Hematology

Latest AI and machine learning research in hematology for healthcare professionals.

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A neural network based model effectively predicts enhancers from clinical ATAC-seq samples.

Enhancers are cis-acting sequences that regulate transcription rates of their target genes in a cell-specific manner and harbor disease-associated sequence variants in cognate cell types. Many complex diseases are associated with enhancer malfunction, necessitating the discovery and study of enhancers from clinical samples. Assay for Transposase Accessible Chromatin (ATAC-seq) technology can inter...

Oct 30 2018 30375457

Cooling and Cryopreservation of Equine Platelet-Rich Plasma With Dimethyl Sulfoxide and Trehalose.

Equine platelet-rich plasma (PRP) has been used in horses to repair bone, articular and tendinous lesions, laminitis, and even endometritis. However, platelets have a very limited lifespan, which makes it difficult to prepare and use PRP, except in loco. With the aim to produce PRP with higher platelet viability for clinical purposes, the effects of the cryoprotectants dimethyl sulfoxide (DMSO) an...

Oct 27 2018 30929774
Photoplethysmography and Deep Learning: Enhancing Hypertension Risk Stratification.

Blood pressure is a basic physiological parameter in the cardiovascular circulatory system. Long-term abnormal blood pressure will lead to various car...

Oct 26 2018 30373211
Blood Pressure Assessment with Differential Pulse Transit Time and Deep Learning: A Proof of Concept.

BACKGROUND: Modern clinical environments are laden with technology devices continuously gathering physiological data from patients. This is especially...

Oct 25 2018 30815461
Classification of acute lymphoblastic leukemia using deep learning.

Acute Leukemia is a life-threatening disease common both in children and adults that can lead to death if left untreated. Acute Lymphoblastic Leukemia...

Oct 23 2018 30351463
Ensemble of machine learning algorithms using the stacked generalization approach to estimate the warfarin dose.

Warfarin dosing remains challenging due to narrow therapeutic index and highly individual variability. Incorrect warfarin dosing is associated with de...

Oct 19 2018 30339708
A Magnetically Controlled Soft Microrobot Steering a Guidewire in a Three-Dimensional Phantom Vascular Network.

Magnetically actuated soft robots may improve the treatment of disseminated intravascular coagulation. Significant progress has been made in the devel...

Oct 12 2018 30312145
Analysis of platelet-activating factors in severe sepsis by flow cytometry and its correlation with clinical sepsis scoring system: A pilot study.

BACKGROUND: Sepsis is a major global healthcare concern. Platelets and leucocytes play a key role in sepsis. Whole blood flow cytometry (FCM) is a pow...

Oct 10 2018 31719738
Comparison of 2 Natural Language Processing Methods for Identification of Bleeding Among Critically Ill Patients.

IMPORTANCE: To improve patient safety, health care systems need reliable methods to detect adverse events in large patient populations. Events are oft...

Oct 5 2018 30646240
Machine learning reveals chronic graft--host disease phenotypes and stratifies survival after stem cell transplant for hematologic malignancies.

The application of machine learning in medicine has been productive in multiple fields, but has not previously been applied to analyze the complexity ...

Sep 20 2018 30237265
Classification of Overt and Covert Speech for Near-Infrared Spectroscopy-Based Brain Computer Interface.

People suffering from neuromuscular disorders such as locked-in syndrome (LIS) are left in a paralyzed state with preserved awareness and cognition. I...

Sep 7 2018 30205476
Mixed effect machine learning: A framework for predicting longitudinal change in hemoglobin A1c.

Accurate and reliable prediction of clinical progression over time has the potential to improve the outcomes of chronic disease. The classical approac...

Sep 4 2018 30189255
Development and Validation of a Deep Learning System for Staging Liver Fibrosis by Using Contrast Agent-enhanced CT Images in the Liver.

Purpose To develop and validate a deep learning system (DLS) for staging liver fibrosis by using CT images in the liver. Materials and Methods DLS for...

Sep 4 2018 30179104
Exploring the phenolic profile, antioxidant, antidiabetic and anti-hemolytic potential of Prunus avium vegetal parts.

The aim of the present work was to evaluate the phenolic profile of leaves, stems and flowers of P. avium and their biological potential. For this pur...

Sep 2 2018 30716986
Can Deep Learning Improve Genomic Prediction of Complex Human Traits?

The genetic analysis of complex traits does not escape the current excitement around artificial intelligence, including a renewed interest in "deep le...

Aug 31 2018 30171033
The utility of artificial neural networks and classification and regression trees for the prediction of endometrial cancer in postmenopausal women.

OBJECTIVE: Artificial neural networks (ANNs) and classification and regression trees (CARTs) have been previously used for the prediction of cancer in...

Aug 24 2018 30149185
An Intelligent Model for Blood Vessel Segmentation in Diagnosing DR Using CNN.

Diabetic retinopathy (DR) is an eye disease, which affects the people who are all having the diabetes for more than 10 years. The ophthalmologist iden...

Aug 15 2018 30109508
Increased vitamin B levels in children with zinc deficiency.

Additional nutritional deficiencies may accompany zinc deficiency. We determined the vitamin B levels in patients with zinc (Zn) deficiency. This retr...

Aug 10 2018 30095365
Cell-Like Micromotors.

In the past decade, versatile micro- and nanosized machines have emerged as active agents for large-scale detoxification, sensing, microfabrication, a...

Aug 3 2018 30074758
Postoperative bleeding risk prediction for patients undergoing colorectal surgery.

BACKGROUND: There is limited consensus regarding risk factors for postoperative bleeding. The objective of this work was to investigate the capability...

Jul 20 2018 30033185
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