Single-frame 3D lensless microscopic imaging via deep learning.

Since the pollen of different species varies in shape and size, visualizing the 3-dimensional structure of a pollen grain can aid in its characterizat...

Aug 29 2022 36242319
Utilizing Deep Learning on Limited Mobile Speech Recordings for Detection of Obstructive Pulmonary Disease.

Passive assessment of obstructive pulmonary disease has gained substantial interest over the past few years in the mobile and wearable computing commu...

Jul 1 2022 36085620
CycleDNN - A Novel Deep Neural Network Model for CETSA Feature Prediction cross Cell Lines.

Cellular Thermal Shift Assay (CETSA) has been widely used in drug discovery, cancer cell biology, immunology, etc. One of the barriers for CETSA appli...

Jul 1 2022 36085941
Substantive Interpretation of Machine Learning Solutions by the Example of Determining the Activity of the Tuberculosis Process in Individuals with Minimal Tuberculosis Residual Changes.

In this article is described an application of various machine learning (ML) methods to obtain decision rules and its interpretation to a problem of r...

Jun 29 2022 35773830
Artificial Intelligence-based Radiomics in the Era of Immuno-oncology.

The recent, rapid advances in immuno-oncology have revolutionized cancer treatment and spurred further research into tumor biology. Yet, cancer patien...

Jun 8 2022 35348765
Chest X-ray Analysis With Deep Learning-Based Software as a Triage Test for Pulmonary Tuberculosis: An Individual Patient Data Meta-Analysis of Diagnostic Accuracy.

BACKGROUND: Automated radiologic analysis using computer-aided detection software (CAD) could facilitate chest X-ray (CXR) use in tuberculosis diagnos...

Apr 28 2022 34286831
Utilizing Deep Learning to Analyze Whole Slide Images of Colonic Biopsies for Associations Between Eosinophil Density and Clinicopathologic Features in Active Ulcerative Colitis.

BACKGROUND: Eosinophils have been implicated in the pathogenesis of ulcerative colitis and have been associated with disease course and therapeutic re...

Mar 30 2022 34106256
ImmuneData: an integrated data discovery system for immunology data repositories.

UNLABELLED: To meet the increasing demand for data sharing, data reuse and meta-analysis in the immunology research community, we have developed the d...

Mar 9 2022 35262674
Comprehensive Prediction of Lipocalin Proteins Using Artificial Intelligence Strategy.

BACKGROUND: Lipocalin belongs to the calcyin family, and its sequence length is generally between 165 and 200 residues. They are mainly stable and mul...

Mar 5 2022 35345316
epitope3D: a machine learning method for conformational B-cell epitope prediction.

The ability to identify antigenic determinants of pathogens, or epitopes, is fundamental to guide rational vaccine development and immunotherapies, wh...

Jan 17 2022 34676398
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