Allergy & Immunology

A lactylation-related gene signature predicts prognosis and immunotherapy response in clear cell renal cell carcinoma based on machine learning and multi-omics analysis.

Molecular and immunological heterogeneity of eosinophilic esophagitis: Insights and subtyping.

BACKGROUND: Eosinophilic esophagitis (EoE) and its related subtypes-such as EoE-like esophagitis, ly...

Exploring the mechanism of polymorphonuclear neutrophils against sepsis based on immune model.

BACKGROUND: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to...

Mathematical modelling and analysis of human metapneumovirus transmission dynamics using neural network intelligence and optimal control.

Human metapneumovirus (hMPV) is a serious global health threat because it causes human respiratory d...

Optimization and validation of air impingement cleaning parameters for removing nonfat dry milk powder from stainless steel surfaces by machine learning.

Air impingement cleaning can remove residues from food contact surfaces without introducing moisture...

Automated auditing of emergency department documentation using large language models.

INTRODUCTION: Errors in emergency department (ED) documentation can lead to patient harm and medicol...

TRIM36 and CAMK2N2 regulate ferroptosis and antigen presentation in small cell lung cancer.

Small cell lung cancer (SCLC) is a highly aggressive tumor with poor prognosis. Ferroptosis is close...

Artificial intelligence-assisted spatial omics-based biomimetic nanoplatform for intelligent and precise intervention in the immunosuppressive core region of ovarian cancer.

Ovarian cancer (OC) ranks among the most aggressive malignancies of the female reproductive system. ...

Large-scale paired chain BCR analysis reveals antibody clonal family inference bias and enhances resolution with machine learning.

A fundamental question in immunology is how the adaptive immune system encodes antigen specificity w...

AI-Enhanced Conversational Agents for Personalized Asthma Support in People With Asthma: Factors for Engagement, Value, and Efficacy in a Cross-Sectional Survey Study.

BACKGROUND: Asthma-related deaths in the United Kingdom are the highest in Europe, and only 30% of p...

Label-Free Raman Spectral Identification of NK and NKT Cells in Immune Heterogeneous Cell Populations.

NK and NKT cells act as major effector subsets across multiple immune heterogeneous cell populations...

Integrative spatial profiling pipeline for determining TME architectures in archival clinical specimens using CmTSA superplex technology.

The tumor microenvironment (TME) comprises diverse cellular components that spatially interact to fo...

CT image-based machine learning models for predicting blood eosinophil levels in acute exacerbation of chronic obstructive pulmonary disease.

Hematologic Patterns in Differentiating DRESS From Morbilliform Drug Eruptions: A Preliminary Investigation.

Background: Drug reaction with eosinophilia and systemic symptoms (DRESS) and morbilliform drug erup...

AI might be the next stage of our natural evolution: A cancer neuroscience perspective.

Cancer neuroscience is an emerging field at the intersection of oncology, neuroscience, and immunolo...

Future Perspectives for Artificial Intelligence in Allergy: Advances in Diagnosis, Monitoring, and Personalized Care.

Artificial intelligence (AI) is significantly transforming the specialty of allergy by offering nove...

GOLD 2026: Transforming COPD Management with Early Intervention, Multi-dimensional Assessment, and Personalized Care.

The 2026 report from the Global Initiative for Chronic Obstructive Lung Disease (GOLD) introduces su...

AGPAT3 reshapes tumor cell vulnerability to IFNγ-mediated ferroptosis and enhances immunotherapy efficacy through lipid remodeling.

BACKGROUND: Ferroptosis plays a critical role in immune regulation and tumor microenvironment remode...

Precision immunotherapies for systemic lupus erythematosus: From pathogenic targets to translational horizons.

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disorder in which aberrant B-cell a...

Effects of Environmental Factors on Incidence of Allergic Rhinitis and Chronic Rhinosinusitis: A Comparative Study.

OBJECTIVE: To investigate the associations of air pollutants and meteorological factors with outpati...

Evaluation of kidney biological age based on IgG N-glycosylation profiles and its association with chronic kidney disease in the context of predictive, preventive and personalized medicine.

BACKGROUND: Chronic kidney disease (CKD) is associated with premature aging, which reflects in the d...