Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 673-693 of 11,038 articles
Testosterone-Sparing Treatment Strategies for Biochemically Recurrent Prostate Cancer After Radical Prostatectomy.

PURPOSE OF REVIEW: Biochemical recurrence (BCR) after radical prostatectomy occurs in up to one-thir...

Mar 2026 41915319
Seeing and Feeling DNA Methylation: Single-Molecule Biophysics Meets Machine Learning.

DNA methylation at 5-methylcytosine (5mC) is crucial for embryonic development and cellular function...

Mar 2026 41916906
Perspectives from machine learning and multi-omics to decoding the effects of VDAC2 malignant subsets on tumor evolution.

VDAC2's known role in cancer and immune regulation via enhancing the CD8+ T cell-mediated killing, a...

Mar 2026 41917254
Rapid and noninvasive artificial intelligence-assisted diagnostic method for oral squamous cell carcinoma.

Oral squamous cell carcinoma (OSCC) remains the most common head and neck malignancy, for which earl...

Mar 2026 41917329
Single-Cell Sequencing and Transcriptomic Sequencing Exploration of the Mechanisms Governing Lactylation in Mitochondrial Diseases.

Mitochondrial diseases (MDs) consist of a heterogeneous spectrum of disorders resulting from mutatio...

Mar 2026 41801247
Multi-Omics Analysis for Identifying Glial Dysfunction-Associated Genes as Therapeutic Targets and Drug Candidates in Alzheimer's Disease.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decl...

Mar 2026 41863516
Artificial Intelligence in Phenylketonuria: Bridging Conventional Gaps in Diagnosis and Treatment- A Systematic Review.

INTRODUCTION: Phenylketonuria (PKU) is an autosomal recessive condition of phenylalanine metabolism,...

Mar 2026 41915577
Revisiting the NETs-CYBB-p38 MAPK axis in bronchiectasis: The underlying oxidative injury mechanism.

BACKGROUND: Bronchiectasis is a chronic neutrophilic respiratory disease frequently complicated by P...

Mar 2026 41916025
AI-Guided 4D Printing of Carnivorous Plants-Inspired Microneedles for Accelerated Wound Healing.

Artificial intelligence (AI) integrated with bioinspired design enables the development of materials...

Mar 2026 41910374
Characterising oral microbial signatures for periodontal disease in the NHANES population.

OBJECTIVE: This study aims to characterise the relationship between the oral microbiota and periodon...

Mar 2026 41910434
Polygenic and polysocial risk scores in post-type 2 diabetes dementia: Risk stratification and predictive modeling in the UK Biobank cohort.

BackgroundDementia is a common complication of type 2 diabetes mellitus (T2DM), influenced by both g...

Mar 2026 41910452
Neoantigen Targeting as a Novel Approach for Therapy-Resistant Tumors.

Neoantigens have emerged as central targets in the development of individualized cancer vaccines, as...

Mar 2026 41912995
Identification of rheumatoid arthritis manganese metabolism-related diagnostic biomarkers through bulk and single-cell RNA sequencing analysis.

BACKGROUND: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized primarily by sy...

Mar 2026 41913032
Rewiring the cardiovascular epigenome: the multi-target strategy of traditional Chinese medicine.

Epigenetic mechanisms, including DNA methylation, histone modifications, and non-coding RNAs (ncRNAs...

Mar 2026 41906543
IGSF9 drives malignant transformation and predicts early-stage lung adenocarcinoma in integrated transcriptomic analyses.

PURPOSE: Lung adenocarcinoma (LUAD), the most common subtype of non-small cell lung cancer (NSCLC), ...

Mar 2026 41904745
Bridging the Scales via Personalized Cellular Modeling and Deep Phenotyping in Schizophrenia.

IMPORTANCE: While growing evidence implicates synaptic dysfunction as a key pathophysiological mecha...

Mar 2026 41902754
WGCNA and machine learning identify mitochondria programmed cell death-related genes as diagnostic biomarkers for septic shock.

Septic shock (SS), the most severe stage of sepsis, has a high mortality rate. Mitochondria-mediated...

Mar 2026 41902830
PTBP1 knockdown reprograms glioma stem cells into neuronal-like cells and suppresses tumorigenesis via the DUSP5-ERK1/2 signaling pathway.

BACKGROUND: Glioblastoma (GBM), the most prevalent and aggressive primary brain tumor in adults, has...

Mar 2026 41903206
Machine learning-predicted chromatin organization landscape across pediatric tumors.

Structural variants (SVs) are increasingly recognized as important contributors to oncogenesis throu...

Mar 2026 41904260
Investigating Phase Separation in Genome Folding via Multiscale Computational Modeling.

The 3D organization of the genome is central to gene regulation, and phase separation has emerged as...

Mar 2026 41902470
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