Anxiety & Stress

Reverse-Phase Chromatographic Determination and Intrinsic Stability Behavior of 5-[(4-Chlorophenoxy)Methyl]-1,3,4-Oxadiazole-2-Thiol.

The study describes the development and preliminary validation of a simple reverse-phase chromatographic method for determination of a novel drug candidate, 5-[(4-chlorophenoxy) methyl]-1,3,4-oxadiazole-2-thiol (OXCPM), in bulk and stressed solution, in order to find out the intrinsic stability behavior of the compound. Isocratic elution was carried out at a flow rate of 1.0 mL min-1 through a Pro...

Automated Pain Assessment using Electrodermal Activity Data and Machine Learning.

Objective pain assessment is required for appropriate pain management in the clinical setting. However, clinical gold standard pain assessment is based on subjective methods. Automated pain detection from physiological data may provide important objective information to better standardize pain assessment. Specifically, electrodermal activity (EDA) can identify features of stress and anxiety induce...

A Multi-feature Fuzzy Index to Assess Stress Level from Bio-signals.

A mono-feature fuzzy index that evaluates the stress level from one feature extracted from ECG or GSR is presented. It is build using several measures...

A deep learning approach to estimate stress distribution: a fast and accurate surrogate of finite-element analysis.

Structural finite-element analysis (FEA) has been widely used to study the biomechanics of human tissues and organs, as well as tissue-medical device ...

In vitro assessment of the cytotoxic, DNA damaging, and cytogenetic effects of hydroquinone in human peripheral blood lymphocytes.

This study investigated the mechanisms of hydroquinone toxicity and assessed the relationships between its cytotoxic, genotoxic, and cytogenetic effec...

Cinnamic acid and fish flour affect wheat phenolic acids and flavonoid compounds, lipid peroxidation, proline levels under salt stress.

To elucidate the physiological mechanism of salt stress mitigated by cinnamic acid (CA) and fish flour (FF) pretreatment, wheat was pretreated with 20...

Effects of treatment with chemotherapy and/or tamoxifen on the biomarkers of cardiac injury and oxidative stress in women with breast cancer.

There has been an increase in deaths from cardiovascular diseases following breast cancer therapy. Evidence has shown that this outcome is, in part, a...

An artificial neural network prediction model of congenital heart disease based on risk factors: A hospital-based case-control study.

An artificial neural network (ANN) model was developed to predict the risks of congenital heart disease (CHD) in pregnant women.This hospital-based ca...

Technology for Early Detection of Depression and Anxiety in Older People.

Under-diagnosis of depression and anxiety is common in older adults. This project took a mixed methods approach to explore the application of machine ...

Comparison of Different Algorithms for Sentiment Analysis: Psychological Stress Notes.

To visualize and compare three text analysis algorithms of sentiment (AFINN, Bing, Syuzhet), applied to 1549 ecologically assessed self-report stress ...

Digital Mental Health - Innovations in Consumer Driven Care.

Barriers such as stigma and access issues prevent 60% of Canadians with mental health issues from seeking help. Saint Elizabeth Health Care's Intellig...

The Hepatoprotective Effect of Clidemia hirta against Carbon Tetrachloride (CCl4)-Induced Oxidative Stress and Hepatic Damage in Mice.

Liver diseases still represents a major health burden worldwide. Moreover, medicinal plants have gained popularity in the treatment of several disease...

Effect of cerebrolysin on oxidative stress-induced apoptosis in an experimental rat model of myocardial ischemia.

Apoptosis plays a role in the process of tissue damage after myocardial infarction (MI). This study was designed to investigate the possible effect of...

Evaluation of a Technology-Based Adaptive Learning and Prevention Program for Stress Response-A Randomized Controlled Trial.

To prevent deployment-related disorders, Chaos Driven Situations Management Retrieval System (CHARLY), a computer-aided training platform with a biofe...

Detection of mental stress due to oral academic examination via ultra-short-term HRV analysis.

Mental stress may cause cognitive dysfunctions, cardiovascular disorders and depression. Mental stress detection via short-term Heart Rate Variability...

Takotsubo stress-induced cardiomyopathy following robotic radical cystectomy.

Cardiac complications following surgery can be devastating especially if it is unrecognized. We present a case of a stress-induced cardiomyopathy that...

Brief Report: A Pilot Summer Robotics Camp to Reduce Social Anxiety and Improve Social/Vocational Skills in Adolescents with ASD.

This pilot study evaluated a novel intervention designed to reduce social anxiety and improve social/vocational skills for adolescents with autism spe...

[Effect of glutaredoxin on oxidative stress of umbilical vein endothelial cell exposed to Porphyromonas gingivalis lipo- polysaccharide].

OBJECTIVE: This study measures the glutaredoxin (Grx) gene and protein expression in umbilical vein endothelial cells upon exposure to Porphyromonas g...

Development and validation of a stability-indicating reverse phase ultra performance liquid chromatographic method for the estimation of nebivolol impurities in active pharmaceutical ingredients and pharmaceutical formulation.

A sensitive, stability-indicating gradient reverse phase ultra performance liquid chromatographic method has been developed for the quantitative estim...

Supervised machine learning algorithms to diagnose stress for vehicle drivers based on physiological sensor signals.

Machine learning algorithms play an important role in computer science research. Recent advancement in sensor data collection in clinical sciences lea...