Allergy & Immunology

Allergy

Latest AI and machine learning research in allergy for healthcare professionals.

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Showing 601-620 of 11,055 articles

Machine Learning Model for an App-Based Tool to Assist With the Diagnosis of Canine Atopic Dermatitis.

BACKGROUND: Canine atopic dermatitis (cAD) is a chronic condition requiring life-long management. Accurate diagnosis can be challenging, with no reliable diagnostic test. OBJECTIVES: This study aimed to generate a simple diagnostic model for cAD. MATERIALS AND METHODS: Machine learning by Random Forest was applied to metadata from a prospective dataset of clinical cases definitively diagnosed with...

Sep 29 2025 41017532

Label-free, machine-learning assisted impedance assessment of basophil activation.

Food allergies are increasing in prevalence, yet current diagnostic tests remain either inaccurate or potentially unsafe. The basophil activation test (BAT) has emerged as a promising functional assay, involving the ex vivo stimulation of whole blood with allergens and subsequent measurement of basophil activation. The BAT has been shown to have high diagnostic accuracy. However, clinical adoption...

Sep 29 2025 41306684
Nivolumab plus ipilimumab for potentially resectable hepatocellular carcinoma: Long-term efficacy and biomarker exploration.

BACKGROUND & AIMS: Immune checkpoint inhibitor-based combination therapy has demonstrated high objective response rates in patients with hepatocellula...

Sep 17 2025 40972843
A Metabolism-Driven Prognostic Model and PSMD14-SP1-GYS1 Axis Reveal Therapeutic Vulnerabilities in Melanoma.

Melanoma is a highly aggressive cutaneous malignancy characterized by a strong propensity for metastasis and therapy resistance, with its progression ...

Sep 16 2025 40967300
Machine learning in allergy research: A bibliometric review.

The emergence of big data and analytic approaches initiated research efforts to characterise different subtypes of allergic diseases, including tracki...

Sep 8 2025 40930256
Harnessing biomarkers to guide immunotherapy in esophageal cancer: toward precision oncology.

Esophageal cancer (EC) is one of the most serious health issues around the world, ranking seventh among the most lethal types of cancer and eleventh a...

Sep 6 2025 40914748
LYnet: Computational identification of tumor T cell antigens using convolutional and recurrent neural networks.

BACKGROUND: Immunotherapy represents a paradigm shift in oncology, offering advantages in efficacy and specificity over traditional therapies. Key to ...

Aug 19 2025 40876398
Selenium biofortification: integrating one health and sustainability.

Selenium (Se) biofortification in crops has emerged as a promising strategy to address global Se deficiencies and enhance both agricultural productivi...

Aug 2 2025 40751944
A machine learning-driven transcriptomic study reveals the key role of Romo1 in reversing central sensitization through stellate ganglion block in migraine: An interventional study based on a recurrent migraine rat model.

OBJECTIVES/BACKGROUND: This study utilized a nitroglycerin (NTG)-induced chronic migraine rat model to explore the therapeutic effects and underlying ...

Aug 1 2025 40747904
A machine learning platform for genotype-specific cardiotoxicity risk prediction using patient-derived iPSC-CMs.

INTRODUCTION: Drug-induced Torsades de Pointes (TdP) has led to withdrawal of several drugs from the market. Individuals with inherited cardiac channe...

Jul 22 2025 40706985
AI Prognostication in Nonsmall Cell Lung Cancer: A Systematic Review.

The systematic literature review was performed on the use of artificial intelligence (AI) algorithms in nonsmall cell lung cancer (NSCLC) prognosticat...

Jul 18 2025 40679809
Can a Rule-Based Expert System Diagnose Nasal Obstruction from Nasoendoscopy Videos?

Nasal obstruction has multiple causes requiring specialist endoscopy for diagnosis. A rule-based expert system (RB-ES), which applies five "if-then" r...

Jul 16 2025 40669854
iALP: Identification of Allergenic Proteins Based on Large Language Model and Gate Linear Unit.

The rising incidence of allergic disorders has emerged as a pressing public health issue worldwide, underscoring the need for intensified research and...

Jul 13 2025 40652417
Integrative analysis of multi-omics data and gut microbiota composition reveals prognostic subtypes and predicts immunotherapy response in colorectal cancer using machine learning.

Colorectal cancer (CRC) exhibits substantial heterogeneity in molecular subtypes and clinical outcomes. We performed an integrative analysis of multi-...

Jul 12 2025 40652009
Development and validation of a prognostic model for predicting survival and immunotherapy benefits in melanoma based on metabolism-relevant genes.

Skin cutaneous melanoma (SKCM) is a fatal form of skin cancer. Metabolism-related genes (MRGs) comprise a group of genes that possess the ability to m...

Jul 12 2025 40652057
Single-cell spatial transcriptomics reveals immunotherapy-driven bone marrow niche remodeling in AML.

Given the graft-versus-leukemia effect observed with allogeneic hematopoietic stem cell transplantation in refractory or relapsed acute myeloid leukem...

Jul 9 2025 40632867
Computation strategies and clinical applications in neoantigen discovery towards precision cancer immunotherapy.

Neoantigens, which are tumor-specific peptides generated by malignant cells, can be presented to T cells to elicit immune responses. Owing to their tu...

Jul 9 2025 40629481
Leveraging machine learning models to evaluate immune infiltration in the ovarian cancer microenvironment: a single-cell analysis approach.

BACKGROUND: The prognosis of ovarian cancer is closely related to the degree of immune cell infiltration within the tumor microenvironment. However, c...

Jul 9 2025 40632369
Analysis of Single-Cell RNA-Seq Data to Investigate Tumor Cell Heterogeneity in Uroepithelial Bladder Cancer and Predict Immunotherapy Response.

BACKGROUND: Numerous studies have suggested a close association between cancer stem cells (CSCs) and the tumor microenvironment (TME), suggesting that...

Jul 8 2025 40635219
Metabolic alterations driven by LDHA in CD8 + T cells promote immune evasion and therapy resistance in NSCLC.

Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related deaths worldwide. Despite advancements in treatment, prognosis for patients wi...

Jul 8 2025 40629035
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