Alzheimer's Disease

Ethical issues when using digital biomarkers and artificial intelligence for the early detection of dementia.

Dementia poses a growing challenge for health services but remains stigmatized and under-recognized. Digital technologies to aid the earlier detection of dementia are approaching market. These include traditional cognitive screening tools presented on mobile devices, smartphone native applications, passive data collection from wearable, in-home and in-car sensors, as well as machine learning techn...

An attention-based deep learning approach for the classification of subjective cognitive decline and mild cognitive impairment using resting-state EEG.

. This study aims to design and implement the first deep learning (DL) model to classify subjects in the prodromic states of Alzheimer's disease (AD) based on resting-state electroencephalographic (EEG) signals.. EEG recordings of 17 healthy controls (HCs), 56 subjective cognitive decline (SCD) and 45 mild cognitive impairment (MCI) subjects were acquired at resting state. After preprocessing, we ...

Nurses' perception towards care robots and their work experience with socially assistive technology during COVID-19: A qualitative study.

This study aimed to explore nurses' perceptions towards care robots and their work experiences in caring for older adults who use socially assistive t...

Interpretable machine learning for dementia: A systematic review.

INTRODUCTION: Machine learning research into automated dementia diagnosis is becoming increasingly popular but so far has had limited clinical impact....

Convolution Neural Networks and Self-Attention Learners for Alzheimer Dementia Diagnosis from Brain MRI.

Alzheimer's disease (AD) is the most common form of dementia. Computer-aided diagnosis (CAD) can help in the early detection of associated cognitive i...

SynthSR: A public AI tool to turn heterogeneous clinical brain scans into high-resolution T1-weighted images for 3D morphometry.

Every year, millions of brain magnetic resonance imaging (MRI) scans are acquired in hospitals across the world. These have the potential to revolutio...

Do artificial neural networks love sex? How the combination of artificial neural networks with evolutionary algorithms may help to identify gender influence in rheumatic diseases.

Although medical research has been performed predominantly on men both in preclinical and clinical studies, continuous efforts have been made to overc...

Precise Discrimination for Multiple Etiologies of Dementia Cases Based on Deep Learning with Electroencephalography.

INTRODUCTION: It is critical to develop accurate and universally available biomarkers for dementia diseases to appropriately deal with the dementia pr...

[Artificial intelligence and ethics in healthcare-balancing act or symbiosis?].

Artificial intelligence (AI) is becoming increasingly important in healthcare. This development triggers serious concerns that can be summarized by si...

A machine-learning algorithm for predicting brain age using Rey-Osterrieth complex figure tests of healthy participants.

OBJECTIVE: Neuropsychologists widely use the Rey-Osterrieth complex figure test (RCFT) as part of neuropsychological test batteries to evaluate cognit...

Identification of Glucose Transport Modulators In Vitro and Method for Their Deep Learning Neural Network Behavioral Evaluation in Glucose Transporter 1-Deficient Mice.

Metabolic flux augmentation via glucose transport activation may be desirable in glucose transporter 1 (Glut1) deficiency syndrome (G1D) and dementia,...

Anatomically interpretable deep learning of brain age captures domain-specific cognitive impairment.

The gap between chronological age (CA) and biological brain age, as estimated from magnetic resonance images (MRIs), reflects how individual patterns ...

Towards better interpretable and generalizable AD detection using collective artificial intelligence.

Alzheimer's Disease is the most common cause of dementia. Accurate diagnosis and prognosis of this disease are essential to design an appropriate trea...

Application of machine learning techniques for dementia severity prediction from psychometric tests in the elderly population.

Previous research has shown the benefits of early detection and treatment of dementia. This detection is usually performed manually by one or more cli...

Deep Learning for Brain MRI Confirms Patterned Pathological Progression in Alzheimer's Disease.

Deep learning (DL) on brain magnetic resonance imaging (MRI) data has shown excellent performance in differentiating individuals with Alzheimer's dise...

Predicting Genetic Disorder and Types of Disorder Using Chain Classifier Approach.

Genetic disorders are the result of mutation in the deoxyribonucleic acid (DNA) sequence which can be developed or inherited from parents. Such mutati...

Assess the documentation of cognitive tests and biomarkers in electronic health records via natural language processing for Alzheimer's disease and related dementias.

BACKGROUND: Cognitive tests and biomarkers are the key information to assess the severity and track the progression of Alzheimer's' disease (AD) and A...

Automatic lesion detection and segmentation in F-flutemetamol positron emission tomography images using deep learning.

BACKGROUND: Beta amyloid in the brain, which was originally confirmed by post-mortem examinations, can now be confirmed in living patients using amylo...

Deep learning-based speech analysis for Alzheimer's disease detection: a literature review.

BACKGROUND: Alzheimer's disease has become one of the most common neurodegenerative diseases worldwide, which seriously affects the health of the elde...

The usability and feasibility validation of the social robot MINI in people with dementia and mild cognitive impairment; a study protocol.

BACKGROUND: Social robots have demonstrated promising outcomes in terms of increasing the social health and well-being of people with dementia and mil...