Bacterial Infection

Natural deep eutectic solvents-based green extraction of vanillin: optimization, purification, and bioactivity assessment.

The sustainable extraction of natural compounds has recently attracted significant attention. The extraction of high-quality natural vanillin in active form is crucial for its efficient use in various industries, but conventional solvents are not suitable for this purpose. The flammability, volatility, and toxicity of organic solvents can harm extraction personnel, and their waste liquid can cause...

Antifungal activity of eumelanin-inspired indoylenepheyleneethynylene against .

is an opportunistic fungal pathogen that causes meningitis in >152,000 immunocompromised individuals annually, leading to 112,000 yearly deaths. The four classes of existing antifungal agents target plasma membrane sterols (ergosterol), nucleic acid synthesis, and cell wall synthesis. Existing drugs are not highly effective against , and antifungal drug resistance is an increasing problem. A nove...

Production of natural flavor compounds using fermented soybean meal extract and their biological potential: a comprehensive study.

This study aims to investigate the production of natural flavor compounds through the utilization of -fermented soybean meal extract and evaluate thei...

Effective microorganisms input efficiently improves the vegetation and microbial community of degraded alpine grassland.

Soil beneficial microorganism deficiency in the degraded grasslands have emerged as the major factors negatively impacting soil quality and vegetation...

Inactivation kinetics of selected pathogenic and non-pathogenic bacteria by aqueous ozone to validate minimum usage in purified water.

Ozone is often used as an antimicrobial agent at the final step in purified water processing. When used in purified bottled water manufacturing, resid...

BPAGS: a web application for bacteriocin prediction via feature evaluation using alternating decision tree, genetic algorithm, and linear support vector classifier.

The use of bacteriocins has emerged as a propitious strategy in the development of new drugs to combat antibiotic resistance, given their ability to k...

Antibiofilm peptides enhance the corrosion resistance of titanium in the presence of .

Titanium alloys have gained popularity in implant dentistry for the restoration of missing teeth and related hard tissues because of their biocompatib...

Ethnomedicinal uses, phytochemistry, and pharmacology of the genus : a review.

Although medicinal plants have been used by ethnic communities since ancient times to prevent and treat various diseases, only a few have been scienti...

antibacterial activity of antiretroviral drugs on key commensal bacteria from the human microbiota.

INTRODUCTION: Antiretroviral therapy has improved life expectancy in HIV-infected patients. However, people living with HIV under antiretroviral thera...

The critical role of neutrophil-endothelial cell interactions in sepsis: new synergistic approaches employing organ-on-chip, omics, immune cell phenotyping and modeling to identify new therapeutics.

Sepsis is a global health concern accounting for more than 1 in 5 deaths worldwide. Sepsis is now defined as life-threatening organ dysfunction caused...

Anti-ultraviolet, antibacterial, and biofilm eradication activities against of melanins and melanin derivatives from and .

and produced significant amounts of water-insoluble melanins, and our previous study successfully enhanced their water solubility by arginine modifi...

The antibacterial activity of berberine against : its therapeutic potential in inflammatory acne.

() is a major pathogen implicated in the evolution of acne inflammation. Inhibition of -induced inflammation is a prospective acne therapy strategy. ...

BactInt: A domain driven transfer learning approach for extracting inter-bacterial associations from biomedical text.

BACKGROUND: The healthy as well as dysbiotic state of an ecosystem like human body is known to be influenced not only by the presence of the bacterial...

ML-FGAT: Identification of multi-label protein subcellular localization by interpretable graph attention networks and feature-generative adversarial networks.

The prediction of multi-label protein subcellular localization (SCL) is a pivotal area in bioinformatics research. Recent advancements in protein stru...

GATR-3, a Peptide That Eradicates Preformed Biofilms of Multidrug-Resistant .

is a gram-negative bacterium that causes hospital-acquired and opportunistic infections, resulting in pneumonia, sepsis, and severe wound infections ...

Characterization of extended-spectrum beta-lactamase and carbapenemase genes in bacteria from environment in Burkina Faso.

INTRODUCTION: This study aimed to characterize extended-spectrum beta-lactamase (ESBL) and carbapenemase genes in bacteria from the environment in Bob...

Pregnancy-associated asymptomatic bacteriuria and antibiotic resistance in the Maternity and Children's Hospital, Arar, Saudi Arabia.

INTRODUCTION: The Ministry of Health in Saudi Arabia provides comprehensive antenatal care for all pregnant women with all required investigations. Ho...

Effects of Mannosylerythritol-Lipids-B on ATCC 6919.

Mannosylerythritol-lipids-B (MEL-B) are microbial-produced glycolipids with skincare properties, notably moisturizing, antimelanogenic, antimicrobial,...

Procalcitonin Levels in Identifying Bacterial Infections in Children with and without COVID-19.

OBJECTIVE: Elevated procalcitonin levels have been associated with bacterial infection in children. Observational studies reported high procalcitonin ...

Development of optimized functional clove fortified probiotic yoghurt.

We focused on assessing the antimicrobial effects of functional yoghurts supplemented with clove and probiotics. The formulation of aqueous clove extr...