Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Trial Approach for Biomedical Products: A Regulatory Perspective.

The modern pharmaceutical industry is transitioning from traditional methods to advanced technologies like artificial intelligence. In the current scenario, continuous efforts are being made to incorporate computational modeling and simulation in drug discovery, development, design, and optimization. With the advancement in technology and modernization, many pharmaceutical companies are approachin...

Jan 1 2022 34986768
Virtual reality combined with robot-assisted gait training to improve walking ability of children with cerebral palsy: A randomized controlled trial.

BACKGROUND: Children with cerebral palsy (CP) have disorders of posture and movement and which can limit physical activities such as walkingOBJECTIVE:...

Jan 1 2022 35661029
A systematic review on natural language processing systems for eligibility prescreening in clinical research.

OBJECTIVE: We conducted a systematic review to assess the effect of natural language processing (NLP) systems in improving the accuracy and efficiency...

Dec 28 2021 34725689
Effects of robot (SUBAR)-assisted gait training in patients with chronic stroke: Randomized controlled trial.

BACKGROUND: SUBAR is a new ground walking exoskeletal robot. The objective of this study is to investigate SUBAR-assisted gait training's effects in p...

Dec 3 2021 35049203
Realizing the Power of Text Mining and Natural Language Processing for Analyzing Patient Safety Event Narratives: The Challenges and Path Forward.

Patient safety event (PSE) reports are a useful lens to understand hazards and patient safety risks in healthcare systems. However, patient safety off...

Dec 1 2021 34852413
Effectiveness and safety of elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate single-tablet combination among HIV-infected patients in Turkey: results from a real world setting.

BACKGROUND: Efficacy of elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil (E/C/F/TDF) in treatment-naĆÆve and experienced patients with HIV in...

Dec 1 2021 35283956
Efficacy and safety of carboplatin with nab-paclitaxel versus docetaxel in older patients with squamous non-small-cell lung cancer (CAPITAL): a randomised, multicentre, open-label, phase 3 trial.

BACKGROUND: In Japan, docetaxel, a cytotoxic monotherapy, is the standard drug administered to older patients with advanced non-small-cell lung cancer...

Dec 1 2021 36098037
The quantification and clinical analysis of depression and anxiety in patients undergoing Da Vinci robot-assisted radical gastrectomy and open radical gastrectomy.

The purpose of paper is to investigate the depression and anxiety as well as independent influential factors between patients who underwent Da Vinci r...

Nov 1 2021 34596103
Federated Learning via Conditional Mutual Learning for Alzheimer's Disease Classification on T1w MRI.

Data-driven deep learning has been considered a promising method for building powerful models for medical data, which often requires a large amount of...

Nov 1 2021 34891771
[A prospective randomized controlled trial on the short-term effectiveness of domestic robot-assisted total knee arthroplasty].

OBJECTIVE: To explore the short-term effectiveness of domestic robot-assisted total knee arthroplasty (RATKA) conducted by a prospective randomized co...

Oct 15 2021 34651477
RoBoT: a robust Bayesian hypothesis testing method for basket trials.

A basket trial in oncology encompasses multiple "baskets" that simultaneously assess one treatment in multiple cancer types or subtypes. It is well-re...

Oct 13 2021 32061093
Efficacy and safety of a switch from twice-daily tacrolimus to once-daily generic tacrolimus in stable liver transplant patients.

BACKGROUND: Once-daily tacrolimus reduces non-compliance relative to twice-daily tacrolimus. However, little is known about the safety and efficacy of...

Sep 30 2021 35769244
Preventing dataset shift from breaking machine-learning biomarkers.

Machine learning brings the hope of finding new biomarkers extracted from cohorts with rich biomedical measurements. A good biomarker is one that give...

Sep 28 2021 34585237
Clinical effect and standardization of indocyanine green angiography in the laparoscopic colorectal surgery.

Anastomotic complications occur after 5% to 20% of operations for rectosigmoid colon cancer. The intestinal perfusion status at the anastomotic site i...

Sep 15 2021 35600102
Assessment of Automating Safety Surveillance From Electronic Health Records: Analysis for the Quality and Safety Review System.

BACKGROUND AND OBJECTIVES: In an effort to improve and standardize the collection of adverse event data, the Agency for Healthcare Research and Qualit...

Sep 1 2021 28671914
Children's Pain During IV Induction: A Randomized-Controlled Trial With the MEDiĀ® Robot.

OBJECTIVE: This study examined the impact of a humanoid robot (MEDiĀ®) programmed to teach deep breathing as a coping strategy, on children's pain and ...

Aug 19 2021 33764470
Randomized Self-Organizing Map.

We propose a variation of the self-organizing map algorithm by considering the random placement of neurons on a two-dimensional manifold, following a ...

Jul 26 2021 34310672
More than meets the eye: Using AI to identify reduced heart function by electrocardiograms.

Electrocardiographic (ECG) assessment of patients with suspected heart disease is a bedrock of cardiology for diagnosing conduction system disease, ar...

Jul 9 2021 35590216
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