Fungal Infection

Integrated machine learning, molecular docking and 3D-QSAR based approach for identification of potential inhibitors of trypanosomal N-myristoyltransferase.

N-Myristoyltransferase (NMT) catalyzes the transfer of myristate to the amino-terminal glycine of a subset of proteins, a co-translational modification involved in trafficking substrate proteins to membrane locations, stabilization and protein-protein interactions. It is a studied and validated pre-clinical drug target for fungal and parasitic infections. In the present study, a machine learning a...

Comparison of aglycon and glycosidic saponin extracts of tuber against spp.

BACKGROUND AND PURPOSE: Candidiasis, an important fungal infection, is considered the fourth most common nosocomial blood stream infection. Nowadays, because of increased fungal resistance to antibiotics, the use of herbal medicine has gained particular attention. species are medicinal plants containing triterpenoid saponins, which are shown to have antimicrobial properties.

An Evaluation on Different Machine Learning Algorithms for Classification and Prediction of Antifungal Peptides.

BACKGROUND: Fungi are an emerging threat in medicine and agriculture and current therapeutics have proved to be insufficient and toxic. This has led t...

ANTIFUNGAL ACTIVITY OF Cymbopogon nardus (L.) Rendle (CITRONELLA) AGAINST Microsporum canis FROM ANIMALS AND HOME ENVIRONMENT.

Dermatophytosis is a common zoonosis in urban centers. Dogs and cats have played an important role as its disseminators. Environmental decontamination...

Screening of Xylanolytic for Prebiotic Xylooligosaccharide Production Using Bagasse.

Sugarcane bagasse is an important lignocellulosic material studied for the production of xylooligosaccharides (XOS). Some XOS are considered soluble d...

[Analysis of Cases with Elevated Blood (1->3)-β-D-glucan in Relation to an Infection Marker, Neutrophil CD64 Expression].

(1->3)-β-D-glucan (BDG) is a constituent of the fungal cell wall and its blood level is known as a marker of fungal infection including pneumocystis p...

Nitric Oxide Production Inhibition and Anti-Mycobacterial Activity of Extracts and Halogenated Sesquiterpenes from the Brazilian Red Alga Laurencia Dendroidea J. Agardh.

BACKGROUND: Red algae of the genus Laurencia J. V. Lamouroux are a rich source of secondary metabolites with important pharmacological activities such...

[Screening and identification of antioxidant endophytes from Lycium barbarum of Ningxia].

In this paper, 29 endophytes were isolated from different organs and tissues of Lycium barbarum of Ningxia by tablet coating method, 18 of them was fu...

Automatic identification of fungi under complex microscopic fecal images.

Automatic identification of fungi in microscopic fecal images provides important information for evaluating digestive diseases. To date, disease diagn...

Use of an Artificial Neural Network to Construct a Model of Predicting Deep Fungal Infection in Lung Cancer Patients.

BACKGROUND: The statistical methods to analyze and predict the related dangerous factors of deep fungal infection in lung cancer patients were several...

Managing changes in distributed biomedical ontologies using hierarchical distributed graph transformation.

The issue of ontology evolution and change management is inadequately addressed by available tools and algorithms, mostly due to the lack of suitable ...