Oncology/Hematology

Colon Cancer

Latest AI and machine learning research in colon cancer for healthcare professionals.

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Machine learning-based risk modeling for safety-focused learning curve assessment in robotic left-sided colorectal cancer surgery.

The transition from laparoscopic to robotic surgery for left-sided colorectal cancer raises safety concerns during the learning curve, particularly when complex cases are preferentially selected for the robotic platform. We evaluated a machine learning-based framework for risk-adjusted safety monitoring of robotic implementation, using outcomes from an established laparoscopic program as the refer...

Jan 19 2026 41553590

Establishment of threshold of human gut microbes and risk assessment system for colorectal cancer.

BACKGROUND: Being involved in the occurrence of colorectal cancer (CRC), gut microbes are potential targets for early diagnosis of CRC. Defining the threshold of these characteristic bacteria could provide a basis for the clinical application of microorganisms as novel tumor markers for CRC. OBJECTIVE: To sort out and define the threshold of related bacteria and the ecological characteristics of g...

Jan 19 2026 41558386
Computer Aided Polyp Detection Multi-center International Randomized Controlled Study with a Focus on Community Clinics: GAIN Clinical Trial.

BACKGROUND/AIMS: Computer-aided polyp detection (CADe) systems can enhance polyp detection, although their performance has largely been evaluated at a...

Jan 16 2026 41548723
LGDUnet: A dual-branch network for weakly supervised gland segmentation in H&E stained histopathological images.

Glandular segmentation holds significant importance in the pathological analysis of hematoxylin and eosin (H&E) stained images, particularly in the di...

Jan 16 2026 41549958
Radiomics profiling combined with clinical risk factors for preoperative Lymphatic Metastasis prediction in Colorectal cancer: A multicenter study.

PURPOSE: Accurate preoperative assessment of regional lymphatic metastases (LNM) is essential for effective surgical selection of patients with colore...

Jan 16 2026 41544025
Rethinking U-Net architecture in medical imaging: Advancing the efficient and interpretable UKAN-CBAM framework for colorectal polyp segmentation.

Prompt detection of colorectal polyps is essential for preventing colorectal cancer, a leading cause of cancer-related deaths worldwide. However, manu...

Jan 15 2026 41558310
Exploring structural diversity and dynamic stability of small-molecule PRMT5 inhibitors through machine learning-based QSAR and molecular modelling.

Protein arginine methyltransferase 5 (PRMT5) is a key epigenetic enzyme that catalyses symmetric arginine methylation on histone and non-histone prote...

Jan 14 2026 41533017
Impact of fine-grained learning rate configuration on the performance of medical image segmentation models.

Research on deep learning for medical image segmentation has shifted from single-modality networks to multimodal data fusion. Updating the parameters ...

Jan 14 2026 41534111
Approaches to assessing completeness of polyp resections in clinical practice: a systematic scoping review.

BACKGROUND: Protocols for standardized assessment of complete colorectal polyp resection are lacking. This may contribute to divergent quality standar...

Jan 14 2026 41534867
Integrated Single Cell Spatial Analysis Reveals Dysregulated Basal Progenitor Cells in Ulcerative Colitis Pathogenesis: A Multi Omics Study.

BACKGROUND AND AIMS: Ulcerative colitis (UC), a chronic inflammatory bowel disease, causes persistent mucosal inflammation and epithelial dysfunction....

Jan 14 2026 41542331
The 2025 top 10 list of endoscopy topics in medical publishing: an annual review by the American Society for Gastrointestinal Endoscopy Editorial Board.

Using a systematic literature search of original articles published during 2025 in Gastrointestinal Endoscopy (GIE) and other high-impact medical and ...

Jan 13 2026 41539580
AI for screening in healthcare: promise and challenges.

Artificial intelligence (AI) is reshaping population screening, yet the translation from laboratory performance to population benefit remains limited....

Jan 12 2026 41524988
Deep learning in enhanced CT imaging: predicting invasion depth of rectal adenocarcinoma.

PURPOSE: This study aims to develop and evaluate a deep learning model, RectoDepthAI, that leverages enhanced CT images to accurately assess the tumor...

Jan 12 2026 41524989
CTSB-positive tumor-associated macrophages shape prognosis and therapeutic response in lung adenocarcinoma.

BACKGROUND: Lung adenocarcinoma (LUAD) remains a major clinical challenge in assessment of clinical outcomes and therapeutic response. Although tumor-...

Jan 12 2026 41520491
C2HFusion: Clinical context-driven hierarchical fusion of multimodal data for personalized and quantitative prognostic assessment in pancreatic cancer.

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Accurate prognostic modeling enables reliable risk stratification to identi...

Jan 11 2026 41564638
Uncovering the potential of pathomics: prognostic prediction and mechanistic investigation of pancreatic cancer.

A machine learning-based pathomics model was investigated for its value and biological significance in predicting overall survival (OS) after surgery ...

Jan 8 2026 41508286
Emerging Diagnostic Indications for Endoscopic Ultrasound.

Endoscopic ultrasound (EUS) has evolved from a diagnostic imaging tool into a versatile platform that enables high-precision access, sampling, and the...

Jan 7 2026 41498716
Artificial Intelligence and Its Role in Endoscopic Adenoma and Cancer Detection.

Colorectal cancer incidence and mortality have declined over time, due in part to high-quality screening and surveillance colonoscopy. Nevertheless, p...

Jan 7 2026 41948156
Application of artificial intelligence in colonoscopy imaging for polyp analysis-A systematic review.

The colon is a major component of the digestive system, so early detection of colorectal polyps is essential in preventing colorectal cancer, which is...

Jan 7 2026 41621228
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