Infectious Disease

Flu & URI

Latest AI and machine learning research in flu & uri for healthcare professionals.

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Language models learn to represent antigenic properties of human influenza A(H3) virus

Given that influenza vaccine effectiveness depends on a good antigenic match between the vaccine and...

CoV-UniBind: A Unified Antibody Binding Database for SARS-CoV-2

Since the emergence of SARS-CoV-2, numerous studies have investigated antibody interactions with vir...

WaveSeekerNet: Accurate Prediction of Influenza A Virus Subtypes and Host Source Using Attention-Based Deep Learning

Influenza A virus (IAV) poses a significant threat to animal health globally, with its ability to ov...

Mapping antigenic evolution of influenza A virus using deep learning-based prediction of hemagglutination inhibition titers

Seasonal influenza remains a significant public health challenge through unpredictable antigenic dri...

Reengineering the antigen optimization process for superior neoantigen vaccine design

Identifying effective neoantigen sequences is essential for enhancing anti-tumor immunity. However, ...

From sequence to scaffold: computational design of protein nanoparticle vaccines from AlphaFold2-predicted building blocks

Self-assembling protein nanoparticles are being increasingly utilized in the design of next-generati...

APDeeM: A machine Learning strategy towards Effective Peptide Vaccine Candidates Identification against Different Types of Viruses

Viral infections pose significant global health challenges, underscoring the urgent need for improve...

Decoding the interconnected splicing patterns of hepatitis B virus and host using large language and deep learning models

Hepatitis B virus (HBV) infection causes approximately one million deaths annually and remains a maj...

Influ-BERT: A Domain-Adaptive Genomic Language Model for Advancing Influenza A Virus Research

Influenza A Virus (IAV) poses a persistent threat to global public health due to its broad host adap...

T-SCAPE: T-cell Immunogenicity Scoring via Cross-domain Aided Predictive Engine

T-cell immunogenicity, the ability of peptide fragments to elicit T-cell responses, is a critical de...

Machine Learning Enables Viral Genome-Agnostic Classification of RNA Virus Infections from Host Transcriptomes

Targeted PCR diagnosis of RNA viruses is sequence dependent, meaning that the accuracy of the assay ...

Hollow-fibre biomanufacturing and cell-free engineering of HEK293 extracellular vesicles

Extracellular vesicles (EVs) are lipid-delineated nanoparticles that are produced by most cell types...

Deep Generative Optimization of mRNA Codon Sequences for Enhanced mRNA Translation and Therapeutic Efficacy

Messenger RNA (mRNA) therapeutics show immense promise, but their efficacy is limited by suboptimal ...

An AI for an AI: identifying zoonotic potential of avian influenza viruses via genomic machine learning

Avian influenza remains a serious risk to human health via zoonotic transmission, as well as a feasi...

An Immuno-Linguistic Transformer for Multi-Scale Modeling of T-Cell Spatiotemporal Dynamics

Understanding the spatiotemporal dynamics of T-cell clones is a critical challenge in immunology and...

A study on edge devices for image classification of the Tasmanian devil (Sarcophilus harrisii) for vaccine delivery

A target-specific bait dispenser is required for oral bait vaccination of the endangered Tasmanian d...

Multivariate analysis of glycogenes reveals coordinated regulation of immunoglobulin glycosylation in an immortalized human B cell system

While neutralizing ability has traditionally been considered the most important antibody function, a...

Benchmarking Large Language Models for Pathogen–Disease Classification in Post-Acute Infection Syndromes

Post-Acute Infection Syndromes (PAIS) are medical conditions that persist following acute infections...

Iterative immunogen optimization to focus immune responses on a conserved, subdominant viral epitope

Designing effective vaccination strategies against genetically diverse viruses, such as HIV or influ...

Predicting Future SARS-CoV-2 Mutations using Deep Learning

SARS-CoV-2 continues to spread over the world steadily as opposed to many earlier estimations that i...

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