Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Broad-Spectrum Profiling of Drug Safety via Learning Complex Network.

Drug safety is a severe clinical pharmacology and toxicology problem that has caused immense medical and social burdens every year. Regretfully, a reproducible method to assess drug safety systematically and quantitatively is still missing. In this study, we developed an advanced machine learning model for de novo drug safety assessment by solving the multilayer drug-gene-adverse drug reaction (AD...

Feb 28 2020 31868917

A randomized controlled study incorporating an electromechanical gait machine, the Hybrid Assistive Limb, in gait training of patients with severe limitations in walking in the subacute phase after stroke.

Early onset, intensive and repetitive, gait training may improve outcome after stroke but for patients with severe limitations in walking, rehabilitation is a challenge. The Hybrid Assistive Limb (HAL) is a gait machine that captures voluntary actions and support gait motions. Previous studies of HAL indicate beneficial effects on walking, but these results need to be confirmed in blinded, randomi...

Feb 28 2020 32109255
Alendronate/Vitamin D for attenuating bone mineral density loss during antiretroviral initiation: a pilot randomized controlled trial.

Antiretroviral therapy (ART) initiation is associated with decreases in bone mineral density (BMD). To plan for a larger trial, we sought to obtain p...

Feb 27 2020 32106792
Artificial intelligence in health care: accountability and safety.

The prospect of patient harm caused by the decisions made by an artificial intelligence-based clinical tool is something to which current practices of...

Feb 25 2020 32284648
The Metabolic Rainbow: Deep Learning Phase I Metabolism in Five Colors.

Metabolism of drugs affects their absorption, distribution, efficacy, excretion, and toxicity profiles. Metabolism is routinely assessed experimentall...

Feb 24 2020 32040319
A comparison between Artificial Neural Network and Hybrid Intelligent Genetic Algorithm in predicting the severity of fixed object crashes among elderly drivers.

Run-off-road (ROR) crashes have always been a major concern as this type of crash is usually associated with a considerable number of serious injury a...

Feb 14 2020 32065912
Effects of interactive robot-enhanced hand rehabilitation in treatment of paediatric hand-burns: A randomized, controlled trial with 3-months follow-up.

PURPOSE: To evaluate the effectiveness of the robotic-assisted exercise with virtual gaming on total active range of motion (ROM) of the digits, hand ...

Feb 11 2020 32057546
Does robot-assisted gait training improve mobility, activities of daily living and quality of life in stroke? A single-blinded, randomized controlled trial.

The purpose of this study was to investigate the effects of robot-assisted gait training (RAGT) on mobility, activities of daily living (ADLs), and qu...

Jan 28 2020 31989505
Robot-assisted radical cystectomy: Review of surgical technique, and perioperative, oncological and functional outcomes.

Since the introduction of robot-assisted radical cystectomy, efforts have been made to meet the standards in terms of perioperative safety and oncolog...

Jan 25 2020 31981379
Big Data Analytics and Sensor-Enhanced Activity Management to Improve Effectiveness and Efficiency of Outpatient Medical Rehabilitation.

Numerous societal trends are compelling a transition from inpatient to outpatient venues of care for medical rehabilitation. While there are advantage...

Jan 24 2020 31991582
Integrating machine-generated mortality estimates and behavioral nudges to promote serious illness conversations for cancer patients: Design and methods for a stepped-wedge cluster randomized controlled trial.

INTRODUCTION: Patients with cancer often receive care that is not aligned with their personal values and goals. Serious illness conversations (SICs) b...

Jan 23 2020 31982648
Beyond the Randomized Clinical Trial: Innovative Data Science to Close the Pediatric Evidence Gap.

Despite the application of advanced statistical and pharmacometric approaches to pediatric trial data, a large pediatric evidence gap still remains. H...

Jan 22 2020 31863465
Image Quality and Lesion Detection on Deep Learning Reconstruction and Iterative Reconstruction of Submillisievert Chest and Abdominal CT.

The objective of this study was to compare image quality and clinically significant lesion detection on deep learning reconstruction (DLR) and iterat...

Jan 22 2020 31967501
Modeling and optimization by particle swarm embedded neural network for adsorption of methylene blue by jicama peroxidase immobilized on buckypaper/polyvinyl alcohol membrane.

Jicama peroxidase (JP) immobilized functionalized Buckypaper/Polyvinyl alcohol (BP/PVA) membrane was synthesized and evaluated as a promising nanobioc...

Jan 21 2020 32044575
Fuzzy Logic-Based Risk Assessment of a Parallel Robot for Elbow and Wrist Rehabilitation.

A few decades ago, robotics started to be implemented in the medical field, especially in the rehabilitation of patients with different neurological d...

Jan 19 2020 31963917
Adaptive Ankle Resistance from a Wearable Robotic Device to Improve Muscle Recruitment in Cerebral Palsy.

Individuals with cerebral palsy can have weak and poorly coordinated ankle plantar flexor muscles that contribute to inefficient walking patterns. Pre...

Jan 16 2020 31950309
Predicting real-time traffic conflicts using deep learning.

Recently, technologies for predicting traffic conflicts in real-time have been gaining momentum due to their proactive nature of application and the g...

Jan 10 2020 31931409
Motivational interviewing and culture for urban Native American youth (MICUNAY): A randomized controlled trial.

To date, few programs that integrate traditional practices with evidence-based practices have been developed, implemented, and evaluated with urban Am...

Dec 28 2019 32087841
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