Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 4663-4683 of 11,117 articles
A machine learning-based gene signature of response to the novel alkylating agent LP-184 distinguishes its potential tumor indications.

BACKGROUND: Non-targeted cytotoxics with anticancer activity are often developed through preclinical...

Mar 2021 33653269
Machine learning and bioinformatic analysis of brain and blood mRNA profiles in major depressive disorder: A case-control study.

This study analyzed gene expression messenger RNA data, from cases with major depressive disorder (M...

Mar 2021 33645908
2passtools: two-pass alignment using machine-learning-filtered splice junctions increases the accuracy of intron detection in long-read RNA sequencing.

Transcription of eukaryotic genomes involves complex alternative processing of RNAs. Sequencing of f...

Mar 2021 33648554
Investigating the relationship between the SNCA gene and cognitive abilities in idiopathic Parkinson's disease using machine learning.

Cognitive impairments are prevalent in Parkinson's disease (PD), but the underlying mechanisms of th...

Mar 2021 33649398
DNN-m6A: A Cross-Species Method for Identifying RNA N6-Methyladenosine Sites Based on Deep Neural Network with Multi-Information Fusion.

As a prevalent existing post-transcriptional modification of RNA, N6-methyladenosine (m6A) plays a c...

Feb 2021 33670877
Parallel Binary Image Cryptosystem Via Spiking Neural Networks Variants.

Due to the inefficiency of multiple binary images encryption, a parallel binary image encryption fra...

Feb 2021 33637028
On the Juridical Relevance of the Phenomenological Notion of Person in Max Scheler and Edith Stein.

The paper presents a semiotic interpretation of the phenomenological debate on the notion of person,...

Feb 2021 35909456
PFP-WGAN: Protein function prediction by discovering Gene Ontology term correlations with generative adversarial networks.

Understanding the functionality of proteins has emerged as a critical problem in recent years due to...

Feb 2021 33630862
JCS: An Explainable COVID-19 Diagnosis System by Joint Classification and Segmentation.

Recently, the coronavirus disease 2019 (COVID-19) has caused a pandemic disease in over 200 countrie...

Feb 2021 33600316
Predicting dynamic cellular protein-RNA interactions by deep learning using in vivo RNA structures.

Interactions with RNA-binding proteins (RBPs) are integral to RNA function and cellular regulation, ...

Feb 2021 33623109
Identification of RNA pseudouridine sites using deep learning approaches.

Pseudouridine(Ψ) is widely popular among various RNA modifications which have been confirmed to occu...

Feb 2021 33621235
Single Cell RNA-Seq and Machine Learning Reveal Novel Subpopulations in Low-Grade Inflammatory Monocytes With Unique Regulatory Circuits.

Subclinical doses of LPS (SD-LPS) are known to cause low-grade inflammatory activation of monocytes,...

Feb 2021 33708217
Genetics and voice production in childhood and adolescence - a review.

Adolescence is a challenging time of change in voicing, normally and in pathology. An increased focu...

Feb 2021 35663784
Deep6mA: A deep learning framework for exploring similar patterns in DNA N6-methyladenine sites across different species.

N6-methyladenine (6mA) is an important DNA modification form associated with a wide range of biologi...

Feb 2021 33600435
Potential applications of deep learning in single-cell RNA sequencing analysis for cell therapy and regenerative medicine.

When used in cell therapy and regenerative medicine strategies, stem cells have potential to treat m...

Feb 2021 33587792
Fast and precise single-cell data analysis using a hierarchical autoencoder.

A primary challenge in single-cell RNA sequencing (scRNA-seq) studies comes from the massive amount ...

Feb 2021 33589635
HSM6AP: a high-precision predictor for the Homo N6-methyladenosine (m^6 A) based on multiple weights and feature stitching.

Recent studies have shown that RNA methylation modification can affect RNA transcription, metabolism...

Feb 2021 33446014
TranSynergy: Mechanism-driven interpretable deep neural network for the synergistic prediction and pathway deconvolution of drug combinations.

Drug combinations have demonstrated great potential in cancer treatments. They alleviate drug resist...

Feb 2021 33577560
DeepCAPE: A Deep Convolutional Neural Network for the Accurate Prediction of Enhancers.

The establishment of a landscape of enhancers across human cells is crucial to deciphering the mecha...

Feb 2021 33581335
Deep diversification of an AAV capsid protein by machine learning.

Modern experimental technologies can assay large numbers of biological sequences, but engineered pro...

Feb 2021 33574611
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