Geriatrics

Alzheimer's Disease

Latest AI and machine learning research in alzheimer's disease for healthcare professionals.

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Geriatrics Subcategories: Alzheimer's Disease Medicare
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Generative artificial intelligence, integrative bioinformatics, and single-cell analysis reveal Alzheimer's genetic and immune landscape.

The research aims to understand Alzheimer's genetic and immune landscapes using the amalgamation of three technologies: artificial intelligence (GenAI), integrative bioinformatics, and single-cell analysis. First, the study aims to identify and characterize the significant genes associated with Alzheimer's disease (AD) using three GenAI models (GPT‑4o, Gemini model, and DeepSeek). After the genes ...

Apr 24 2025 40496817

Enhanced EEG-based Alzheimer's disease detection using synchrosqueezing transform and deep transfer learning.

The most prevalent type of dementia and a progressive neurodegenerative disease, Alzheimer's disease has a major influence on day-to-day functioning due to memory loss, cognitive decline, and behavioral problems. By using synchrosqueezing representations of EEG signals classified by fine-tuned pre-trained convolutional neural networks, this paper presents an EEG-based classification model for Alzh...

Apr 24 2025 40286903
A review of multimodal fusion-based deep learning for Alzheimer's disease.

Alzheimer's Disease (AD) as one of the most prevalent neurodegenerative disorders worldwide, characterized by significant memory and cognitive decline...

Apr 24 2025 40286904
Cerebrospinal fluid inflammatory cytokines as prognostic indicators for cognitive decline across Alzheimer's disease spectrum.

BackgroundNeuroinflammation actively contributes to the pathophysiology of Alzheimer's disease (AD); however, the value of neuroinflammatory biomarker...

Apr 22 2025 40262111
The clinical significance of an AI-based assumption model for neurocognitive diseases using a novel dual-task system.

Dual-task composed of gait or stepping tasks combined with cognitive tasks has been well-established as valuable tools for detecting neurocognitive di...

Apr 22 2025 40263361
Revolutionizing Alzheimer's disease detection with a cutting-edge CAPCBAM deep learning framework.

Early and accurate diagnosis of Alzheimer's disease (AD) is crucial for effective treatment. While the integration of deep learning techniques for AD ...

Apr 22 2025 40263406
A Multimodal Approach for Early Identification of Mild Cognitive Impairment and Alzheimer's Disease With Fusion Network Using Eye Movements and Speech.

Detecting Alzheimer's disease (AD) in its earliest stages, particularly during an onset of Mild Cognitive Impairment (MCI), remains challenging due to...

Apr 22 2025 40232896
Social robot PIO intervention for improving cognitive function and depression in older adults with mild to moderate dementia in day care centers: A randomized controlled trial.

The increases in the older population, the prevalence of dementia, and the resulting social costs are burdensome to individuals, families, and the nat...

Apr 22 2025 40261884
Alzheimer's Disease Dementia Prevalence in the United States: A County-Level Spatial Machine Learning Analysis.

A growing body of literature has examined the impact of neighborhood characteristics on Alzheimer's disease (AD) dementia, yet the spatial variability...

Apr 21 2025 40257111
Computational modelling for risk assessment of neurological disorder in diabetes using Hodgkin-Huxley model.

BACKGROUND: Diabetes mellitus, characterized by chronic glucose dysregulation, significantly increases the risk of neurological disorders such as cogn...

Apr 20 2025 40287992
Transcriptomic analyses of human brains with Alzheimer's disease identified dysregulated epilepsy-causing genes.

BACKGROUND & OBJECTIVE: Alzheimer's Disease (AD) patients at multiple stages of disease progression have a high prevalence of seizures. However, wheth...

Apr 17 2025 40250147
c-Triadem: A constrained, explainable deep learning model to identify novel biomarkers in Alzheimer's disease.

Alzheimer's disease (AD) is a neurodegenerative disorder that requires early diagnosis for effective management. However, issues with currently availa...

Apr 14 2025 40228177
Hybrid of DSR-GAN and CNN for Alzheimer disease detection based on MRI images.

In this paper, we propose a deep super-resolution generative adversarial network (DSR-GAN) combined with a convolutional neural network (CNN) model de...

Apr 13 2025 40222973
IT: An interpretable transformer model for Alzheimer's disease prediction based on PET/MR images.

Alzheimer's disease (AD) represents a significant challenge due to its progressive neurodegenerative impact, particularly within an aging global demog...

Apr 11 2025 40222500
Exploring the perceptions and experiences of caregivers with the application of socially assistive robots in dementia care: A systematic review of qualitative studies.

BACKGROUND: The use of socially assistive robots in dementia care is growing, aimed at improving patient well-being and alleviating caregiver burden. ...

Apr 10 2025 40262375
CLIC1 and IFITM2 expression in brain tissue correlates with cognitive impairment via immune dysregulation in sepsis and Alzheimer's disease.

BACKGROUND: Sepsis, a life-threatening condition driven by dysregulated host responses to infection, is associated with long-term cognitive impairment...

Apr 10 2025 40215772
Assessing the cardioprotective effects of exercise in APOE mouse models using deep learning and photon-counting micro-CT.

BACKGROUND: The allelic variations of the apolipoprotein E (APOE) gene play a critical role in regulating lipid metabolism and significantly impact ca...

Apr 10 2025 40208877
The Cognivue Amyloid Risk Measure (CARM): A Novel Method to Predict the Presence of Amyloid with Cognivue Clarity.

INTRODUCTION: At the present time, clinical detection of individuals who have amyloid in their brain is not possible without expensive biomarkers. The...

Apr 7 2025 40192926
Ensemble deep learning for Alzheimer's disease diagnosis using MRI: Integrating features from VGG16, MobileNet, and InceptionResNetV2 models.

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid plaques and neurofibrillary tangles in the brain...

Apr 7 2025 40193955
The impact of Alzheimer's disease on cortical complexity and its underlying biological mechanisms.

BACKGROUND: Alzheimer's disease (AD) might impact the complexity of cerebral cortex, and the underlying biological mechanisms responsible for cortical...

Apr 4 2025 40189107
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