Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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The Coming of Age of AI/ML in Drug Discovery, Development, Clinical Testing, and Manufacturing: The FDA Perspectives.

Artificial intelligence (AI) and machine learning (ML) represent significant advancements in computi...

Sep 2023 37701048
Coot-Lion optimized deep learning algorithm for COVID-19 point mutation rate prediction using genome sequences.

In this study, a deep quantum neural network (DQNN) based on the Lion-based Coot algorithm (LBCA-bas...

Sep 2023 37668061
Harnessing deep learning for population genetic inference.

In population genetics, the emergence of large-scale genomic data for various species and population...

Sep 2023 37666948
scTIGER: A Deep-Learning Method for Inferring Gene Regulatory Networks from Case versus Control scRNA-seq Datasets.

Inferring gene regulatory networks (GRNs) from single-cell RNA-seq (scRNA-seq) data is an important ...

Aug 2023 37686146
Prediction of DNA Methylation based on Multi-dimensional feature encoding and double convolutional fully connected convolutional neural network.

DNA methylation takes on critical significance to the regulation of gene expression by affecting the...

Aug 2023 37639434
ProS-GNN: Predicting effects of mutations on protein stability using graph neural networks.

Predicting protein stability change upon variation through a computational approach is a valuable to...

Aug 2023 37643501
Automated prognosis of renal function decline in ADPKD patients using deep learning.

An accurate prognosis of renal function decline in Autosomal Dominant Polycystic Kidney Disease (ADP...

Aug 2023 37612178
Predicting transcriptional outcomes of novel multigene perturbations with GEARS.

Understanding cellular responses to genetic perturbation is central to numerous biomedical applicati...

Aug 2023 37592036
Cytogenetics and genomics in pediatric acute lymphoblastic leukaemia.

The last five decades have witnessed significant improvement in diagnostics, treatment and managemen...

Aug 2023 38092485
A deep learning method for replicate-based analysis of chromosome conformation contacts using Siamese neural networks.

The organisation of the genome in nuclear space is an important frontier of biology. Chromosome conf...

Aug 2023 37591842
Artificial intelligence in cancer diagnosis and therapy: Current status and future perspective.

Artificial intelligence (AI) in healthcare plays a pivotal role in combating many fatal diseases, su...

Aug 2023 37688994
Predicting congenital renal tract malformation genes using machine learning.

Congenital renal tract malformations (RTMs) are the major cause of severe kidney failure in children...

Aug 2023 37580336
Deep Learning for Detecting BRCA Mutations in High-Grade Ovarian Cancer Based on an Innovative Tumor Segmentation Method From Whole Slide Images.

BRCA1 and BRCA2 genes play a crucial role in repairing DNA double-strand breaks through homologous r...

Aug 2023 37580018
Unlocking the Potential of Zebrafish Research with Artificial Intelligence: Advancements in Tracking, Processing, and Visualization.

Zebrafish have become a widely accepted model organism for biomedical research due to their strong c...

Aug 2023 37558927
GENERA: A Combined Genetic/Deep-Learning Algorithm for Multiobjective Target-Oriented De Novo Design.

This study introduces a new de novo design algorithm called that combines the capabilities of a dee...

Aug 2023 37556857
Post-Processing Fairness Evaluation of Federated Models: An Unsupervised Approach in Healthcare.

Modern Healthcare cyberphysical systems have begun to rely more and more on distributed AI leveragin...

Aug 2023 37097792
Identification of antigen-presentation related B cells as a key player in Crohn's disease using single-cell dissecting, hdWGCNA, and deep learning.

Crohn's disease (CD) arises from intricate intercellular interactions within the intestinal lamina p...

Aug 2023 37550553
Interpretable single-cell transcription factor prediction based on deep learning with attention mechanism.

Predicting the transcription factor binding site (TFBS) in the whole genome range is essential in ex...

Aug 2023 37598467
Machine learning-based ensemble approach in prediction of lung cancer predisposition using XRCC1 gene polymorphism.

The employment of machine learning approaches has shown promising results in predicting cancer. In t...

Aug 2023 37545160
Towards in silico CLIP-seq: predicting protein-RNA interaction via sequence-to-signal learning.

We present RBPNet, a novel deep learning method, which predicts CLIP-seq crosslink count distributio...

Aug 2023 37542318
Development of webcam-collected and artificial-intelligence-derived social and cognitive performance measures for neurodevelopmental genetic syndromes.

This study focused on the development and initial psychometric evaluation of a set of online, webcam...

Aug 2023 37534867
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