Gastroenterology

Latest AI and machine learning research in gastroenterology for healthcare professionals.

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The Addition of Computer-Aided Detection (CADe) to Texture and Color Enhancement Imaging (TXI) Does Not Improve Adenoma Detection Rate During Colonoscopy: A Prospective Study.

OBJECTIVES: Early detection and resection of colorectal polyps prevent their progression toward advanced adenocarcinomas. The use of Texture and Color Enhancement Imaging (TXI) has been demonstrated to enhance adenoma detection compared to white light imaging. It remains unknown whether there is an additive benefit when using computer-aided detection (CADe) in addition to enhanced imaging technolo...

Jun 26 2026 42363424

Integrative analysis of machine learning and single-cell sequencing identifies IGHG1 as a therapeutic target for epimedium in diabetes-gastric cancer comorbidity.

BACKGROUND: The clinical comorbidity of diabetes mellitus (DM) and gastric cancer (GC) presents a significant healthcare challenge, as these two conditions often synergistically promote disease progression. Although Epimedium is known for its anti-tumor and metabolic regulatory properties, the precise molecular mechanism by which it intervenes in the DM-GC comorbidity remains poorly understood. ME...

Jun 26 2026 42364318
Radiation scatter at fluoroscopy-guided endoscopic procedures: Building towards further optimization.

INTRODUCTION: Exposure to ionizing radiation by endoscopy personnel during fluoroscopy-guided procedures remains a health hazard. We aimed to evaluate...

Jun 26 2026 42358121
A Physics-Informed Deep Learning Framework for Estimating Muscle Activation Patterns Following Achilles Tendon Repair.

Accurate soleus (SOL) activation assessment is essential for Achilles tendon rupture (ATR) recovery, yet direct measurement remains a clinical challen...

Jun 26 2026 42359776
Disulfidptosis-related signatures identify SPARC+/CYR61+ stromal cells mediating immunosuppression in gastric cancer.

BACKGROUND: Disulfidptosis is a novel form of glucose starvation-induced cell death, yet its prognostic implications in gastric cancer (GC) remain lar...

Jun 26 2026 42360660
SMURF: soft-segmentation for single-cell reconstruction and topological analysis of spatial transcriptomic data.

High-resolution spatial transcriptomics requires computational methods to accurately assign transcripts to individual cells. We present SMURF (Segment...

Jun 26 2026 42350392
[Computational medicine empowers multi-dimensional diagnosis and treatment of pancreatic cancer].

Due to its high genomic heterogeneity and dense desmoplastic microenvironment, traditional diagnosis and treatment for pancreatic ductal adenocarcinom...

Jun 26 2026 42350889
[Arterial variations and management strategies in pancreatic surgery].

The pancreas is local in the retroperitoneal space,in close proximity to critical blood vessels such as celiac trunk, superior mesenteric artery, hepa...

Jun 26 2026 42350891
[A two-stage model for predicting postoperative pulmonary infection in esophageal cancer patients].

Postoperative pulmonary infection (PPI) after esophageal cancer surgery occurs frequently and severely impairs patients' prognosis. Most existing pred...

Jun 25 2026 42366437
Review Article: Advances in the Diagnosis of Dysplasia in Barrett's Oesophagus.

BACKGROUND: Barrett's oesophagus (BE), the precursor to oesophageal adenocarcinoma, progresses through a stepwise dysplastic sequence. Accurate dyspla...

Jun 25 2026 42351305
Implementation of a prospective video databank for artificial intelligence model development, validation and clinical outcomes research in gastrointestinal endoscopy.

BACKGROUND AND AIMS: High-quality, annotated datasets are fundamental to clinical research and artificial intelligence (AI) model development. Existin...

Jun 25 2026 42349759
Novel genetic insights into causal effects of depression on non-alcoholic fatty liver diseases partially mediated by gut microbiota.

Depression and non-alcoholic fatty liver disease (NAFLD) are increasingly recognized as interconnected disorders, yet the causal mechanisms linking th...

Jun 25 2026 42349829
Diagnosis of Small Focal Liver Lesions (≤2 cm): A Deep Learning Approach Based on B-Mode Ultrasound and Contrast-Enhanced Ultrasound.

BACKGROUND: To develop and validate a deep learning (DL) model based on feature fusion with B-mode ultrasound (BMUS) and contrast enhanced ultrasound ...

Jun 25 2026 42350195
A prediction model based on tumor immune microenvironment for immunotherapy response in gastric cancer.

This study aimed to develop a robust prediction model- using machine-learning algorithms based on the core indicators of the tumor immune microenviron...

Jun 25 2026 42350633
A bibliometric analysis of research trends and future directions in early detection of pancreatic cancer.

BACKGROUND: Research on the early detection of pancreatic cancer has grown rapidly in recent years; however, existing bibliometric studies in this fie...

Jun 25 2026 42350705
Deep learning-driven MRI radiomics reveals biological subtypes and predicts recurrence risk in rectal cancer.

Traditional TNM staging inadequately captures the recurrence risk of rectal cancer (RC), limiting prognostic accuracy and personalized treatment decis...

Jun 25 2026 42350713
An interpretable XGboost algorithm for predicting 30-day mortality in acute pancreatitis using routine biomarkers.

OBJECTIVE: To develop and validate a machine learning (ML) algorithm for predicting 30-day mortality in adult patients with acute pancreatitis (AP) us...

Jun 25 2026 42350973
Selection of proper artificial intelligence techniques developed for CT scan image analysis of liver cancer using fuzzy AHP-TOPSIS.

OBJECTIVE: Comprehensive identification and prioritization of developed artificial intelligence methods for applications of radiology can help to sele...

Jun 25 2026 42351048
Development and pilot evaluation of a large language model-based clinical simulation system for medical education in gastroenterology.

BACKGROUND: Medical education relies on experience to develop clinical reasoning skills, yet patient access is often limited. Large language models (L...

Jun 25 2026 42351097
Dynamic gut microbiota shift in chronic liver disease progression: machine learning models and the E/Er ratio as a predictive biomarker.

BACKGROUND: Chronic liver disease (CLD) and its progression to compensated cirrhosis (CC), decompensated cirrhosis (DC), and acute-on-chronic liver fa...

Jun 25 2026 42351186
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