Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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MRCNN: a deep learning model for regression of genome-wide DNA methylation.

BACKGROUND: Determination of genome-wide DNA methylation is significant for both basic research and ...

Apr 2019 30967120
DeepHistone: a deep learning approach to predicting histone modifications.

MOTIVATION: Quantitative detection of histone modifications has emerged in the recent years as a maj...

Apr 2019 30967126
Predicting DNA Methylation States with Hybrid Information Based Deep-Learning Model.

DNA methylation plays an important role in the regulation of some biological processes. Up to now, w...

Apr 2019 30951477
Prediction of Long Non-Coding RNAs Based on Deep Learning.

With the rapid development of high-throughput sequencing technology, a large number of transcript se...

Apr 2019 30987229
Analyzing DNA methylation patterns in subjects diagnosed with schizophrenia using machine learning methods.

Schizophrenia is a common mental disorder with high heritability. It is genetically complex and to d...

Apr 2019 31022588
Seq2seq Fingerprint with Byte-Pair Encoding for Predicting Changes in Protein Stability upon Single Point Mutation.

The engineering of stable proteins is crucial for various industrial purposes. Several machine learn...

Apr 2019 30946675
Application of Single-Nucleotide Polymorphisms in the Diagnosis of Autism Spectrum Disorders: A Preliminary Study with Artificial Neural Networks.

Autism spectrum disorder (ASD) includes different neurodevelopmental disorders characterized by defi...

Apr 2019 30937628
Predicting EGFR mutation status in lung adenocarcinoma on computed tomography image using deep learning.

Epidermal growth factor receptor (EGFR) genotyping is critical for treatment guidelines such as the ...

Mar 2019 30635290
An Adolescent with Progressive Enlargement of Digits: Case report and proposed diagnostic criteria for macrodystrophia lipomatosa.

Macrodystrophia lipomatosa (ML) is a rare congenital non-hereditary condition caused by an increase ...

Mar 2019 30988981
Deep Collaborative Filtering for Prediction of Disease Genes.

Accurate prioritization of potential disease genes is a fundamental challenge in biomedical research...

Mar 2019 30932845
Deep-learning augmented RNA-seq analysis of transcript splicing.

A major limitation of RNA sequencing (RNA-seq) analysis of alternative splicing is its reliance on h...

Mar 2019 30923373
LUADpp: an effective prediction model on prognosis of lung adenocarcinomas based on somatic mutational features.

BACKGROUND: Lung adenocarcinoma is the most common type of lung cancers. Whole-genome sequencing stu...

Mar 2019 30902072
Enhancer prediction with histone modification marks using a hybrid neural network model.

Enhancer is a DNA sequence of a genome that controls transcription of downstream target genes. Enhan...

Mar 2019 30905748
Biochemical, machine learning and molecular approaches for the differential diagnosis of Mucopolysaccharidoses.

This study was aimed to construct classification and regression tree (CART) model of glycosaminoglyc...

Mar 2019 30903511
Group Lasso Regularized Deep Learning for Cancer Prognosis from Multi-Omics and Clinical Features.

Accurate prognosis of patients with cancer is important for the stratification of patients, the opti...

Mar 2019 30901858
Molecular Signatures of Fusion Proteins in Cancer.

Although gene fusions are recognized as driver mutations in a wide variety of cancers, the general m...

Mar 2019 32219217
RNA sequencing and swarm intelligence-enhanced classification algorithm development for blood-based disease diagnostics using spliced blood platelet RNA.

Blood-based diagnostics tests, using individual or panels of biomarkers, may revolutionize disease d...

Mar 2019 30894694
Varifocal-Net: A Chromosome Classification Approach Using Deep Convolutional Networks.

Chromosome classification is critical for karyotyping in abnormality diagnosis. To expedite the diag...

Mar 2019 30908259
Gene Expression Classification of Lung Adenocarcinoma into Molecular Subtypes.

As one of the most common malignancies in the world, lung adenocarcinoma (LUAD) is currently difficu...

Mar 2019 30892233
MetaPheno: A critical evaluation of deep learning and machine learning in metagenome-based disease prediction.

The human microbiome plays a number of critical roles, impacting almost every aspect of human health...

Mar 2019 30885720
Incorporating microbial community data with machine learning techniques to predict feed substrates in microbial fuel cells.

The complicated interactions that occur in mixed-species biotechnologies, including biosensors, hind...

Mar 2019 30909014
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