Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Rewireable Building Blocks for Enzyme-Powered DNA Computing Networks.

Neural networks enable the processing of large, complex data sets with applications in disease diagn...

Sep 2024 39255470
Integrating large-scale single-cell RNA sequencing in central nervous system disease using self-supervised contrastive learning.

The central nervous system (CNS) comprises a diverse range of brain cell types with distinct functio...

Sep 2024 39251817
Aging-related biomarkers for the diagnosis of Parkinson's disease based on bioinformatics analysis and machine learning.

Parkinson's disease (PD) is a multifactorial disease that lacks reliable biomarkers for its diagnosi...

Sep 2024 39264583
Exploring the interplay between colorectal cancer subtypes genomic variants and cellular morphology: A deep-learning approach.

Molecular subtypes of colorectal cancer (CRC) significantly influence treatment decisions. While con...

Sep 2024 39255280
Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy.

Understanding the interplay between the HIV reservoir and the host immune system may yield insights ...

Sep 2024 39250423
Development of a prognostic model for NSCLC based on differential genes in tumour stem cells.

Non-small cell lung cancer (NSCLC) constitutes a significant portion of lung cancers and cytotoxic d...

Sep 2024 39251710
Machine learning supported single-stranded DNA sensor array for multiple foodborne pathogenic and spoilage bacteria identification in milk.

Ensuring food safety through rapid and accurate detection of pathogenic bacteria in food products is...

Sep 2024 39265300
Predictive biomarkers for embryotoxicity: a machine learning approach to mitigating multicollinearity in RNA-Seq.

Multicollinearity, characterized by significant co-expression patterns among genes, often occurs in ...

Sep 2024 39242367
Plasma cell-free RNA signatures of inflammatory syndromes in children.

Inflammatory syndromes, including those caused by infection, are a major cause of hospital admission...

Sep 2024 39240972
A hybrid residue based sequential encoding mechanism with XGBoost improved ensemble model for identifying 5-hydroxymethylcytosine modifications.

RNA modifications play an important role in actively controlling recently created formation in cellu...

Sep 2024 39242695
Diagnostic classification based on DNA methylation profiles using sequential machine learning approaches.

Aberrant methylation patterns in human DNA have great potential for the discovery of novel diagnosti...

Sep 2024 39240881
A machine-learning based model for automated recommendation of individualized treatment of rifampicin-resistant tuberculosis.

BACKGROUND: Rifampicin resistant tuberculosis remains a global health problem with almost half a mil...

Sep 2024 39241084
A machine learning approach for rapid early detection of Campylobacter spp. using absorbance spectra collected from enrichment cultures.

Enumeration of Campylobacter from environmental waters can be difficult due to its low concentration...

Sep 2024 39241091
Improving viral annotation with artificial intelligence.

Viruses of bacteria, "phages," are fundamental, poorly understood components of microbial community ...

Sep 2024 39230289
Integrating Deep Learning and Synthetic Biology: A Co-Design Approach for Enhancing Gene Expression via N-Terminal Coding Sequences.

N-terminal coding sequence (NCS) influences gene expression by impacting the translation initiation ...

Sep 2024 39229974
m5C-Seq: Machine learning-enhanced profiling of RNA 5-methylcytosine modifications.

Epigenetic modifications, particularly RNA methylation and histone alterations, play a crucial role ...

Sep 2024 39232403
Probing Nanotopography-Mediated Macrophage Polarization via Integrated Machine Learning and Combinatorial Biophysical Cue Mapping.

Inflammatory responses, leading to fibrosis and potential host rejection, significantly hinder the l...

Sep 2024 39226301
Joint trajectory inference for single-cell genomics using deep learning with a mixture prior.

Trajectory inference methods are essential for analyzing the developmental paths of cells in single-...

Sep 2024 39226366
Low-pass whole genome sequencing of circulating tumor cells to evaluate chromosomal instability in triple-negative breast cancer.

Chromosomal Instability (CIN) is a common and evolving feature in breast cancer. Large-scale Transit...

Sep 2024 39227622
Deep neural networks integrating genomics and histopathological images for predicting stages and survival time-to-event in colon cancer.

MOTIVATION: There exists an unexplained diverse variation within the predefined colon cancer stages ...

Sep 2024 39226289
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