Hematology

Hemophilia

Latest AI and machine learning research in hemophilia for healthcare professionals.

4,162 articles
Stay Ahead - Weekly Hemophilia research updates
Subscribe
Browse Categories
Showing 463-483 of 4,162 articles
Identification of compounds that repress DUX4 expression in facioscapulohumeral muscular dystrophy

Facioscapulohumeral muscular dystrophy (FSHD) is caused by epigenetic dysregulation of the disease l...

Explainable AI for end-to-end pathogen target discovery and molecular design

Drug discovery is often constrained by target identification, a bottleneck especially acute in antim...

Multimodal Machine Learning Reveals the Genomic and Proteomic Architecture of Heart Failure with Preserved Ejection Fraction

Heart failure with preserved ejection fraction (HFpEF) affects over 30 million people and lacks dise...

Results of a large scale study of the binding of 50 type IIinhibitors to 348 kinases: The role of protein reorganization

Kinase family proteins constitute the second largest protein class targeted in drug development effo...

BEACON: predicting side effects and therapeutics outcomes to drugs by Bridging knowlEdge grAph with CONtextual language model

Biomedical knowledge graphs encode millions of relationships between drugs, proteins, pathways, and ...

Deep Learning-Guided Discovery of Celestolide as a Natural Allosteric Inhibitor Targeting CYP51 and Its Application in Strawberry Preservation.

Most CYP51 inhibitors act competitively and are prone to resistance, whereas allosteric inhibitors h...

Jul 2025 40576401
Use of machine learning techniques to predict poor survival after hematopoietic cell transplantation for myelofibrosis.

With the incorporation of effective therapies for myelofibrosis (MF), accurately predicting outcomes...

Jun 2025 40145857
[Progress in neoadjuvant immunotherapy for locally advanced rectal cancer].

Neoadjuvant chemoradiotherapy (NACRT) is the standard treatment for locally advanced rectal cancer (...

Jun 2025 40550665
Structure-based artificial intelligence-aided design of MYC-targeting degradation drugs for cancer therapy.

The MYC protein is an oncoprotein that plays a crucial role in various cancers. Although its signifi...

Jun 2025 40288261
Active Learning-Guided Hit Optimization for the Leucine-Rich Repeat Kinase 2 WDR Domain Based on In Silico Ligand-Binding Affinities.

The leucine-rich repeat kinase 2 (LRRK2) is the most mutated gene in familial Parkinson's disease, a...

Jun 2025 40415386
Identification of therapeutics against PfPK6 protein of Plasmodium falciparum: Structure and Deep Learning approach.

The Plasmodium falciparum Protein Kinase 6 (PfPK6) is a serine/threonine protein kinase categorized ...

Jun 2025 40288672
Dumpling GNN: Hybrid GNN Enables Better ADC Payload Activity Prediction Based on the Chemical Structure.

Antibody-drug conjugates (ADCs) are promising cancer therapeutics, but optimizing their cytotoxic pa...

May 2025 40430004
Protein Profiles Predict Treatment Responses to the PI3K Inhibitor Umbralisib in Patients with Chronic Lymphocytic Leukemia.

PURPOSE: The management of chronic lymphocytic leukemia (CLL) has significantly improved with target...

May 2025 40085050
Transforming Healthcare: The Role of Artificial Intelligence.

The integration of artificial intelligence (AI) into healthcare is revolutionising the industry by e...

May 2025 40380728
Single-cell mitochondrial morphomics reveals cellular heterogeneity and predicts complex I, III, and ATP synthase Inhibition responses.

Mitochondrial heterogeneity drives diverse cellular responses in neurodegenerative diseases, complic...

May 2025 40369116
A deep learning and molecular modeling approach to repurposing Cangrelor as a potential inhibitor of Nipah virus.

Deforestation, urbanization, and climate change have significantly increased the risk of zoonotic di...

May 2025 40355437
Browse Categories