Colon Cancer

Development of Multiparametric Prognostic Models for Stereotactic Magnetic Resonance Guided Radiation Therapy of Pancreatic Cancers.

PURPOSE: Stereotactic magnetic resonance guided adaptive radiation therapy (SMART) is a new option for local treatment of unresectable pancreatic ductal adenocarcinoma, showing interesting survival and local control (LC) results. Despite this, some patients will experience early local and/or metastatic recurrence leading to death. We aimed to develop multiparametric prognostic models for these pat...

Development and validation of machine learning models for early diagnosis and prognosis of lung adenocarcinoma using miRNA expression profiles.

ObjectiveStudy aims to develop diagnostic and prognostic models for lung adenocarcinoma (LUAD) using Machine learning（ML）algorithms, aiming to enhance clinical decision-making accuracy.MethodsData from The Cancer Genome Atlas (TCGA) for LUAD patients were split into training (n = 196) and test sets (n = 133). Feature selection (Least Absolute Shrinkage and Selection Operator (LASSO), Random Forest...

Application of an Automated Deep Learning Program to A Diagnostic Classification Model: Differentiating High-Risk Adenomas Among Colorectal Polyps 10 mm or Smaller.

OBJECTIVE: This study aimed to develop a computer-aided diagnosis (CADx) model using an automated deep learning (DL) program to classify low- and high...

Metabolomic machine learning-based model predicts efficacy of chemoimmunotherapy for advanced lung squamous cell carcinoma.

BACKGROUND: Unlike lung adenocarcinoma, patients with advanced squamous carcinoma exhibit a low proportion of driver gene positivity, with fewer effec...

Predictive models of epidermal growth factor receptor mutation in lung adenocarcinoma using PET/CT-based radiomics features.

BACKGROUND: Lung adenocarcinoma (LAC) comprises a substantial subset of non-small cell lung cancer (NSCLC) diagnoses, where epidermal growth factor re...

A CNN-transformer fusion network for predicting high-grade patterns in stage IA invasive lung adenocarcinoma.

BACKGROUND: Invasive lung adenocarcinoma (LUAD) with the high-grade patterns (HGPs) has the potential for rapid metastasis and frequent recurrence. Th...

A Novel Natural Language Processing Tool Improves Colonoscopy Auditing of Adenoma and Serrated Polyp Detection Rates.

BACKGROUND AND STUDY AIMS: Determining adenoma detection rate (ADR) and serrated polyp detection rate (SDR) can be challenging as they usually involve...

Prediction of BRAF and TERT status in PTCs by machine learning-based ultrasound radiomics methods: A multicenter study.

BACKGROUND: Preoperative identification of genetic mutations is conducive to individualized treatment and management of papillary thyroid carcinoma (P...

Development and Multi-center validation of a machine learning Model for advanced colorectal neoplasms screening.

BACKGROUND: In colorectal cancer (CRC) screening programs, accurately identifying individuals at high risk for advanced colorectal neoplasia (ACN) is ...

Lung cancer detection and classification using optimized CNN features and Squeeze-Inception-ResNeXt model.

Lung cancer, with its high mortality rate, is one of the deadliest diseases globally. The alarming increase in lung cancer deaths and its widespread p...

Preoperative Prediction of STAS Risk in Primary Lung Adenocarcinoma Using Machine Learning: An Interpretable Model with SHAP Analysis.

BACKGROUND: Accurate preoperative prediction of spread through air spaces (STAS) in primary lung adenocarcinoma (LUAD) is critical for optimizing surg...

A tumor-infiltrating B lymphocytes -related index based on machine-learning predicts prognosis and immunotherapy response in lung adenocarcinoma.

INTRODUCTION: Tumor-infiltrating B lymphocytes (TILBs) play a pivotal role in shaping the immune microenvironment of tumors (TIME) and in the progress...

Automated classification of tertiary lymphoid structures in colorectal cancer using TLS-PAT artificial intelligence tool.

Colorectal cancer (CRC) ranks as the third most common and second deadliest cancer worldwide. The immune system, particularly tertiary lymphoid struct...

A fusion model to predict the survival of colorectal cancer based on histopathological image and gene mutation.

Colorectal cancer (CRC) is a prevalent gastrointestinal tumor worldwide with high morbidity and mortality. Predicting the survival of CRC patients not...

Development of PDAC diagnosis and prognosis evaluation models based on machine learning.

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is difficult to detect early and highly aggressive, often leading to poor patient prognosis. Exist...

Stroma and lymphocytes identified by deep learning are independent predictors for survival in pancreatic cancer.

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers known to humans. However, not all patients fare equally poor survival, and a...

Multimodal treatment of colorectal liver metastases: Where are we? Current strategies and future perspectives.

Despite the continued high prevalence of colorectal cancer in the Western world, recent years have witnessed a decline in its mortality rate, largely ...

A semi-supervised convolutional neural network for diagnosis of pancreatic ductal adenocarcinoma based on EUS-FNA cytological images.

BACKGROUND: The cytological diagnostic process of EUS-FNA smears is time-consuming and manpower-intensive, and the conclusion could be subjective and ...

Utility of comprehensive genomic profiling combined with machine learning for prognostic stratification in stage II/III colorectal cancer after adjuvant chemotherapy.

BACKGROUND AND PURPOSE: Accurate recurrence risk evaluation in patients with stage II and III colorectal cancer (CRC) remains difficult. Traditional h...

A multimodal framework for assessing the link between pathomics, transcriptomics, and pancreatic cancer mutations.

In Pancreatic Ductal Adenocarcinoma (PDAC), predicting genetic mutations directly from histopathological images using Deep Learning can provide valuab...