Cardiovascular

Integration of 101 machine learning algorithm combinations to unveil m6A/m1A/m5C/m7G-associated prognostic signature in colorectal cancer.

Colorectal cancer (CRC) is the most common malignancy in the digestive system, with a lower 5-year overall survival rate. There is increasing evidence showing that RNA modification regulators such as m1A, m5C, m6A, and m7G play crucial roles in tumor progression. However, the prognostic role of integrated m6A/m5C/m1A/m7G methylation modifications in CRC has not been reported and requires further i...

Radiation oncology at crossroads: Rise of AI and managing the unexpected.

Integrating artificial intelligence (AI) into radiation oncology has revolutionized clinical workflows, enhancing efficiency, safety, and quality. However, this transformation comes with a price of increased complexity and the emergence of unpredictable events. This letter proposes a framework based on high reliability organization (HRO) principles for managing real-time, unforeseen events. The fr...

CT-Based Deep Learning Predicts Prognosis in Esophageal Squamous Cell Cancer Patients Receiving Immunotherapy Combined with Chemotherapy.

RATIONALE AND OBJECTIVES: Immunotherapy combined with chemotherapy has improved outcomes for some esophageal squamous cell carcinoma (ESCC) patients, ...

An interpretable ensemble model combining handcrafted radiomics and deep learning for predicting the overall survival of hepatocellular carcinoma patients after stereotactic body radiation therapy.

PURPOSE: Hepatocellular carcinoma (HCC) remains a global health concern, marked by increasing incidence rates and poor outcomes. This study seeks to d...

MLAR-UNet: LDCT image denoising based on U-Net with multiple lightweight attention-based modules and residual reinforcement.

Computed tomography (CT) is a crucial medical imaging technique which uses x-ray radiation to identify cancer tissues. Since radiation poses a signifi...

Use of machine learning algorithms to construct models of symptom burden cluster risk in breast cancer patients undergoing chemotherapy.

PURPOSE: To develop models using different machine learning algorithms to predict high-risk symptom burden clusters in breast cancer patients undergoi...

Monitoring Immunohistochemical Staining Variations Using Artificial Intelligence on Standardized Controls.

Quality control of immunohistochemistry (IHC) slides is crucial to ascertain accurate patient management. Visual assessment is the most commonly used ...

Comparative analysis of machine learning models for predicting pathological complete response to neoadjuvant chemotherapy in breast cancer: An MRI radiomics approach.

PURPOSE: The aim of this work is to compare different machine learning models for predicting pathological complete response (pCR) to neoadjuvant chemo...

DeepInterAware: Deep Interaction Interface-Aware Network for Improving Antigen-Antibody Interaction Prediction from Sequence Data.

Identifying interactions between candidate antibodies and target antigens is a key step in developing effective human therapeutics. The antigen-antibo...

Does Deep Learning Reconstruction Improve Ureteral Stone Detection and Subjective Image Quality in the CT Images of Patients with Metal Hardware?

Diagnosing ureteral stones with low-dose CT in patients with metal hardware can be challenging because of image noise. The purpose of this study was ...

A promising AI based super resolution image reconstruction technique for early diagnosis of skin cancer.

Skin cancer can be prevalent in people of any age group who are exposed to ultraviolet (UV) radiation. Among all other types, melanoma is a notable se...

Machine learning prediction of breast cancer local recurrence localization, and distant metastasis after local recurrences.

Local recurrences (LR) can occur within residual breast tissue, chest wall, skin, or newly formed scar tissue. Artificial intelligence (AI) technologi...

CT-Less Whole-Body Bone Segmentation of PET Images Using a Multimodal Deep Learning Network.

In bone cancer imaging, positron emission tomography (PET) is ideal for the diagnosis and staging of bone cancers due to its high sensitivity to malig...

Next-generation sequencing based deep learning model for prediction of HER2 status and response to HER2-targeted neoadjuvant chemotherapy.

INTRODUCTION: For patients with breast cancer, the amplification of Human Epidermal Growth Factor 2 (HER2) is closely related to their prognosis and t...

An assessment of breast cancer HER2, ER, and PR expressions based on mammography using deep learning with convolutional neural networks.

Mammography is the recommended imaging modality for breast cancer screening. Expressions of human epidermal growth factor receptor 2 (HER2), estrogen ...

A comparison of different machine learning classifiers in predicting xerostomia and sticky saliva due to head and neck radiotherapy using a multi-objective, multimodal radiomics model.

. Although radiotherapy techniques are a primary treatment for head and neck cancer (HNC), they are still associated with substantial toxicity and sid...

You get the best of both worlds? Integrating deep learning and traditional machine learning for breast cancer risk prediction.

Breast Cancer is the most commonly diagnosed cancer worldwide. While screening mammography diminishes the burden of this disease, it has some flaws re...

Leveraging paired mammogram views with deep learning for comprehensive breast cancer detection.

Employing two standard mammography views is crucial for radiologists, providing comprehensive insights for reliable clinical evaluations. This study i...

Habitat-Based Radiomics for Revealing Tumor Heterogeneity and Predicting Residual Cancer Burden Classification in Breast Cancer.

PURPOSE: To investigate the feasibility of characterizing tumor heterogeneity in breast cancer ultrasound images using habitat analysis technology and...

Integrating Eye Tracking With Grouped Fusion Networks for Semantic Segmentation on Mammogram Images.

Medical image segmentation has seen great progress in recent years, largely due to the development of deep neural networks. However, unlike in compute...