Neurology

Dementia

Latest AI and machine learning research in dementia for healthcare professionals.

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Assessing racial disparities in dementia-related vulnerabilities: a machine learning analysis of social, environmental, and climate factors.

INTRODUCTION: Racial differences in exposure to area-level social determinants of health (SDoH) may contribute to distinct vulnerability profiles among people living with dementia. METHODS: This cross-sectional study used data from the OCHIN Community Health Equity Database to examine SDoH factors among patients with dementia and mild cognitive impairment. SDoH measures encompassed social, environ...

Apr 8 2026 41952418

Drug repurposing in Alzheimer's disease: Emerging therapeutic strategies and promising candidates.

Alzheimer's disease is a progressive neurodegenerative disorder, and the most common cause of dementia, which causes 60-70 % of cases worldwide, and its prevalence is increasing by more than 55 million people globally, with an expected increase of 139 million cases by 2050. AD is characterized by Amyloid-β plaque deposition, tau hyperphosphorylation, synaptic dysfunction, neuroinflammation, and ox...

Apr 7 2026 41956136
Real-World Data From a Group Parent Management Training Program Enhanced Using Artificial Intelligence: Qualitative Study.

BACKGROUND: Parent management training (PMT) is an evidence-based intervention for children with disruptive behavior problems. However, access to care...

Apr 7 2026 41945899
Voice Biomarkers: Cognitive Impairment, including Alzheimer's Disease, Dementia, or Mild Cognitive Impairment: Introduction to Peripheral Neuropathy.

INTRODUCTION/OBJECTIVE: Alzheimer's disease (AD) can cause certain nervous disorders, which in turn can lead to voice disorders and abnormal values fo...

Apr 6 2026 41944116
Cognitive health on the fingertips: Fine motor deficiencies for assessing the risk of mild cognitive impairment in the aging adults.

OBJECTIVE: Mild cognitive impairment (MCI) represents a critical prodromal stage associated with Alzheimer's disease and other age-related neurocognit...

Apr 6 2026 41941131
AI-Enhanced Automatic Life Story Structuring for Reminiscence Therapy in Older Adults: Technical Feasibility Study.

BACKGROUND: Storytelling interventions have demonstrated substantial potential in improving emotional well-being, cognitive function, and quality of l...

Apr 6 2026 41941365
Alzheimer's disease staging using enhanced inception-ResNet-V2 and improved XceptionNet models for 3D MRI classification and segmentation.

BACKGROUND: Neurologists have a significant challenge due to the progressive nature of Alzheimer's disease (AD) and its severe effects on cognitive fu...

Apr 5 2026 41941947
LADNET: An MRI-based deep learning approach for Alzheimer's disease detection.

Alzheimer's disease (AD) is considered a leading form of dementia, found in the majority of individuals, and it accounts for the highest prevalence of...

Apr 4 2026 41936289
CRISPR-Cas9 and next-generation gene editing strategies for therapeutic intervention of neurodegenerative pathways in Alzheimer's disease: a state-of-the-art review.

Alzheimer's disease (AD) is a progressive and multifactorial neurodegenerative disorder and the leading cause of dementia worldwide, characterized by ...

Apr 3 2026 41931258
A longitudinal and explainable 2.5D deep learning framework for Alzheimer's disease progression using ADNI MRI.

Early identification of Alzheimer's disease (AD) and its prodromal stage, mild cognitive impairment (MCI), is important for timely clinical assessment...

Apr 2 2026 42005278
Adult Day Centers as Partners in Baccalaureate Nursing Dementia Education.

This pilot study explored how adult day centers can serve as transformative clinical learning environments for nursing students to learn dementia care...

Apr 2 2026 41925309
Advancing diagnostic biomarkers in Alzheimer's disease: interdisciplinary innovations and technological frontiers.

Developing diagnostic biomarkers for Alzheimer's disease (AD) is at the cutting edge of interdisciplinary research and technical advancement. This com...

Apr 2 2026 41925947
AI-Driven Multimodal Analysis of Neuroimaging and Speech Data for Diagnosis of Alzheimer's, Parkinson's, and Epilepsy.

This study investigates the application of machine learning (ML) techniques combined with neuroimaging and speech signal processing for the early dete...

Apr 1 2026 41918394
Eye movement features are associated with cognitive and mobility decline.

BackgroundEye movement is a vital indicator of neurodegenerative diseases, brain health, and behavior. However, existing knowledge is limited to patie...

Apr 1 2026 41919773
Focal-DenseNet: A Risk Assessment Framework for Alzheimer's Disease in Heterogeneous MRI Data.

Alzheimer's disease (AD) is a progressive neurodegenerative disease of the nervous system, which has become an important public health issue attractin...

Apr 1 2026 41920507
Development and Validation of Machine Learning Models for Predicting Early Cognitive Decline Using Home Sensor-Derived Behavioral Data: Sensors in-Home for Elder Wellbeing (SINEW) Cohort Study.

BACKGROUND: As the global population continues to age, the prevalence of geriatric conditions, including dementia and frailty, is also increasing. Ear...

Apr 1 2026 41921108
Artificial intelligence for educating family caregivers of people with dementia: A mixed methods systematic review.

Dementia is a growing global health challenge, with the majority of individuals living with dementia receiving care from family members. However, many...

Apr 1 2026 41926851
OPTIMUS: Predicting Multivariate Outcomes in Alzheimer's Disease Using Multi-Modal Data Amidst Missing Values.

OBJECTIVE: Alzheimer's disease, a progressive neurodegenerative disorder, involves neural, genetic, and proteomic factors and impacts multiple cogniti...

Apr 1 2026 40932805
From Cultural Context to System Resilience: Advancing Global Mental Health for Older Adults.

Population aging worldwide has intensified the need to understand how mental health in later life is shaped by both cultural norms and structural syst...

Apr 1 2026 41763872
Design and Development of an Automated Electroencephalogram Signal Processing and Diagnostic Support Architecture Employing Advanced Deep Learning Models for Early Accurate and Scalable Detection of Neurological Diseases.

BACKGROUND AND PURPOSE: Electroencephalogram (EEG) signals play a vital role in analyzing neurological activity and diagnosing various neurological di...

Apr 1 2026 41902307
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