Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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BPAGS: a web application for bacteriocin prediction via feature evaluation using alternating decision tree, genetic algorithm, and linear support vector classifier.

The use of bacteriocins has emerged as a propitious strategy in the development of new drugs to combat antibiotic resistance, given their ability to kill bacteria with both broad and narrow natural spectra. Hence, a compelling requirement arises for a precise and efficient computational model that can accurately predict novel bacteriocins. Machine learning's ability to learn patterns and features ...

Jan 10 2024 38268970

Pharmacokinetics of recombinant human annexin A5 (SY-005) in patients with severe COVID-19.

Annexin A5 is a phosphatidylserine binding protein with anti-inflammatory, anticoagulant and anti-apoptotic properties. Preclinical studies have shown that annexin A5 inhibits pro-inflammatory responses and improves organ function and survival in rodent models of sepsis. This clinical trial aimed to evaluate the pharmacokinetic (PK) properties of the recombinant human annexin A5 (SY-005) in sever...

Jan 10 2024 38269269
Antibiofilm peptides enhance the corrosion resistance of titanium in the presence of .

Titanium alloys have gained popularity in implant dentistry for the restoration of missing teeth and related hard tissues because of their biocompatib...

Jan 10 2024 38274010
CanVaxKB: a web-based cancer vaccine knowledgebase.

Cancer vaccines have been increasingly studied and developed to prevent or treat various types of cancers. To systematically survey and analyze differ...

Jan 9 2024 38204924
Combining Digital and Molecular Approaches Using Health and Alternate Data Sources in a Next-Generation Surveillance System for Anticipating Outbreaks of Pandemic Potential.

Globally, millions of lives are impacted every year by infectious diseases outbreaks. Comprehensive and innovative surveillance strategies aiming at e...

Jan 9 2024 38194263
From Data to Decisions: How Artificial Intelligence Is Revolutionizing Clinical Prediction Models in Plastic Surgery.

The impact of clinical prediction models within artificial intelligence (AI) and machine learning is significant. With its ability to analyze vast amo...

Jan 8 2024 38194624
Awareness and level of digital literacy among students receiving health-based education.

BACKGROUND: Being digitally literate allows health-based science students to access reliable, up-to-date information efficiently and expands the capac...

Jan 8 2024 38191385
Ethnomedicinal uses, phytochemistry, and pharmacology of the genus : a review.

Although medicinal plants have been used by ethnic communities since ancient times to prevent and treat various diseases, only a few have been scienti...

Jan 8 2024 38259280
A facile approach to preparing personalized cancer vaccines using iron-based metal organic framework.

BACKGROUND: Considering the diversity of tumors, it is of great significance to develop a simple, effective, and low-cost method to prepare personaliz...

Jan 8 2024 38259474
Application of hybrid fuzzy interval-based machine learning models on financial time series - A case study of Taiwan biotech index during the epidemic period.

In recent years, the use of machine learning to predict stock market indices has emerged as a vital concern in the FinTech domain. However, the inhere...

Jan 8 2024 38259825
Impacts of ainuovirine-based and efavirenz-based antiretroviral therapies on the lipid profile of HIV/AIDS patients in southern China: a real-world study.

BACKGROUND: The newly approved third-generation oral anti-HIV-1 drug, ainuovirine (ANV), was used in combination with nucleoside reverse transcriptase...

Jan 8 2024 38259850
antibacterial activity of antiretroviral drugs on key commensal bacteria from the human microbiota.

INTRODUCTION: Antiretroviral therapy has improved life expectancy in HIV-infected patients. However, people living with HIV under antiretroviral thera...

Jan 8 2024 38259963
The critical role of neutrophil-endothelial cell interactions in sepsis: new synergistic approaches employing organ-on-chip, omics, immune cell phenotyping and modeling to identify new therapeutics.

Sepsis is a global health concern accounting for more than 1 in 5 deaths worldwide. Sepsis is now defined as life-threatening organ dysfunction caused...

Jan 8 2024 38259971
Simultaneous detection of human norovirus GI, GII and SARS-CoV-2 by a quantitative one-step triplex RT-qPCR.

BACKGROUND: There are many similarities in the clinical manifestations of human norovirus and SARS-CoV-2 infections, and nucleic acid detection is the...

Jan 8 2024 38260899
Anti-ultraviolet, antibacterial, and biofilm eradication activities against of melanins and melanin derivatives from and .

and produced significant amounts of water-insoluble melanins, and our previous study successfully enhanced their water solubility by arginine modifi...

Jan 8 2024 38260905
Attitudes Toward the Adoption of Remote Patient Monitoring and Artificial Intelligence in Parkinson's Disease Management: Perspectives of Patients and Neurologists.

OBJECTIVE: Early detection of Parkinson's Disease (PD) progression remains a challenge. As remote patient monitoring solutions (RMS) and artificial in...

Jan 5 2024 38182935
General Characteristics and Design Taxonomy of Chatbots for COVID-19: Systematic Review.

BACKGROUND: A conversational agent powered by artificial intelligence, commonly known as a chatbot, is one of the most recent innovations used to prov...

Jan 5 2024 38064638
Deep learning-based synthetic dose-weighted LET map generation for intensity modulated proton therapy.

The advantage of proton therapy as compared to photon therapy stems from the Bragg peak effect, which allows protons to deposit most of their energy d...

Jan 5 2024 38091613
The Laboratory Diagnosis of Malaria: A Focus on the Diagnostic Assays in Non-Endemic Areas.

Even if malaria is rare in Europe, it is a medical emergency and programs for its control should ensure both an early diagnosis and a prompt treatment...

Jan 5 2024 38255768
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