Latest AI and machine learning research in allergy & immunology for healthcare professionals.
High-dimensional flow cytometry provides rich immunological data for examining immune responses and their relationships with disease pathology, but its complexity, heterogeneity, high-dimensionality, and modest sample sizes limit translation into clinical applications. We describe a translational immune health framework that applies supervised learning algorithms to integrate high-dimensional cell...
Immunotherapy has revolutionized cancer treatment, yet substantial inter-patient response heterogeneity limits therapeutic benefit to specific patient subsets. Here, we present PathTIGR, a pathway topology-informed graph representation learning framework that systematically integrates biological pathway network topology knowledge with genome variation information for immunotherapy response predict...
Lipid transfer proteins (LTPs) are clinically relevant allergens widely present in plant-based foods, and their reliable detection in complex food mat...
BACKGROUND: Chronic dermatologic conditions such as psoriasis, atopic dermatitis, and hidradenitis suppurativa are associated with a high burden of ps...
BACKGROUND: Most patients with biliary tract cancer (BTC) do not derive durable clinical benefit (DCB) from immune checkpoint inhibitors (ICIs), under...
Colorectal cancer stem-like cells (CRC-SCs) represent a tumor subpopulation with enhanced tumor-initiating capacity and have been implicated in metast...
BACKGROUND: Myofascial pain syndrome (MPS) is considered highly prevalent in horses, yet it is frequently underdiagnosed due to limited understanding ...
Food allergies affect over 220 million individuals worldwide and present increasing challenges due to complex food matrices and processing-induced pro...
Autism Spectrum Disorder (ASD) arises from complex and not yet completely understood interactions between genetic and environmental factors. Alongside...
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that is manifested by sensory abnormalities such as hypersensitivity to sound and touc...
Acute lung injury (ALI) is a significant post-operative complication of liver transplant (LT), with mounting evidence suggesting a role for the gut-lu...
BACKGROUND: Systemic lupus erythematosus (SLE) is a complex, fluctuating disease, creating a continuous need for reliable patient information. A prior...
BACKGROUND: Fruit juice quality is regulated by European Union legislation; however, adulteration by adding cheaper alternatives, such as white grape ...
BACKGROUND: The epigenetic control of immune responses plays a crucial role in the development and progression of cancer. The need to identify biomark...
BACKGROUND: The introduction of neoadjuvant and perioperative immunotherapy has broadened treatment options for resectable non-small cell lung cancer ...
We discuss how graph-based machine learning (Graph ML) can guide discovery in the next era of systems immunology. The multi-scale complexity of the im...
BACKGROUND: Breast cancer (BC) is the most common cancer in women and the leading cause of cancer-related death worldwide. Systemic immune dysregulati...
Glioblastoma multiforme (GBM) is the most common and aggressive primary malignant brain tumor. Despite combined treatments, including surgical removal...
Rapid profiling of an unexpected blood group antibody spectrum plays a critical role in emergency medicine. However, field-deployable profiling still ...
OBJECTIVES: Pediatric asthma exacerbations are a common emergent condition treated by prehospital emergency medical services (EMS). However, retrospec...