Latest AI and machine learning research in chemotherapy for healthcare professionals.
Patients with locally advanced laryngeal and hypopharyngeal squamous cell carcinoma (LA-LHSCC) urgently need precise treatment strategies to improve the prognosis due to severe laryngeal functional impairment following traditional surgery and chemoradiotherapy. This study focuses on the mechanism of sensitivity to induction chemotherapy (IC), integrating the GSE184072 and TCGA-HNSC data sets to sc...
BACKGROUND: While triplet therapy (HTI), which combines hepatic arterial infusion chemotherapy (HAIC) with tyrosine kinase inhibitors and immune checkpoint inhibitors, is widely used in the treatment of large hepatocellular carcinoma (HCC), there are few reports about its efficacy versus HAIC, and no reliable methods are available for promptly predicting HTI response.
Therapeutic clinical trial enrollment does not match glioma incidence across demographics. Traditional statistical methods have identified independent...
Urethral recurrence (UR) following radical cystectomy for bladder cancer represents an aggressive disease failure with typically poor survival outcome...
BACKGROUND: Cancer poses a significant health threat, causing millions of deaths annually. Although chemotherapy-based comprehensive therapies are com...
Elucidating the anti-tumor role of tumor-draining lymph nodes (tdLNs) in patients could offer critical mechanistic insight and shift therapeutic strat...
Multispecific antibodies have redefined the immunotherapeutic landscape in hematologic malignancies. Bispecific antibodies (BsAbs), which redirect cyt...
BACKGROUND: Accurate preoperative prediction of major pathological response or pathological complete response after neoadjuvant chemo-immunotherapy re...
BACKGROUND: Postoperative pancreatic fistula (POPF) remains one of the most relevant complications following pancreaticoduodenectomy (PD), significant...
Atomically dispersed metal-nitrogen-carbon (M-N-C) materials, characterized by well-defined coordination structures, have emerged as promising candida...
In silico trials, utilizing mathematical models calibrated with clinical data, present a transformative approach to expedite drug development. We prop...
BACKGROUND: The TCbHP regimen, consisting of combining docetaxel (T), carboplatin (Cb), trastuzumab (H), and pertuzumab (P), is the preferred neoadjuv...
: Serum diagnostic tests for alopecia areata may be used to monitor response to treatment, aiding in the objective assessment of disease activity and ...
In recent years,immunotherapy,particularly immune checkpoint inhibitors,has been widely used in the treatment of both solid and non-solid tumors,and i...
BACKGROUND: This study aims to evaluate the efficacy of chemotherapy and optimize treatment strategies for patients with advanced ovarian cancer.
In this study, a novel Caputo fractional-order model is proposed to represent the complex interactions among stem cells, effector cells, and tumor cel...
The composition and function of glycans are very complex thus manual data interpretation of their structural elucidation is difficult. Capillary elect...
: The predictive value of muscle-related indicators in triple-negative breast cancer (TNBC) patients undergoing neoadjuvant chemotherapy (NAC) remains...
BACKGROUND: National guidelines (GLs) for surgical cytoreduction (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in the management of peri...
BACKGROUND: Predicting colon cancer recurrence is crucial for determining the need for adjuvant therapy after curative resection. However, clinical de...