Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 505-525 of 11,636 articles
Integrative systems biology identifies PSMB2 as a core oxidative stress-associated target in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) represents one of the most aggressive and therapeutically chall...

(2)
Aug 2026 42624926
RNA splicing in health and disease.

RNA splicing expands the functional output of eukaryotic genomes by enabling individual precursor me...

(1)
Aug 2026 42625101
Interpretable distillation reveals that deep learning splicing models suffer from pervasive confounders and blind spots.

BACKGROUND: Predicting RNA splicing from genomic sequence is a crucial task for understanding gene r...

(1)
Aug 2026 42625183
A hypersensitive neuromorphic airflow sensor inspired by vision-compensatory scorpion mechanoreceptors for respiratory pattern analysis.

Efficient acquisition of spatial airflow information is vital for organisms to orient within complex...

(1)
Aug 2026 42623440
Toward foundation-model-assisted biomechanical simulation of the knee joint: Current evidence, limitations, and future directions.

Subject-specific finite element analysis (FEA) can estimate tissue-level stress, strain, contact pre...

(1)
Aug 2026 42623379
Advanced gene editing technologies for oncology mechanisms, applications, and clinical implementation.

Advanced gene editing tools have transformed oncology by facilitating precise molecular therapies ai...

(3)
Aug 2026 42624898
Downstream-Aware Automated QC of Images and AI-Generated Segmentations.

Automated deep learning-based segmentation is increasingly used in medical imaging to enable rapid b...

Aug 2026 42625024
Biallelic loss of RB1 in hepatocellular carcinoma as synthetic lethal target for artificial intelligence-guided therapy.

The retinoblastoma (RB1) gene is a critical tumor suppressor that regulates cell cycle progression a...

(4)
Aug 2026 42618565
NRF2-mediated ferroptosis suppression defines a cancer-specific vulnerability in tumors.

NRF2 is a master regulator of redox and metabolic homeostasis that protects normal tissues from stre...

(1)
Aug 2026 42623935
The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity.

Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent pr...

(1)
Aug 2026 42615388
Integrating machine learning and multi-omics analysis to identify and validate key genes associated with periodontitis.

AIMS: Early detection and intervention are crucial for effective management of periodontitis. Our st...

(2)
Aug 2026 42615493
Piezo1 channel: structure, mechanogating mechanism, functions, diseases and therapeutic strategy.

The Piezo1 channel is a mechanosensitive, non-selective cation channel that converts mechanical forc...

(2)
Aug 2026 42616243
Applications of synthetic biology in biomedicine.

Based on the principles of engineering reconstruction and programmable design, synthetic biology is ...

Aug 2026 42616280
Carboxyl-terminal blockade of sortilin binding enhances progranulin gene therapy in a mouse model of frontotemporal dementia.

Frontotemporal dementia is commonly caused by loss-of-function mutations in the progranulin gene. Po...

Aug 2026 42616842
Precision Medicine in Combating Antimicrobial Resistance: A Comprehensive Review.

Antimicrobial resistance (AMR) represents one of the most pressing threats to global public health, ...

(1)
Aug 2026 42617757
Molecular clustering in osteoarthritis primary tissues identifies shared inflammatory and tissue-specific pathway profiles.

OBJECTIVES: To disentangle the molecular heterogeneity of knee osteoarthritis (OA) through the class...

(1)
Aug 2026 42617791
Prediction of lignocellulosic pretreatment performance using deep eutectic solvents based on IWOA-Stacking.

To enable rapid and accurate prediction of lignocellulosic pretreatment performance using deep eutec...

Aug 2026 42617818
Hematopoietic stem cell aging: a review of transcriptional and multi-omics insights and potential paths for AI integration.

Hematopoietic stem cell (HSC) aging underlies age-related immune decline, anemia and increased risk ...

(10)
Aug 2026 42618695
Disease-specific tau polymorphs are associated with unique protein networks across proteinopathies.

Tau protein aggregates adopt distinct conformations across tauopathies, yet the protein interactions...

Aug 2026 42613429
Characterization of Genetic Risk Factors of Cerebral Small Vessel Disease Based on Large-scale Transcriptome Profiling.

Cerebral small vessel disease (CSVD) is a major contributor to stroke and dementia, and it endangers...

(2)
Aug 2026 42613743
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