Infectious Disease

Antibacterial and Antibiofilm Activities of Colistin and Ceftazidime-Avibactam Conjugated Silver Nanoparticles.

Multidrug-resistant (MDR) Gram-negative bacteria constitute a major global health concern, and the increasing resistance to last-line antimicrobial agents compels the urgent improvement of novel treatment strategies. The present study aims to produce colistin and ceftazidime-avibactam conjugated silver nanoparticles by eco-friendly synthesis method and to evaluate the antimicrobial and antibiofilm...

AgNPs@Tea Polyphenol-Poly(acrylic acid) Hydrogel Dressing with Synergistic Antibacterial Action and Low Cytotoxicity.

Bacterial infections pose a severe threat to human health, and excessive antibiotic use induces bacterial resistance. Although silver-containing nanoparticles exhibit excellent antimicrobial activity without inducing bacterial resistance, their significant cytotoxicity toward mammalian cells remains problematic. This study developed a AgNPs@tea polyphenol-poly(acrylic acid) (AgNPs@TPP-PAA) hydroge...

Defining the biomarkers in anti-MRSA fractions of soil Streptomycetes by multivariate analysis.

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most alarming antibiotic-resistant pathogens causing nosocomial and community-acquire...

Variations of the chemical components and biological activities of Thymus capitatus essential oil from three regions in Palestine.

Thymus capitatus is a widely utilized medicinal plant in Palestine. The main goal of this study was to assess the phytochemical content of T. capitatu...

Detection of ESBL-producing complex with VITEK 2 system and screening cutoffs for implementing confirmatory tests.

complex (C) are important nosocomial pathogens that can be reservoirs of transmissible extended-spectrum β-lactamase (ESBL) genes. Therefore, it is e...

Serratia marcescens G4 as a novel biocontrol strain against Sclerotinia sclerotiorum infection in soybean.

BACKGROUND: Sclerotinia is a soil-borne disease of soybean caused by Sclerotinia sclerotiorum, which seriously endangers the yield and quality of soyb...

Use of saline-soaked bacterial culture swabs increases bacterial recovery in dogs with superficial bacterial folliculitis.

BACKGROUND: Canine superficial bacterial folliculitis (SBF) is a common recurrent condition with a growing requirement for culture and susceptibility ...

Anti-HBs persistence and anamnestic response among medical interns vaccinated in infancy.

Medical interns are at high risk of acquiring Hepatitis B Virus (HBV) infection during their training. HBV vaccination is the most effective measure t...

HIV-1 suppression and rare dolutegravir resistance in antiretroviral-experienced people with HIV in Liberia.

BACKGROUND: Increasingly, persons with HIV in Liberia are receiving antiretroviral therapy containing the integrase strand-transfer inhibitor (InSTI) ...

In vitro antimicrobial and anticancer potentials of green synthesized luminescent carbon quantum dots derived from artichoke leaves.

Naturally derived carbon quantum dots (CQDs) are novel carbon-based nanomaterials with excellent traits. It is highly demanded to develop CQDs from bi...

Simultaneous quantitative detection of viable Salmonella spp., Shiga toxin-producing Escherichia coli, Bacillus cereus, and Listeria monocytogenes in milk through multiplex real-time PCR.

In our study, a multiplex real-time polymerase chain reaction (mRT-PCR)-based method was established to detect viable Salmonella spp. (SS), Shiga toxi...

Temporal wheat proteome remodeling by deoxynivalenol reveals novel detoxification signatures and strategies across cultivars.

Fusarium head blight (FHB) is a globally devastating fungal disease resulting in reduced grain yield and quality, along with contamination of grains w...

Impact of type 2 diabetes mellitus on apical periodontitis size, endotoxin levels and bacterial load in root canals with necrotic pulp.

INTRODUCTION: This clinical study was conducted to describe the endodontic microbiological profile of teeth with apical periodontitis in patients with...

Investigating endophytic fungi of Calotropis procera for novel bioactive compounds: molecular docking and bioactivity insights.

BACKGROUND: The rising danger of antibiotic resistance and the increasing burden of cancer worldwide have highlighted the necessity for a constant sup...

Bioactivity and chemical screening of endophytic fungi associated with seaweeds Gracilaria sp. and Sargassum sp. of the Bay of Bengal, Bangladesh.

This study explored the great potential of endophytic fungi associated with red seaweed Gracilaria sp. and brown seaweed Sargassum sp. of the Bay of B...

Comparative study on antibacterial activities and removal of iron ions from water using novel modified sand with silver through the hydrothermal technique.

The hydrothermal-calcination technique was used to modify raw sand with silver (Ag) at different weight percentages: 2%, 5%, and 10% using silver nitr...

Isolation and characterization of a bioactive compound from Sphingomonas sanguinis DM with cytotoxic and molecular docking analysis.

Datura metel, a common plant in the Solanaceae family, is known for its valuable medicinal properties. The metabolites created by its rhizosphere bact...

Facile phyto-mediated synthesis of ternary CuO/MnO/ZnO nanocomposite using Nigella Sativa seeds extract: characterization,antimicrobial, and biomedical evaluations.

The phyto-synthesis of ternary CuO/ MnO/ZnO nanocomposite was achieved by the utilization of an eco-friendly, straightforward approach that involved t...

Evaluation of endometrial vascular flow index and echogenicity following experimental induction of subclinical endometritis in dairy cows.

This study was conducted aiming to investigate impacts of experimentally induced endometritis on the vascular perfusion and echogenicity of the endome...

Communication about COVID-19 with urban American Indian and Alaska Native peoples: the role of health literacy, trust, and information source.

BACKGROUND: Developing optimal health communication strategies about COVID-19 and vaccines requires an understanding of the health literacy level of p...