Arthritis

Using deep-learning based segmentation to enable spatial evaluation of knee osteoarthritis (SEKO) in rodent models.

OBJECTIVE: In preclinical models of osteoarthritis (OA), histology is commonly used to evaluate join...

Deep learning reconstruction enhances tophus detection in a dual-energy CT phantom study.

This study aimed to compare two deep learning reconstruction (DLR) techniques (AiCE mild; AiCE stron...

Integrating bioinformatics and machine learning to identify biomarkers of branched chain amino acid related genes in osteoarthritis.

BACKGROUND: Branched-chain amino acids (BCAA) metabolism is significantly associated with osteoarthr...

Early prediction of bone destruction in rheumatoid arthritis through machine learning analysis of plasma metabolites.

BACKGROUND: To develop a predictive model for bone destruction in patients with rheumatoid arthritis...

Next-Level Prediction of Structural Progression in Knee Osteoarthritis: A Perspective.

Osteoarthritis (OA) is a prevalent and disabling chronic disease, with knee OA being the most common...

Clinical utility of ultrasound and MRI in rheumatoid arthritis: An expert review.

Musculoskeletal ultrasound (MSUS) and magnetic resonance imaging (MRI) are advanced imaging techniqu...

A metaheuristic optimization-based approach for accurate prediction and classification of knee osteoarthritis.

Knee osteoarthritis (KOA) is a severe arthrodial joint condition with significant global socioeconom...

Artificial Intelligence Model Assists Knee Osteoarthritis Diagnosis via Determination of K-L Grade.

Knee osteoarthritis (KOA) affects 37% of individuals aged ≥ 60 years in the national health survey,...

Biological markers and psychosocial factors predict chronic pain conditions.

Chronic pain is a multifactorial condition presenting significant diagnostic and prognostic challeng...

Lead Informed Artificial Intelligence Mining of Antitubercular Host Defense Peptides.

Identifying host defense peptides (HDPs) that are effective against drug-resistant infections is cha...

Dendritic cell-based microrobots for enhanced systemic antigen-specific immune tolerance.

Current immunotherapeutic approaches for autoimmune disorders primarily rely on the use of generaliz...

Editorial Commentary: Deteriorated Quality and Medial Retraction of Tendon Following Acute Traumatic Rotator Cuff Tear Are Predictors of Retear After Arthroscopic Repair.

Rotator cuff tears are a common cause of shoulder pain and dysfunction, affecting up to 33% of the p...

Metabolomic profiles underlying gout flares: a prospective study of people with gout.

OBJECTIVES: To identify specific metabolomic profiles associated with gout flares in people with gou...

Optimizing the dynamic treatment regime of outpatient rehabilitation in patients with knee osteoarthritis using reinforcement learning.

BACKGROUND: Knee osteoarthritis (KOA) is a prevalent chronic disease worldwide, and traditional trea...

Limitations of Machine Learning-Based Feature Importance in Osteoarthritis Biomarker Discovery.

Comparing Artificial Intelligence-Generated and Clinician-Created Personalized Self-Management Guidance for Patients With Knee Osteoarthritis: Blinded Observational Study.

BACKGROUND: Knee osteoarthritis is a prevalent, chronic musculoskeletal disorder that impairs mobili...

Analytical Quality by Design for Chiral Pharmaceuticals: A Robust HPLC Method for Upadacitinib Enantiomeric Quantification.

Ensuring the enantiomeric purity of chiral pharmaceuticals is paramount for patient safety and thera...

Deep learning image enhancement for confident diagnosis of TMJ osteoarthritis in zero-TE MR imaging.

OBJECTIVES: This study aimed to evaluate the effectiveness of deep learning method for denoising and...

Incorporating computer vision on smart phone photographs into screening for inflammatory arthritis: results from an Indian patient cohort.

OBJECTIVES: Convolutional neural networks (CNNs) are increasingly used to classify medical images, b...

An artificial intelligence-based gout management system reduced chronic kidney disease incident and improved target serum urate achievement.

OBJECTIVES: Stage ≥3 chronic kidney disease (CKD) affects ∼25% of people with gout. The effects of u...

Repurposing FDA-approved drugs as NLRP3 inhibitors against inflammatory diseases: machine learning and molecular simulation approaches.

Activation of NLRP3 (NOD-like receptor family, pyrin domain-containing protein 3) has been associate...