Infectious Disease

COVID-19

Latest AI and machine learning research in covid-19 for healthcare professionals.

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A novel multiplex detection array revealed systemic complement activation in oral squamous cell carcinoma.

Oral squamous cell carcinoma (OSCC) is one of the most common tumors within the oral cavity. Early diagnosis and prognosis tools are urgently needed. This study aimed to investigate the activation of the complement system in OSCC patients as potential biomarker. Therefore, an innovative complement activation array was developed. Characterized antibodies detecting the complement activation specific...

Dec 6 2017 29423024

Lateral flow immunoassay and enzyme linked immunosorbent assay as effective immunomethods for the detection of synthetic cannabinoid JWH-200 based on the newly synthesized hapten.

In recent years, the use of synthetic cannabinoids (SCs) as drugs of abuse has greatly increased. SCs are associated with a risk of severe poisoning or even death. Therefore, more rapid, cost effective and reliable methods are needed, especially for the screening of drivers after traffic accidents and for detailed toxicological analysis in forensic laboratories. In this study, we developed a later...

Dec 6 2017 29276691
Enhancement of lateral flow immunoassay by alkaline phosphatase: a simple and highly sensitive test for potato virus X.

Alkaline phosphatase (ALP) was used as an amplification tool in lateral flow immunoassay (LFIA). Potato virus Х (PVX) was selected as a target analyte...

Dec 6 2017 29594441
Evaluation of a human adenovirus viral load assay using the Altona RealStar® PCR test.

This study evaluated the performance of the Altona Diagnostics RealStar® Adenovirus Research Use Only (RUO) real-time PCR reagents for HAdV quantitati...

Dec 2 2017 29433999
Evaluation of fingerprinting techniques to assess genotype variation among Zygosaccharomyces strains.

Molecular typing techniques are key tools in surveillance of food spoilage yeasts, in investigations on intra-species population diversity, and in tra...

Dec 1 2017 29407390
Large-scale automated function prediction of protein sequences and an experimental case study validation on PTEN transcript variants.

Recent advances in computing power and machine learning empower functional annotation of protein sequences and their transcript variations. Here, we p...

Nov 29 2017 29098713
Infliximab trough levels and persistent vs transient antibodies measured early after induction predict long-term clinical remission in patients with inflammatory bowel disease.

BACKGROUND: The use of therapeutic drug monitoring has been proposed as a useful tool in the management of patients with loss of response to biologica...

Nov 27 2017 29274766
Sonochemical-solvothermal synthesis of guanine embedded copper based metal-organic framework (MOF) and its effect on oprD gene expression in clinical and standard strains of Pseudomonas aeruginosa.

The guanine incropped Cu based metal-organic framework (Guanine-Cu-MOF) was synthesized by facile one-step sonochemical method by simply mixing of 4-4...

Nov 26 2017 29429665
Effects of Interleukin-1 and -6 on the Expression of Ion Transporters Involved in Eggshell Mineralization in Cultured Hen Uterine Mucosal Tissue.

This study determined the effects of pro-inflammatory cytokines (interleukin (IL)-1 and IL-6) on the expression of eggshell mineralization-related ion...

Nov 25 2017 32055167
Self-enhanced PEI-Ru(II) complex with polyamino acid as booster to construct ultrasensitive electrochemiluminescence immunosensor for carcinoembryonic antigen detection.

In this work, the luminophor tris (4,4'-dicarboxylicacid-2,2'-bipyridyl) ruthenium (II) dichloride (Ru(dcbpy)) was linked to coreactant polyethylenimi...

Nov 22 2017 29291793
Dual-responsive electrochemical immunosensor for detection of insulin based on dual-functional zinc silicate spheres-palladium nanoparticles.

In this study, described an electrochemical immunoassay for insulin that is based on the use of zinc silicate spheres loaded with palladium nanopartic...

Nov 21 2017 29310254
A novel peptide/FeO@SiO-Au nanocomposite-based fluorescence biosensor for the highly selective and sensitive detection of prostate-specific antigen.

Highly selective and sensitive detection methods are very important for the early diagnosis of prostate-specific antigen (PSA). Here, we present a nov...

Nov 21 2017 29310271
An outbreak of classical swine fever in pigs in Bangladesh, 2015.

In a group of 22 healthy pigs aged between 4 and 6 months, 2 pigs became ill with high fever, complete anorexia, cough and abnormal swaying movements ...

Nov 20 2017 29468080
A deep auto-encoder model for gene expression prediction.

BACKGROUND: Gene expression is a key intermediate level that genotypes lead to a particular trait. Gene expression is affected by various factors incl...

Nov 17 2017 29219072
Enhancement of antibody-dependent cellular cytotoxicity of cetuximab by a chimeric protein encompassing interleukin-15.

Enhancement of antibody-dependent cellular cytotoxicity (ADCC) may potentiate the antitumor efficacy of tumor-targeted monoclonal antibodies. Increasi...

Nov 13 2017 29308327
Standardization of a latex agglutination test for coproantigen detection of sp. in bovine cattle stool.

Fasciolosis is a zoonotic parasitic disease, which affects humans and animals; diagnosed through noncommercial immunoassay tests that cannot be used o...

Nov 10 2017 29491560
Contaminant source identification using semi-supervised machine learning.

Identification of the original groundwater types present in geochemical mixtures observed in an aquifer is a challenging but very important task. Freq...

Nov 8 2017 29174719
Ruminal fermentation and microbial community differently influenced by four typical subtropical forages .

The present study evaluated the effects of 4 typical subtropical forages on ruminal microbial community composition to formulate a better diet for buf...

Nov 2 2017 30167491
Chemiluminescence based immunoassay for the detection of heroin and its metabolites.

Continuous use of opiates causes drug-related illnesses, which poses an alarming situation to develop sensitive detection platform. In this study, a ...

Oct 30 2017 29713602
Lupus pneumonitis presenting with high titre of anti-Ro antibody.

Lupus pneumonitis carries high mortality and is a rare manifestation of systemic lupus erythematosus (SLE). However, it is difficult to diagnose and i...

Oct 27 2017 29321925
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