Bacterial Infection

Salivary sCD14 as a potential biomarker of dental caries activity in adults.

CD14 is a co-receptor involved in the recognition of Gram-negative and Gram-positive bacteria, the latter known to cause dental caries. The aim of this study was to determine whether soluble CD14 (sCD14) in saliva was associated with caries activity and the collection method from the saliva. The study included 55 participants aged 20 to 40 years, 30 with dental caries and 25 caries-free controls. ...

Machine learning: novel bioinformatics approaches for combating antimicrobial resistance.

PURPOSE OF REVIEW: Antimicrobial resistance (AMR) is a threat to global health and new approaches to combating AMR are needed. Use of machine learning in addressing AMR is in its infancy but has made promising steps. We reviewed the current literature on the use of machine learning for studying bacterial AMR.

Pharmacokinetics of a Single Intramuscular Injection of Long-Acting Ceftiofur Crystalline-Free Acid in Cattle Egrets ( Bubulcus ibis).

We determined the pharmacokinetic properties of ceftiofur crystalline-free acid (CCFA), a long-acting antibiotic, after a single intramuscular injecti...

[Effects of Soil Microbial Diversity on the Phosphate Fraction in the Rhizosphere of in the Yeyahu Wetland in Beijing, China].

In this research, microorganisms in rhizosphere/non-rhizosphere soils of in the Yeyahu Wetland were studied. A sequential extraction procedure was us...

A predictive model to evaluate the impact of the cooling profile on growth of psychrotrophic bacteria in raw milk from conventional and robotic milking.

This Research Communication explores the usefulness of predictive modelling to explain bacterial behaviour during cooling. A simple dynamic lag phase ...

An integrative machine learning strategy for improved prediction of essential genes in Escherichia coli metabolism using flux-coupled features.

Prediction of essential genes helps to identify a minimal set of genes that are absolutely required for the appropriate functioning and survival of a ...

A Fresh Shine onCystic Fibrosis Inhalation Therapy: Antimicrobial Synergy of Polymyxin B in Combination with Silver Nanoparticles.

This in vitro study aimed to investigate the synergistic antibacterial activity of polymyxin B in combination with 2 nm silver nanoparticles (NPs) aga...

Influence of Incubation Conditions on the Nanoparticles Toxicity Based on Seed Germination and Bacterial Bioluminescence.

The effects of the modified incubation conditions of a conventional bioassay on the toxicity of partially soluble nanoparticles (NPs) were evaluated b...

Gene essentiality prediction based on fractal features and machine learning.

Essential genes are required for the viability of an organism. Accurate and rapid identification of new essential genes is of substantial theoretical ...

Improving Recognition of Antimicrobial Peptides and Target Selectivity through Machine Learning and Genetic Programming.

Growing bacterial resistance to antibiotics is spurring research on utilizing naturally-occurring antimicrobial peptides (AMPs) as templates for novel...

Recognizing and Predicting Thioether Bridges Formed by Lanthionine and β-Methyllanthionine in Lantibiotics Using a Random Forest Approach with Feature Selection.

BACKGROUND: Lantibiotics, which are usually produced from Gram-positive bacteria, are regarded as one type of special bacteriocins. Lantibiotics have ...

Chemical Composition and Antibacterial Activity of the Essential Oil of Vitex agnus-castus L. (Lamiaceae).

Abnormal multiplication of oral bacteria causes dental caries and dental plaque. These diseases continue to be major public health concerns worldwide,...

Effects of Caesalpinia sappan on pathogenic bacteria causing dental caries and gingivitis.

The present study explores antimicrobial activities of Caesalpinia sappan extracts against three strains of oral pathogenic bacteria; Streptococcus mu...

Antibacterial Activity of : Identification of Hispidulin and Dehydromelitensin-8-(4ꞌ-Hydroxy-Methacrylate).

Hexane, ethyl acetate and methanol extracts of leaves were investigated for their antibacterial activities against , , , , and . Hexane and ethyl ac...

Effect of Catechins, Green tea Extract and Methylxanthines in Combination with Gentamicin Against Staphylococcus aureus and Pseudomonas aeruginosa: - Combination therapy against resistant bacteria.

OBJECTIVES: Bacterial resistant infections have become a global health challenge and threaten the society's health. Thus, an urgent need exists to fin...

Antiphospholipid Syndrome with Antiβ2glicoprotein-1 Antibodies as the Cause of Recurrent Tibial Vein Thrombosis in SAPHO syndrome.

The antiphospholipid antibody syndrome is defined by the presence of antiphospholipid antibodies in patients with recurrent venous or arterial thrombo...

[Spontaneous bacterial peritonitis].

AIM OF STUDY: Spontaneous bacterial peritonitis (SBP) is the most frequent infectious complication of liver cirrhosis with serious consequences. Initi...

Report: Antibacterial activity of a peptide derived from HIV-1 MN strain gp41 envelope glycoprotein against methicillin-resistant Staphylococcus aureus.

Peptides derived from HIV-1 transmembrane proteins have been extensively studied for antimicrobial activities, and they are known as antimicrobial pep...

Machine learning-, rule- and pharmacophore-based classification on the inhibition of P-glycoprotein and NorA.

The efflux pumps P-glycoprotein (P-gp) in humans and NorA in Staphylococcus aureus are of great interest for medicinal chemists because of their impor...

Ventilator-Associated Pneumonia: Comparing Cadaveric Liver Transplant and Non-Transplant Surgical Patients.

Ventilator-associated pneumonia is a frequent complication in intensive care surgical patients, particularly those with high severity scores on admiss...