Bacterial Infection

Raman spectroscopy-based adversarial network combined with SVM for detection of foodborne pathogenic bacteria.

Raman spectroscopy combined with artificial intelligence algorithms have been widely explored and focused on in recent years for food safety testing. It is still a challenge to overcome the cumbersome culture process of bacteria and the need for a large number of samples, which hinder qualitative analysis, to obtain a high classification accuracy. In this paper, we propose a method based on Raman ...

Silver Nanoparticles as an Effective Antimicrobial against Otitis Media Pathogens.

Otitis Media (OM) is the most common reason for U.S. children to receive prescribed oral antibiotics, leading to potential to cause antibiotic resistance. To minimize oral antibiotic usage, we developed polyvinylpyrrolidone-coated silver nanoparticles (AgNPs-PVP), which completely eradicated common OM pathogens, i.e., and non-typeable (NTHi) at 1.04μg/mL and 2.13μg/mL. The greater antimicrobial ...

Exopolysaccharides from a Scandinavian fermented milk viili increase butyric acid and members in the mouse gut.

Starter culture of viili contains lactic acid bacteria belonging to . These bacteria secrete large polysaccharides (EPSs) into milk, resulting in a ro...

Augmented sequence features and subcellular localization for functional characterization of unknown protein sequences.

Advances in high-throughput techniques lead to evolving a large number of unknown protein sequences (UPS). Functional characterization of UPS is signi...

Biocidal activity of Ba-doped CeO NPs against and bacterial strains.

Mishandling of antibiotics often leads to the development of multiple drug resistance (MDR) among microbes, resulting in the failure of infection trea...

Application of green synthesised copper iodide particles on cotton fabric-protective face mask material against COVID-19 pandemic.

Microorganisms cause variety of diseases that constitutes a severe threat to mankind. Due to the upsurge of many infectious diseases, there is a high ...

Chlorinated metabolites with antibacterial activities from a deep-sea-derived fungus.

Chromatographic separation of the solid cultures of a deep-sea-derived fungus (MCCC 3A00308) resulted in the isolation of eight compounds. Their stru...

Delivery mode and perinatal antibiotics influence the predicted metabolic pathways of the gut microbiome.

Delivery mode and perinatal antibiotics influence gut microbiome composition in children. Most microbiome studies have used the sequencing of the bact...

Synthesis of covalent bonding MWCNT-oligoethylene linezolid conjugates and their antibacterial activity against bacterial strains.

Nowadays, infectious diseases caused by drug-resistant bacteria have become especially important. Linezolid is an antibacterial drug active against cl...

Physically crosslinked PVA/graphene-based materials/aloe vera hydrogel with antibacterial activity.

Burn is a major skin injury that occurs worldwide. For second-degree burns, special treatment should be given for creating a suitable wound healing en...

Benzo[]thiazole-2-thiol bearing 2-oxo-2-substituted-phenylethan-1-yl as potent selective quorum sensing inhibitors of Gram-negative bacteria.

Quorum sensing is a well-known term for describing bacterial cell-cell communication. Bacteria use quorum sensing pathways to respond to external fact...

Machine Learning of Bacterial Transcriptomes Reveals Responses Underlying Differential Antibiotic Susceptibility.

antibiotic susceptibility testing often fails to accurately predict drug efficacies, in part due to differences in the molecular composition between...

Emergent antibacterial activity of -(thiazol-2-yl)benzenesulfonamides in conjunction with cell-penetrating octaarginine.

Hybrid antimicrobials that combine the effect of two or more agents represent a promising antibacterial therapeutic strategy. In this work, we have sy...

Antibacterial and antibiofilm activities of silver-decorated zinc ferrite nanoparticles synthesized by a gamma irradiation-coupled sol-gel method against some pathogenic bacteria from medical operating room surfaces.

This work aimed at the gamma irradiation-assisted synthesis of silver (Ag)-decorated ZnFeO (ZFO) ferrite nanoparticles (NPs), which were tested for th...

Fast identification of off-target liabilities in early antibiotic discovery with Fourier-transform infrared spectroscopy.

Structural modifications of known antibiotic scaffolds have kept the upper hand on resistance, but we are on the verge of not having antibiotics for m...

A machine learning approach identifies 5-ASA and ulcerative colitis as being linked with higher COVID-19 mortality in patients with IBD.

Inflammatory bowel diseases (IBD), namely Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammation within the gastrointestinal tract....

Interleukin-37 gene polymorphism and susceptibility to pulmonary tuberculosis among Iraqi patients.

BACKGROUND: Control of tuberculosis (TB) depends on a balance between host's immune factors and bacterial evasion strategies. Interleukin-37 (IL-37) i...

Swarming Aqua Sperm Micromotors for Active Bacterial Biofilms Removal in Confined Spaces.

Microscale self-propelled robots show great promise in the biomedical field and are the focus of many researchers. These tiny devices, which move and ...

Design, synthesis and mechanistic study of new benzenesulfonamide derivatives as anticancer and antimicrobial agents carbonic anhydrase IX inhibition.

Changes in gene expression cause uncontrolled cell proliferation and consequently tumor hypoxia. The tumor cells shift their metabolism to anaerobic g...

Promising antimicrobial and antibiofilm activities of reduced graphene oxide-metal oxide (RGO-NiO, RGO-AgO, and RGO-ZnO) nanocomposites.

Microbial infections are considered one of the most dangerous infections in humans due to their resistance to most antimicrobial agents. In this study...