Allergy & Immunology

Latest AI and machine learning research in allergy & immunology for healthcare professionals.

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Showing 701-720 of 6,930 articles

Machine learning-based integration develops a lactate metabolism related gene signature for improving outcomes in pancreatic ductal adenocarcinoma.

OBJECTIVES: Given its high global mortality rate, pancreatic ductal adenocarcinoma (PDAC) remains a significant area of investigation. However, a robust gene signature linked to lactate metabolism for PDAC patients has not yet been established. Our objective was therefore to construct a novel lactate metabolism related gene signature (LMRGS) capable of predicting patient outcomes and informing the...

Oct 28 2025 41161133

CSF1R and macrophage infiltration: Integrated magnetic resonance imaging radiomics and deep learning-driven models for the preoperative assessment of glioma.

BACKGROUND: Colony-stimulating factor-1 receptor (CSF1R) signaling is crucial for the ability of tumor-associated macrophages (TAMs) to establish an immunosuppressive tumor microenvironment (TME), highlighting the potential of CSF1R signaling as a therapeutic target. Noninvasive preoperative prediction of CSF1R levels in gliomas using magnetic resonance imaging (MRI) holds clinical potential for g...

Oct 27 2025 41146428
Screening for depression risk in asthma patients: Development and external validation of a machine learning-based predictive model.

BACKGROUND: Depression is prevalent among asthma patients, negatively impacting their quality of life, treatment adherence, and prognosis. This study ...

Oct 26 2025 41151724
Body composition radiomics combined with machine learning for early recurrence prediction in intrahepatic cholangiocarcinoma following curative surgery: A Multi-Center study.

PURPOSE: Early recurrence (ER) of intrahepatic cholangiocarcinoma (ICC) after curative hepatectomy correlates with dismal prognosis. We hypothesized t...

Oct 24 2025 41134320
Multi-omics and machine learning framework reveals ABCG2 as a therapeutic target of Eleven Flavored Shenqi Tablets in clear cell renal cell carcinoma.

ETHNOPHARMACOLOGICAL RELEVANCE: Eleven Flavored Shenqi Tablets (EFST) is a classical multi-herbal prescription in traditional Chinese medicine, tradit...

Oct 22 2025 41135615
Anxiety Promotes Occlusal Interference-Induced Myalgia via the Mesolimbic System.

Acute occlusal interference may induce chronic masticatory myalgia in some individuals. The potential factors and underlying mechanisms that predispos...

Oct 16 2025 41103016
GPT-4o in Nutrition for Inpatients Undergoing Post-Stroke Rehabilitation: Identifying Dietary Errors, Exploring Expert-AI Rationale Differences, and Structuring AI-Expert Collaboration.

OBJECTIVE: Inpatients undergoing stroke rehabilitation experience high malnutrition rates, requiring strict dietary management. However, manual and ti...

Oct 15 2025 41091021
Breaking the bottleneck of asthma treatment: the future of omni-targeted therapy.

BACKGROUND: Bronchial asthma is a complex, highly heterogeneous disease involving multiple pathological mechanisms and inflammatory pathways. Traditio...

Oct 12 2025 41086983
Genomic and Transcriptomic Profiling of High-risk Bladder Cancer Reveals Diverse Molecular and Microenvironment Ecosystems.

BACKGROUND AND OBJECTIVE: High-risk bladder cancer recurs in 30% of cases and causes fatal outcomes in 10% within 2 yr despite surgical resection, end...

Oct 7 2025 41058365
Artificial intelligence-based pollen classification machine in apiculture: design, implementation and evaluation.

BACKGROUND: Bee pollen is a bioactive substance valued for its nutritional and health-promoting properties. However, consistent quality control and cl...

Oct 6 2025 41051118
Probiotics, psychobiotics, and postbiotics: a therapeutic modality for the management of schizophrenia.

Schizophrenia is a debilitating, chronic neuropsychiatric disorder, a multifactorial disorder combining genetic, neurodevelopmental, immunological, an...

Oct 1 2025 41032844
Honey bee nutritranscriptomics reveals key insights towards precision nutrition.

INTRODUCTION: Honey bees are essential managed pollinators faced by nutritional deficiencies which contributes to worldwide colony losses. The integra...

Sep 30 2025 41038510
Machine Learning Model for an App-Based Tool to Assist With the Diagnosis of Canine Atopic Dermatitis.

BACKGROUND: Canine atopic dermatitis (cAD) is a chronic condition requiring life-long management. Accurate diagnosis can be challenging, with no relia...

Sep 29 2025 41017532
Label-free, machine-learning assisted impedance assessment of basophil activation.

Food allergies are increasing in prevalence, yet current diagnostic tests remain either inaccurate or potentially unsafe. The basophil activation test...

Sep 29 2025 41306684
Nivolumab plus ipilimumab for potentially resectable hepatocellular carcinoma: Long-term efficacy and biomarker exploration.

BACKGROUND & AIMS: Immune checkpoint inhibitor-based combination therapy has demonstrated high objective response rates in patients with hepatocellula...

Sep 17 2025 40972843
A Metabolism-Driven Prognostic Model and PSMD14-SP1-GYS1 Axis Reveal Therapeutic Vulnerabilities in Melanoma.

Melanoma is a highly aggressive cutaneous malignancy characterized by a strong propensity for metastasis and therapy resistance, with its progression ...

Sep 16 2025 40967300
Salt-inducible kinase 1 is a key gene in suppressing EVD68-induced asthma by modulating antiviral immunity.

Asthma is a complex inflammatory disease of the airways, affecting over 300 million individuals globally. Infection with enterovirus D68 (EV-D68) has ...

Sep 10 2025 41674661
Machine learning in allergy research: A bibliometric review.

The emergence of big data and analytic approaches initiated research efforts to characterise different subtypes of allergic diseases, including tracki...

Sep 8 2025 40930256
Harnessing biomarkers to guide immunotherapy in esophageal cancer: toward precision oncology.

Esophageal cancer (EC) is one of the most serious health issues around the world, ranking seventh among the most lethal types of cancer and eleventh a...

Sep 6 2025 40914748
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