Cardiovascular

Hypertension

Latest AI and machine learning research in hypertension for healthcare professionals.

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Phenotypic Selectivity of Artificial Intelligence-enhanced Electrocardiography in Cardiovascular Diagnosis and Risk Prediction

Artificial intelligence (AI)-enhanced electrocardiogram (ECG) models are designed to detect specific anatomical and functional cardiac abnormalities. Understanding the selectivity of their phenotypic associations is essential to inform their clinical use. Here, we sought to assess whether AI-ECG models function as condition-specific classifiers or broader cardiovascular risk markers. We included f...

Metabolic Subphenotypes of Obstructive Sleep Apnea: NHANES 2017-2020 (pre-pandemic)

OSA and MetS have a bidirectional relationship but increasing evidence suggests metabolic heterogeneity in OSA, systematic phenotyping of metabolic drivers in OSA are lack. To identify metabolic subphenotypes of OSA and elucidate potential pathophysiological mechanisms using population-level data. To analyze the data related to OSA and MetS from 2,260 participants in the NHANES database (2017–2020...

Contrastive Multi-modal Training with Electrocardiography and Natural Language Echocardiography Reports for Zero-shot Prediction of Structural Heart Disease

Machine learning models for predicting structural heart disease (SHD) from electrocardiography (ECG) traditionally required structured echocardiograph...

Does explainable AI-ECG heart age differentiate pathological from physiological LV remodeling? A multi-cohort analysis including young elite athletes

Artificial intelligence applied to electrocardiography (AI-ECG) can derive a heart age or ECG-age, potentially reflecting waveform patterns that indic...

Deep learning-based prediction of cardiopulmonary disease in retinal images of premature infants

Bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH) are leading causes of morbidity and mortality in premature infants. To determine whet...

ECG-Derived Synthetic Tissue Doppler Waveforms Differentiate Physiological Adaptations in Healthy Athletes from Pathological Patterns Associated with Mortality in Young Individuals

Sudden cardiac death (SCD) in young individuals—especially athletes—remains difficult to diagnose due to overlapping physiological and pathological el...

Development of a Hypertension Risk Prediction Model using Nationally Representative Survey Data: A Machine Learning Approach and Web Application Deployment

Hypertension is a major modifiable risk factor for cardiovascular diseases. Early identification of high-risk individuals using predictive models can ...

Plasma Proteomics Linking Primary and Secondary diseases: Insights into Molecular Mediation from UK Biobank Data

Diabetes, hypertension, and dyslipidemia are major risk factors for cardiovascular (CVD), cerebral, and renal diseases (RD). However, the underlying m...

Comprehensive, Transparent, and Fair Machine Learning Models for Hypertension Risk Prediction: Benchmarking With Framingham, External Validation, Individual-Level Analysis, and Equitable Clinical Utility

Hypertension (HTN) is a leading, yet often underdiagnosed, cause of cardiovascular diseases worldwide. While clinical risk scores like the Framingham ...

Clustered Phenotypes of Hypertensive Heart Disease With Strain Measurements Reveals Distinct Characteristics, Clinical Course, and Prognosis

Hypertensive heart disease (HHD) encompasses diverse clinical profiles, comorbidities, and cardiac remodeling, but current classifications insufficien...

A Self-Explainable Dynamic Risk Monitoring Framework for Predicting Alzheimer’s Disease and Related Dementias

Alzheimer’s Disease and Related Dementias (ADRD) affect millions worldwide and can begin over a decade before symptoms appear. ADRD are generally irre...

Forecasting left ventricular systolic dysfunction in heart failure with artificial intelligence

Objective assessment of left ventricular function remains a key prognosticator that is used to guide therapeutic decisions for patients with heart fai...

TARGET-AI: a foundational approach for the targeted deployment of artificial intelligence electrocardiography in the electronic health record

Artificial intelligence (AI) applied to routine electrocardiograms (ECGs) offers promise for screening of structural heart disease (SHD), yet broad cl...

Harnessing Transformer Models for Cardiovascular Disease Prediction: A Comparison with Conventional Methods

Cardiovascular Diseases (CVDs) remain the leading cause of death worldwide, creating an urgent need for accurate risk prediction. Machine learning (ML...

Combination AI-Machine Learning to Diagnose Pulmonary Hypertension: A Real-World Evidence Cohort Study

Pulmonary hypertension (PH) is a highly morbid disease, but underdiagnosis is common outside of expert referral centers. Consequentially, there may be...

An Explainable Advanced Electrocardiography Score for Diastolic Dysfunction - Derivation, Validation and Prognostic Performance

Diastolic dysfunction is a precursor to heart failure with preserved ejection fraction (HFpEF), and early detection by electrocardiography (ECG) would...

Machine Learning Risk Prediction for Prolonged Hospitalization in Frail Older Adults with Multimorbidity

Frailty and multimorbidity are common in older adults and contribute substantially to prolonged hospitalizations, readmissions, and mortality. Yet, ex...

Cardiac Measurement Calculation on Point-of-Care Ultrasonography with Artificial Intelligence

Point-of-care ultrasonography (POCUS) enables clinicians to obtain critical diagnostic information at the bedside especially in resource limited setti...

Optimized Machine Learning Algorithms for the Classification and Diagnosis of Sleep Disorders

Sleep disorders, including insomnia and obstructive sleep apnea, affect millions of individuals worldwide but are frequently undetected due to the hig...

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