Dementia

Cost-Sensitive Weighted Contrastive Learning Based on Graph Convolutional Networks for Imbalanced Alzheimer's Disease Staging.

Identifying the progression stages of Alzheimer's disease (AD) can be considered as an imbalanced multi-class classification problem in machine learning. It is challenging due to the class imbalance issue and the heterogeneity of the disease. Recently, graph convolutional networks (GCNs) have been successfully applied in AD classification. However, these works did not handle the class imbalance is...

Regression convolutional neural network models implicate peripheral immune regulatory variants in the predisposition to Alzheimer's disease.

Alzheimer's disease (AD) involves aggregation of amyloid β and tau, neuron loss, cognitive decline, and neuroinflammatory responses. Both resident microglia and peripheral immune cells have been associated with the immune component of AD. However, the relative contribution of resident and peripheral immune cell types to AD predisposition has not been thoroughly explored due to their similarity in ...

Deep learning-based segmentation in MRI-(immuno)histological examination of myelin and axonal damage in normal-appearing white matter and white matter hyperintensities.

The major vascular cause of dementia is cerebral small vessel disease (SVD). Its diagnosis relies on imaging hallmarks, such as white matter hyperinte...

Effect of a Group-Based Personal Assistive RObot (PARO) Robot Intervention on Cognitive Function, Autonomic Nervous System Function, and Mental Well-being in Older Adults with Mild Dementia: A Randomized Controlled Trial.

OBJECTIVES: Personal Assistive RObot (PARO) interventions have been used to treat agitation and mood symptoms of dementia effectively. However, the ef...

PVTAD: ALZHEIMER'S DISEASE DIAGNOSIS USING PYRAMID VISION TRANSFORMER APPLIED TO WHITE MATTER OF T1-WEIGHTED STRUCTURAL MRI DATA.

Alzheimer's disease (AD) is a neurodegenerative disorder, and timely diagnosis is crucial for early interventions. AD is known to have disruptive loca...

An efficient ANN SoC for detecting Alzheimer's disease based on recurrent computing.

Alzheimer's Disease (AD) is an irreversible, degenerative condition that, while incurable, can have its progression slowed or impeded. While there are...

A minimalistic approach to classifying Alzheimer's disease using simple and extremely small convolutional neural networks.

BACKGROUND: There is a broad interest in deploying deep learning-based classification algorithms to identify individuals with Alzheimer's disease (AD)...

Machine learning quantification of Amyloid-β deposits in the temporal lobe of 131 brain bank cases.

Accurate and scalable quantification of amyloid-β (Aβ) pathology is crucial for deeper disease phenotyping and furthering research in Alzheimer Diseas...

Use of machine learning algorithms to determine the relationship between air pollution and cognitive impairment in Taiwan.

Air pollution has become a major global threat to human health. Urbanization and industrialization over the past few decades have increased the air po...

Improved Dementia Prediction in Cerebral Small Vessel Disease Using Deep Learning-Derived Diffusion Scalar Maps From T1.

BACKGROUND: Cerebral small vessel disease is the most common pathology underlying vascular dementia. In small vessel disease, diffusion tensor imaging...

Revolutionizing early Alzheimer's disease and mild cognitive impairment diagnosis: a deep learning MRI meta-analysis.

BACKGROUND:  The early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI) remains a significant challenge in neurology, with co...

Metabolic dysfunctions predict the development of Alzheimer's disease: Statistical and machine learning analysis of EMR data.

INTRODUCTION: The incidence of Alzheimer's disease (AD) and obesity rise concomitantly. This study examined whether factors affecting metabolism, race...

Incremental Value of Multidomain Risk Factors for Dementia Prediction: A Machine Learning Approach.

OBJECTIVE: The current evidence regarding how different predictor domains contributes to predicting incident dementia remains unclear. This study aims...

Significance of plasma p-tau217 in predicting long-term dementia risk in older community residents: Insights from machine learning approaches.

INTRODUCTION: Whether plasma biomarkers play roles in predicting incident dementia among the general population is worth exploring.

TS-AI: A deep learning pipeline for multimodal subject-specific parcellation with task contrasts synthesis.

Accurate mapping of brain functional subregions at an individual level is crucial. Task-based functional MRI (tfMRI) captures subject-specific activat...

Mapping Knowledge Landscapes and Emerging Trends in AI for Dementia Biomarkers: Bibliometric and Visualization Analysis.

BACKGROUND: With the rise of artificial intelligence (AI) in the field of dementia biomarker research, exploring its current developmental trends and ...

Ensemble Deep Random Vector Functional Link Network Using Privileged Information for Alzheimer's Disease Diagnosis.

Alzheimer's disease (AD) is a progressive brain disorder. Machine learning models have been proposed for the diagnosis of AD at early stage. Recently,...

A Multi-Classification Accessment Framework for Reproducible Evaluation of Multimodal Learning in Alzheimer's Disease.

Multimodal learning is widely used in automated early diagnosis of Alzheimer's disease. However, the current studies are based on an assumption that d...

Graph Embedded Ensemble Deep Randomized Network for Diagnosis of Alzheimer's Disease.

Randomized shallow/deep neural networks with closed form solution avoid the shortcomings that exist in the back propagation (BP) based trained neural ...

A Cascaded Mutliresolution Ensemble Deep Learning Framework for Large Scale Alzheimer's Disease Detection Using Brain MRIs.

Alzheimer's is progressive and irreversible type of dementia, which causes degeneration and death of cells and their connections in the brain. AD wors...