Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Automating the Identification of Patient Safety Incident Reports Using Multi-Label Classification.

Automated identification provides an efficient way to categorize patient safety incidents. Previous studies have focused on identifying single incident types relating to a specific patient safety problem, e.g., clinical handover. In reality, there are multiple types of incidents reflecting the breadth of patient safety problems and a single report may describe multiple problems, i.e., it can be as...

Jan 1 2017 29295168

Automated Classification of Multi-Labeled Patient Safety Reports: A Shift from Quantity to Quality Measure.

Over the past two decades, there have seen an ever-increasing amount of patient safety reports yet the capacity of extracting useful information from the reports remains limited. Classification of patient safety reports is the first step of performing a downstream analysis. In practice, the manual review processes for classification are labor-intense. Studies have shown that the reports are often ...

Jan 1 2017 29295266
Active Surveillance Use Among a Low-risk Prostate Cancer Population in a Large US Payer System: 17-Gene Genomic Prostate Score Versus Other Risk Stratification Methods.

Many men with low-risk prostate cancer (PCa) receive definitive treatment despite recommendations that have been informed by two large, randomized tri...

Jan 1 2017 29472824
Safety and Early Satisfaction Assessment of Patients Seeking Nonsurgical Rhinoplasty with Filler.

BACKGROUND: Nonsurgical aesthetic treatments are usually preferred by patients because their effects are visible immediately after the treatment and p...

Jan 1 2017 29491656
Effect of Tinidazole on Norfloxacin Disposition.

Co-administration of norfloxacin (NFX) and tinidazole (TNZ) has been used for the treatment of gastrointestinal and urinary tract infections. Concomit...

Jan 1 2017 29552066
Effect of Hypertonic Saline 5% on Early Graft Function and Urinary Interleukin 18 and Neutrophil Gelatinase-Associated Lipocalin in Deceased-Donor Kidney Transplantation.

Ischemia reperfusion injury (IRI) is one of the main causes of delayed graft function (DGF) in deceased-donor kidney transplantation (DDKT). Evidences...

Jan 1 2017 29552067
Study of The Effects of N-Acetylcysteine on Oxidative Stress Status of Patients on Maintenance-Hemodialysis Undergoing Cadaveric Kidney Transplantation.

N-acetylcysteine (NAC) is a potent antioxidant that acts through regenerating glutathione stores and scavenging oxygen-free radicals. This study asses...

Jan 1 2017 29552072
Does advanced chronic kidney disease impact transjugular intrahepatic portosystemic shunt efficacy and safety?

BACKGROUND AND STUDY AIMS: There are currently limited data available summarizing the clinical outcomes and safety of transjugular intrahepatic portos...

Jan 1 2017 29560689
Effects of premedication with Pronase for endoscopic ultrasound of the stomach: A randomized controlled trial.

AIM: To analyze the effects of premedication with Pronase for endoscopic ultrasound (EUS) examination of the stomach.

Dec 28 2016 28082820
A Double-Blind Randomized Clinical Trial Comparing the Effect of Neostigmine and Metoclopramide on Gastric Residual Volume of Mechanically Ventilated ICU Patients.

BACKGROUND: In critically ill patients, enteral feeding through the nasogastric tube is the method of choice for nutritional support. Gastrointestinal...

Dec 1 2016 28077899
A case series of the safety and efficacy of testosterone replacement therapy in renal failure and kidney transplant patients.

BACKGROUND: Hypogonadism is common in patients with renal dysfunction and does not always correct following transplantation. Recent studies show incre...

Dec 1 2016 28078211
Relevance of angiopoietin-2 and soluble P-selectin levels in patients with pulmonary arterial hypertension receiving combination therapy with oral treprostinil: a FREEDOM-C2 biomarker substudy.

UNLABELLED: Studies have suggested roles for angiopoietin-2 (Ang-2) and soluble P-selectin (sP-selectin) as biomarkers of disease severity and treatme...

Dec 1 2016 28090293
The Effects of First-Line Anti-Tuberculosis Drugs on the Actions of Vitamin D in Human Macrophages.

Tuberculosis (TB) is a major global health problem. Patients with TB have a high rate of vitamin D deficiency, both at diagnosis and during the course...

Dec 1 2016 28111615
Influence of Oral Progesterone Administration on Drug-Induced QT Interval Lengthening: A Randomized, Double-Blind, Placebo-Controlled Crossover Study.

OBJECTIVES: We tested the hypothesis that oral progesterone administration attenuates drug-induced QT interval lengthening.

Dec 1 2016 28451647
[Analysis of Diemailing Kudiezi injection use in real world in 7 189 patients with cerebral infarction].

This is a study based on hospital intensive monitoring to explore medication use of Diemailing Kudiezi injection(one Chinese herbal medicine injection...

Dec 1 2016 28933125
A Randomized Controlled Trial Study on the Effect of Adding Dexmedetomidine to Bupivacaine in Supraclavicular Block Using Ultrasound Guidance.

BACKGROUND: The benefits of regional anesthetic techniques are well established. Use of additives to local anesthetics can prolong these benefits. The...

Nov 1 2016 28450772
30 Years of Robotic Surgery.

The idea of reproducing himself with the use of a mechanical robot structure has been in man's imagination in the last 3000 years. However, the use of...

Oct 1 2016 27177648
Robot-assisted gait training improves brachial-ankle pulse wave velocity and peak aerobic capacity in subacute stroke patients with totally dependent ambulation: Randomized controlled trial.

OBJECTIVE: Brachial-ankle pulse wave velocity (baPWV) evaluates arterial stiffness and also predicts early outcome in stroke patients. The objectives ...

Oct 1 2016 27741123
[Safety and Tolerance of Healthy People to Injection of Astragalosides-a New Drug for Coronary Heart Disease].

OBJECTIVES: To assess the safety and tolerance of healthy volunteers to as tragalosides injection (AGI), and to determine a safe dose range for phase ...

Sep 1 2016 28598103
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