Clinical Trials

Role of Reference Frames for a Safe Human-Robot Interaction.

Safety plays a key role in human-robot interactions in collaborative robot (cobot) applications. This paper provides a general procedure to guarantee safe workstations allowing human operations, robot contributions, the dynamical environment, and time-variant objects in a set of collaborative robotic tasks. The proposed methodology focuses on the contribution and the mapping of reference frames. M...

Evaluation of a Medical Interview-Assistance System Using Artificial Intelligence for Resident Physicians Interviewing Simulated Patients: A Crossover, Randomized, Controlled Trial.

Medical interviews are expected to undergo a major transformation through the use of artificial intelligence. However, artificial intelligence-based systems that support medical interviews are not yet widespread in Japan, and their usefulness is unclear. A randomized, controlled trial to determine the usefulness of a commercial medical interview support system using a question flow chart-type appl...

Automatic Extraction of Comprehensive Drug Safety Information from Adverse Drug Event Narratives in the Korea Adverse Event Reporting System Using Natural Language Processing Techniques.

INTRODUCTION: Concerns have been raised over the quality of drug safety information, particularly data completeness, collected through spontaneous rep...

Randomized Controlled Feasibility Trial of Robot-assisted Versus Conventional Open Partial Nephrectomy: The ROBOCOP II Study.

BACKGROUND: There is no evidence from randomized controlled trials (RCTs) comparing robot-assisted partial nephrectomy (RAPN) and open partial nephrec...

Emerging technology in agriculture: Opportunities and considerations for occupational safety and health researchers.

INTRODUCTION: A variety of factors are driving the development of robotics and automation in the agriculture industry including the nature of work, wo...

Modeling contact forces during human-robot interactions for performing activities of daily living.

This study aims to characterize contact forces between humans and tools during activities of daily living (ADL) to provide information to a personal c...

Protocol of a prospective multicenter randomized controlled trial of robot-assisted stereotactic lesioning in the treatment of focal drug-resistant epilepsy.

BACKGROUND: This protocol describes the design of a multicenter randomized controlled trial of robot-assisted stereotactic lesioning versus epileptoge...

Controversies and strengths of robot-assisted mastectomy.

Nipple-sparing mastectomy (NSM) is used to improve cosmetic outcomes while maintaining oncological safety in patients with early breast cancer; howeve...

CONFIDENT-trial protocol: a pragmatic template for clinical implementation of artificial intelligence assistance in pathology.

INTRODUCTION: Artificial intelligence (AI) has been on the rise in the field of pathology. Despite promising results in retrospective studies, and sev...

Inference for treatment-specific survival curves using machine learning.

In the absence of data from a randomized trial, researchers may aim to use observational data to draw causal inference about the effect of a treatment...

Deep learning phase error correction for cerebrovascular 4D flow MRI.

Background phase errors in 4D Flow MRI may negatively impact blood flow quantification. In this study, we assessed their impact on cerebrovascular flo...

FRSR: Framework for real-time scene reconstruction in robot-assisted minimally invasive surgery.

3D reconstruction of the intra-operative scenes provides precise position information which is the foundation of various safety related applications i...

Machine Learning in Clinical Trials: A Primer with Applications to Neurology.

We reviewed foundational concepts in artificial intelligence (AI) and machine learning (ML) and discussed ways in which these methodologies may be emp...

Research Participant Selection Bias in the Workshop Using Socially Assistive Robots for Older Adults and Its Effect on Population Representativeness.

Every research participant has their own personality characteristics. For example, older adults assisted by socially assistive robots (SAR) may have t...

Trends in Robotics Research in Occupational Safety and Health: A Scientometric Analysis and Review.

Robots have been deployed in workplaces to assist, work alongside, or collaborate with human workers on various tasks, which introduces new occupation...

Robotic Versus Laparoscopic Ventral Hernia Repair: Two-Year Results From a Prospective, Multicenter, Blinded Randomized Clinical Trial.

OBJECTIVE: Report the 2-year outcomes of a multicenter randomized controlled trial comparing robotic versus laparoscopic intraperitoneal onlay mesh ve...

The effects of Robot-assisted gait training and virtual reality on balance and gait in stroke survivors: A randomized controlled trial.

BACKGROUND: Stroke survivors often experience balance and gait problems, which can affect their quality of life and independence in daily living activ...

Tafoxiparin, a novel drug candidate for cervical ripening and labor augmentation: results from 2 randomized, placebo-controlled studies.

BACKGROUND: Slow progression of labor is a common obstetrical problem with multiple associated complications. Tafoxiparin is a depolymerized form of h...

Virtual Screening of Nrf2 Dietary-Derived Agonists and Safety by a New Deep-Learning Model and Verified and .

Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is an essential regulatory target of antioxidants, but the lack of Nrf2 active site information has...

Weight-shifting-based robot control system improves the weight-bearing rate and balance ability of the static standing position in hip osteoarthritis patients: a randomized controlled trial focusing on outcomes after total hip arthroplasty.

BACKGROUND: After a total hip arthroplasty (THA), standing and walking balance are greatly affected in the early stages of recovery, so it is importan...