Genetics

Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

11,138 articles

Subcategories: Genetics

Showing 5482-5502 of 11,138 articles

Double-integrated mimic enzymes for the visual screening of Microcystin-LR: Copper hydroxide nanozyme and G-quadruplex/hemin DNAzyme.

Recently, mimic enzymes have obtained particular interest by their high activity, stability, and bio...

Dec 2018 30712583

Insight to Improve α-L-Arabinofuranosidase Productivity in and Its Application on Corn Stover Degradation.

α-L-arabinofuranosidase (ARA) with enhanced specific activity and in large amounts, is needed for a ...

Dec 2018 30631307

Transcription factor binding site clusters identify target genes with similar tissue-wide expression and buffer against mutations.

The distribution and composition of -regulatory modules composed of transcription factor (TF) bindi...

Dec 2018 31001412

Embracing Environmental Genomics and Machine Learning for Routine Biomonitoring.

Genomics is fast becoming a routine tool in medical diagnostics and cutting-edge biotechnologies. Ye...

Dec 2018 30554770

Identifying mouse developmental essential genes using machine learning.

The genes that are required for organismal survival are annotated as 'essential genes'. Identifying ...

Dec 2018 30563825

Knowledge base toward understanding actionable alterations and realizing precision oncology.

In Japan, the National Cancer Center and university hospitals have initiated next-generation sequenc...

Dec 2018 30542800

Leveraging Multilayered "Omics" Data for Atopic Dermatitis: A Road Map to Precision Medicine.

Atopic dermatitis (AD) is a complex multifactorial inflammatory skin disease that affects ~280 milli...

Dec 2018 30631320

Biomarkers and polymorphisms in pancreatic neuroendocrine tumors treated with sunitinib.

Several circulating biomarkers and single nucleotide polymorphisms (SNPs) have been correlated with ...

Dec 2018 30651923

Functional expression of porcine interferon-α using a combinational strategy in Pichia pastoris GS115.

Porcine interferon-α (pIFN-α) could be used as the vaccine adjuvant to enhance the antiviral ability...

Dec 2018 30638508

Identifying disease genes using machine learning and gene functional similarities, assessed through Gene Ontology.

Identifying disease genes from a vast amount of genetic data is one of the most challenging tasks in...

Dec 2018 30532199

Identification of tissue-specific tumor biomarker using different optimization algorithms.

BACKGROUND: Identification of differentially expressed genes, i.e., genes whose transcript abundance...

Dec 2018 30535858

Prediction of CRISPR sgRNA Activity Using a Deep Convolutional Neural Network.

The CRISPR-Cas9 system derived from adaptive immunity in bacteria and archaea has been developed int...

Dec 2018 30485088

Contrast enhancement is a prognostic factor in IDH1/2 mutant, but not in wild-type WHO grade II/III glioma as confirmed by machine learning.

BACKGROUND: Mutation of the isocitrate dehydrogenase (IDH) gene and co-deletion on chromosome 1p/19q...

Dec 2018 30529899

Effect of inter-individual variability in human liver cytochrome P450 isozymes on cyclophosphamide-induced micronucleus formation.

We investigated the relationship between metabolic activities of cytochrome P450 (CYP) isozymes pres...

Dec 2018 30678826

Improving the calling of non-invasive prenatal testing on 13-/18-/21-trisomy by support vector machine discrimination.

With the advance of next-generation sequencing (NGS) technologies, non-invasive prenatal testing (NI...

Dec 2018 30517156

A hybrid approach for automated mutation annotation of the extended human mutation landscape in scientific literature.

As the cost of DNA sequencing continues to fall, an increasing amount of information on human geneti...

Dec 2018 30815103

Setting Up a Surface-Enhanced Raman Scattering Database for Artificial-Intelligence-Based Label-Free Discrimination of Tumor Suppressor Genes.

The quality of input data in deep learning is tightly associated with the ultimate performance of th...

Dec 2018 30456938

Porcine single nucleotide polymorphisms and their functional effect: an update.

OBJECTIVE: To aid in the development of a comprehensive list of functional variants in the swine gen...

Dec 2018 30514360

iSEE: Interface structure, evolution, and energy-based machine learning predictor of binding affinity changes upon mutations.

Quantitative evaluation of binding affinity changes upon mutations is crucial for protein engineerin...

Dec 2018 30417935

MSIpred: a python package for tumor microsatellite instability classification from tumor mutation annotation data using a support vector machine.

Microsatellite instability (MSI) is characterized by high degree of polymorphism in microsatellite l...

Dec 2018 30510242

Genotoxicity evaluation of titanium dioxide nanoparticles using the mouse lymphoma assay and the Ames test.

Titanium dioxide nanoparticles (TiO-NPs) are widely used in the cosmetics, health, and food industri...

Dec 2018 30678824

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