Endocrinology

Latest AI and machine learning research in endocrinology for healthcare professionals.

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Showing 81-100 of 7,590 articles

Artificial Intelligence-Assisted Screening for Patients With Diabetic Retinopathy and Age-Related Macular Degeneration in Family Medicine and Geriatric and Gerontology Care: Protocol for a Pragmatic Randomized Clinical Trial.

BACKGROUND: Diabetic retinopathy (DR) and age-related macular degeneration (AMD) are 2 of the leading causes of vision loss worldwide. As population aging and diabetes prevalence increase, timely detection of these conditions has become essential. However, limited professionalism and insufficient training in ophthalmic screening among general medicine physicians may lead to delayed diagnosis and t...

Jul 6 2026 42406913

Identifying critical period of type 2 diabetes in Chinese population with leading molecules based on dynamic network biomarkers.

Diabetes has become a significant global public health challenge, and prediabetes (preD), as the earliest detectable stage of glucose metabolism disorder, constitutes a critical window for disease intervention. Currently, China has not established diagnostic criteria for HbA1c in preD, and there is limited understanding of the molecular mechanisms at the critical transition points during disease p...

Jul 6 2026 42409956
Identification of candidate genes and metabolites associated with lactation performance in Kazakh mares using blood multi-omics and machine learning.

BACKGROUND: The Kazakh mare, an indigenous breed of Xinjiang, exhibits strong adaptability to arid and cold conditions while maintaining relatively st...

Jul 6 2026 42410339
Comprehensive and low-cost machine learning models for predicting MASLD prevalence: cross-sectional evidence from the amol cohort study (AmolCS).

Metabolic dysfunction-associated steatotic liver disease (MASLD) represents a growing global health burden, yet early detection remains difficult, esp...

Jul 6 2026 42410493
A Unified Molecular Graph and Protein Language Model Framework for Predicting Human Drug-Hormone Receptor Interactions with Structure-Aware Validation.

Hormones regulate many essential biological processes by interacting with specific receptors that control gene expression, metabolism, growth, and imm...

Jul 5 2026 42402023
Interpretable deep learning to predict one year glycemic control in type 1 diabetes using real world data.

Type 1 diabetes (T1D) involves long-term health risks and challenges in individualizing therapeutic strategies. Meeting glycemic targets is a reliable...

Jul 4 2026 42401631
PCOSFusion: a hybrid HOG-LBP feature-based approach for PCOS classification using StackPCOS and StackBoostPCOS.

Polycystic Ovary Syndrome (PCOS) is a prevalent condition affecting female reproductive health, where early and accurate detection through image analy...

Jul 4 2026 42401681
Association between glucose-to-platelet ratio and all-cause mortality in critically ill patients with acute myocardial infarction: a retrospective cohort study.

BACKGROUND: Acute myocardial infarction (AMI) in critically ill patients is associated with high mortality. The glucose-to-platelet ratio (GPR), deriv...

Jul 4 2026 42401828
Multi-omics integration identifies macrophage senescence driven by the RUNX1-P53 axis as a key mechanism in diabetic foot ulcer.

Diabetic foot ulcer (DFU) is a severe complication of diabetes, characterized by chronic inflammation and impaired healing. Although cellular and immu...

Jul 4 2026 42399485
Perioperative prediction of adnexal malignancy by an interpretable machine learning model for guiding ovarian preservation in premenopausal endometrial cancer.

BACKGROUND: Ovarian preservation in premenopausal patients with endometrial cancer remains challenging due to the potential presence of concurrent adn...

Jul 3 2026 42400061
Sex Hormone Receptors, HBV Integrations and Their Prognostic Predictive Value Among Hepatocellular Carcinoma Patients.

Hepatocellular carcinoma (HCC) related to hepatitis B virus (HBV) infection predominantly affects males, yet few studies have investigated the associa...

Jul 3 2026 42400106
The application of artificial intelligence in adrenal imaging: current state of knowledge, challenges, and future directions.

Adrenal incidentalomas are frequently detected on abdominal imaging and require evaluation for malignancy and hormonal activity. Although most are ben...

Jul 3 2026 42396958
Metabolomic signature reveals dysregulated lipoprotein profile in m.3243A>G carriers: a case-control study.

INTRODUCTION: The pathogenic mitochondrial gene variant m.3243A>G disrupts oxidative phosphorylation and is associated with insulin resistance, both o...

Jul 3 2026 42397637
Development of a predictive model for postoperative body mass index and diabetes outcomes after metabolic bariatric surgery: retrospective cohort study.

BACKGROUND: Predicting postoperative body mass index (BMI) trajectories and long-term type 2 diabetes (T2D) remission after bariatric surgery remains ...

Jul 3 2026 42398077
Prediction of Type 2 Diabetes Mellitus From Chest X-Rays Using a Suite of Previously Developed Chronic Disease Deep Learning Models in an Ethnically Diverse Cohort: Observational Study.

BACKGROUND: Screening for type 2 diabetes (T2D) is not optimal, leading to a large number of patients being undiagnosed. Recently, deep learning (DL) ...

Jul 3 2026 42398923
Artificial intelligence-powered surgical scene analysis in minimally invasive adrenal surgery: integrated recognition of anatomy, tools and phases.

BACKGROUND: This retrospective feasibility study aimed to develop an artificial intelligence-powered surgical model capable of recognizing key anatomi...

Jul 2 2026 42390781
A Validated, Modifiable Proteomic Score from the EXSCEL Trial Predicts Cardiovascular Events in Diabetes.

Adults with type 2 diabetes mellitus (T2DM) are at increased risk for stroke, myocardial infarction, and cardiovascular death, yet individual risk is ...

Jul 2 2026 42390946
AI-augmented thyroid scintigraphy for robust classification of disease.

Thyroid scintigraphy is vital for diagnosing thyroid disorders, yet deep learning (DL) models in this domain often struggle with limited, imbalanced d...

Jul 2 2026 42391725
A digital marker for stratifying cardiovascular metabolic comorbidities among the middle-aged and elderly adults.

Cardiovascular Metabolic Comorbidities (CMM) share common physiological mechanisms in inflammation and immunity, oxidative stress, and insulin resista...

Jul 2 2026 42391238
Key molecular mechanisms of mitochondrial metabolic pathways in specific cell subpopulations of pancreatic cancer based on scRNA-seq and bulk RNA-seq.

BACKGROUND: Pancreatic cancer (PC) is a highly malignant tumor with increasing incidence, mortality, and a low five-year survival rate. Mitochondrial ...

Jul 2 2026 42391245
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