Latest AI and machine learning research in hemophilia for healthcare professionals.
Hemophilia A (HA) is caused by factor VIII (FVIII) deficiency and requires lifelong prophylaxis. Alt...
Antibiotic prophylaxis decision-making in endodontics represents a core competency in dental educati...
INTRODUCTION: Pharmacoeconomic principles are increasingly shaping modern obstetric pharmacology as ...
Over four decades, translational hepatology has evolved from empirical observations into an evidence...
INTRODUCTION: Advances in hemophilia treatment have improved life expectancy, yet challenges remain ...
Drug‑tolerant persister cells represent a major barrier to durable responses in cases of epidermal g...
BACKGROUND: Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy, but can cause se...
This study aims to design and evaluate novel therapeutic binders targeting the ATP-binding region of...
Accurate identification of repurposable BCL-2 ligands requires not only plausible bound complex stru...
Multidrug resistance (MDR) mediated by ATP-binding cassette transporter G2 (ABCG2) remains a major c...
Histone deacetylase 8 (HDAC8) is an emerging epigenetic target implicated in cancer, neurodegenerati...
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder worldwide, affectin...
MAPKAPK2 is a promising therapeutic target in numerous diseases. However, many MAPKAPK2 inhibitors a...
New Delhi metallo-β-lactamase-1 (NDM-1), which has emerged globally, exhibits resistance to almost a...
Topoisomerase I (TOP1) is a crucial anticancer target, but the development of traditional TOP1 inhib...
Parkinson's disease (PD) is a complex neurodegenerative disorder in which environmental toxins play ...
INTRODUCTION: Personalization of Janus kinase inhibitor (JAKi) therapy in rheumatoid arthritis (RA) ...
Rheumatoid arthritis (RA) progression is driven by the pathogenic transformation of stromal fibrobla...
The liver is characterized by abundant blood supply and intricate anatomical architecture,rendering ...
Plasmodium falciparum Calcium-Dependent Protein Kinase 4 (PfCDPK4) is a validated target for malaria...
BACKGROUND: Hepatocellular carcinoma (HCC) is characterized by marked heterogeneity and an immunosup...