Geriatrics

Alzheimer's Disease

Latest AI and machine learning research in alzheimer's disease for healthcare professionals.

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Geriatrics Subcategories: Alzheimer's Disease Medicare
Showing 141-160 of 14,520 articles

Safety boundary maintenance in consumer AI systems responding to pediatric health queries: a cross-platform benchmark evaluation under naturalistic and adversarially pressured conditions.

Consumer artificial intelligence chatbots are now accessed by hundreds of millions of users seeking health information, yet systematic evaluation of their safety boundary maintenance under real-world caregiver pressure remains scarce. We evaluated PediatricSafetyBench-v2, a benchmark of 600 pediatric health queries comprising 300 authentic caregiver queries sourced from the HealthCareMagic-100k-en...

Jul 14 2026 42448823

Generative large language models in the clinical management of Alzheimer's disease and mild cognitive impairment.

BACKGROUND: Dementia affects over 55 million people worldwide. Mild cognitive impairment (MCI) often precedes Alzheimer's disease (AD). Clinical management requires integrating uncertain evidence from neuropsychological testing, neuroimaging, and biomarkers. Large language models (LLMs) also generate probabilistic outputs, but whether they can reliably support diagnostic, therapeutic, or education...

Jul 13 2026 42440193
Predicting drug release from polymeric long-acting injectables using a machine learning approach to decode formulation-performance relationships.

Polymeric long-acting injectables (LAIs) are among the most impactful yet least predictable drug delivery systems, as their performance emerges from a...

Jul 13 2026 42443630
Machine learning-enabled behavioural and psychological symptoms of dementia management intervention for dementia caregivers: protocol for a hybrid factorial SMART-MRT trial.

BACKGROUND: Behavioural and psychological symptoms of dementia (BPSD) affect over 90% of people living with dementia and are a major contributor to st...

Jul 13 2026 42443790
Multilayer Validation Reveals a Glia-Associated Secretome Signature in Temporal Lobe Epilepsy.

Although multi-omics studies have increasingly revealed molecular alterations associated with epilepsy, clinically accessible cerebrospinal fluid (CSF...

Jul 11 2026 42435258
Precision therapeutics and innovative clinical trial design in neurodegenerative diseases.

Neurodegenerative diseases are biologically heterogeneous disorders characterized by progressive neuronal dysfunction, overlapping molecular pathologi...

Jul 11 2026 42435587
Assessing the accuracy of ChatGPT responses to caregiver questions in pediatric neurology: an observational study.

ChatGPT has seen increased use by caregivers as a source of medical information. Pediatric neurology has added complexities because there are various ...

Jul 11 2026 42436249
Bioinformatic analysis of differentially expressed mitochondrion-related genes, immune cell infiltration, and diagnostic value in Alzheimer's disease.

BACKGROUND: Mitochondrial dysfunction and neuroinflammation are critically implicated in the pathogenesis of Alzheimer's disease (AD). However, a syst...

Jul 11 2026 42436416
SMDNet: A Self-Training-Aware and Multi-Modal-Adaptive Deep Learning Network for Low-Data Aβ42 Probe Design and Optimization.

Amyloid-β (Aβ) plaque accumulation is a crucial hallmark of Alzheimer's disease, and fluorescence imaging can support disease diagnosis and monitoring...

Jul 10 2026 42429744
Large Language Model-Assisted Annotation Framework for Cross-Platform Analysis of Online Autism Communities: Implications for Parent Education and Digital Support.

BACKGROUND: Online health communities (OHCs) are important channels for families of children with autism spectrum disorder to obtain health informatio...

Jul 10 2026 42430199
The brain structure and immunometabolic mechanisms underlying the association between frailty and dementia.

BACKGROUND: Physical frailty, characterized by heightened sensitivity to stressors and decreased physiological reserves, is an established risk factor...

Jul 10 2026 42430904
Novel approach to early prediction of alzheimer's disease progression using integrated deep regulatory genetic neural network and optimized deep belief networks.

UNLABELLED: To enhance the prediction progression of Alzheimer's Disease is very excavating process. PROBLEM STATEMENT: It is often very difficult to ...

Jul 10 2026 42431913
Transdiagnostic behavioral and sociodemographic influences on the cognitive-adaptive functioning gap in neurodivergent children.

Adaptive functioning typically aligns with cognitive ability in the general population, but this relationship appears more complex in neurodivergent p...

Jul 10 2026 42431939
An interpretable multimodal framework using compact biomarkers and Kolmogorov-Arnold networks improves the early diagnosis of Alzheimer's disease.

Early diagnosis of Alzheimer's disease (AD), especially accurate identification at the mild cognitive impairment (MCI) stage, is crucial for slowing d...

Jul 10 2026 42431966
The role of AI-assisted drug repurposing in neurological disorders: a systematic review of validation strategies, challenges and opportunities.

Neurological disorders refer to a diverse group of conditions that affect the brain, peripheral nerves, and spinal cord and impair socioemotional, cog...

Jul 10 2026 42432671
AI-Driven Digital Twin Architecture for Multimodal Prediction and Adaptive Intervention in Cognitive Aging.

Age-related cognitive dysfunction, including mild cognitive impairment and dementia, underscores the need for scalable and personalized predictive mod...

Jul 8 2026 42417454
Dietary patterns and Alzheimer's disease: East-west perspectives and future intervention strategies.

Among various modifiable risk factors, dietary patterns (DPs), as a holistic lifestyle intervention, have become a focus of current research due to th...

Jul 8 2026 42419161
Exploring the Experiences of Moderators From an Asynchronous Online Dementia Support Forum: Qualitative Interview Study.

BACKGROUND: Asynchronous online forums provide flexible, accessible peer support for many people living with dementia and carers. Moderators are centr...

Jul 7 2026 42412909
Deep Plasma Proteomics-Based Diagnostic Panel for Early Detection of Amnestic Mild Cognitive Impairment.

Amnestic mild cognitive impairment (aMCI) is often considered an early clinical stage of Alzheimer's disease (AD), but its subtle presentation leads t...

Jul 7 2026 42413022
Machine learning and mobile sensing for naturalistic infant behavior (0-36 months): A comprehensive review and research agenda.

The recent rapid development of mobile and wearable sensing technologies and computational modeling has allowed for high-density and continuous measur...

Jul 7 2026 42413280
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