Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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An inactivated influenza D virus vaccine partially protects cattle from respiratory disease caused by homologous challenge.

Originally isolated from swine, the proposed influenza D virus has since been shown to be common in cattle. Inoculation of IDV to naïve calves resulted in mild respiratory disease histologically characterized by tracheitis. As several studies have associated the presence of IDV with acute bovine respiratory disease (BRD), we sought to investigate the efficacy of an inactivated IDV vaccine. Vaccina...

Dec 21 2016 28110784

CD4 T Helper Cells Instruct Lymphopenia-Induced Memory-Like CD8 T Cells for Control of Acute LCMV Infection.

Lymphopenic conditions lead to expansion of memory-like T cells (T), which develop from naïve T cells by spontaneous proliferation. T cells are often increased in the elderly population, AIDS patients, and patients recovering from radio- or chemotherapy. At present, it is unclear whether T cells can efficiently respond to foreign antigen and participate in antiviral immunity. To address this quest...

Dec 21 2016 28066432
A genotypic method for determining HIV-2 coreceptor usage enables epidemiological studies and clinical decision support.

BACKGROUND: CCR5-coreceptor antagonists can be used for treating HIV-2 infected individuals. Before initiating treatment with coreceptor antagonists, ...

Dec 20 2016 27998283
A New Synthetic Peptide Having Two Target of Antibacterial Action in ML35.

The increased resistance of microorganisms to the different antimicrobials available to today has highlighted the need to find new therapeutic agents,...

Dec 20 2016 28066341
Characterization and Antibacterial Potential of Lactic Acid Bacterium 4I1 Isolated from Freshwater Fish .

This study was undertaken to characterize a lactic acid bacterium 4I1, isolated from the freshwater fish, . Morphological, biochemical, and molecular ...

Dec 20 2016 28066360
Development of a Zika Virus Infection Model in Cynomolgus Macaques.

Limited availability of Indian rhesus macaques (IRM) is a bottleneck to study Zika virus (ZIKV) pathogenesis and evaluation of appropriate control mea...

Dec 19 2016 28066354
Stimulation of PBMC and Monocyte-Derived Macrophages Toll-Like Receptor Activates Innate Immune Pathways in HIV-Infected Patients on Virally Suppressive Combination Antiretroviral Therapy.

In HIV-infected, combination antiretroviral therapy (cART)-treated patients, immune activation and microbial translocation persist and associate with ...

Dec 19 2016 28066424
Antifungal activity of sterols and dipsacus saponins isolated from Dipsacus asper roots against phytopathogenic fungi.

The in vivo antifungal activity of crude extracts of Dipsacus asper roots was evaluated against the phytopathogenic fungi Botrytis cinerea, Colletotri...

Dec 18 2016 28911735
The Essential Oils of Hairy Roots and Roots of Soil-Grown Plants: Chemical Composition and Antimicrobial, Anti-Inflammatory, and Antioxidant Activities.

The essential oils were isolated by hydrodistillation from the hairy roots (HR) and roots of soil-grown plants (SGR) of and were analyzed by GC-MS me...

Dec 18 2016 28074117
Prospective Study to Assess Progression of Renal Markers after Interruption of Tenofovir due to Nephrotoxicity.

. Prospective studies about the reversibility of tenofovir disoproxil fumarate- (TDF-) related renal impairment remain scarce. . This is an observatio...

Dec 18 2016 28078289
Susceptibility Profiles of Isolates to Streptomycin and Rifampicin in Two Districts of the Eastern Region of Ghana.

. Drug resistance is a major challenge in antibiotic chemotherapy. Assessing resistance profiles of pathogens constitutes an essential surveillance to...

Dec 14 2016 28070190
Persistence of influenza on surfaces.

BACKGROUND: Close contact transmission (either direct or large droplet/droplet nuclei) is considered the main driver of influenza outbreaks but there ...

Dec 13 2016 28139390
Spectral consensus strategy for accurate reconstruction of large biological networks.

BACKGROUND: The last decades witnessed an explosion of large-scale biological datasets whose analyses require the continuous development of innovative...

Dec 13 2016 28105915
Efficacy of tildipirosin metaphylaxis for the prevention of respiratory disease, otitis and mortality in pre-weaned Holstein calves.

The aim of this study was to evaluate the efficacy of two metaphylactic approaches (long acting antibiotic injected once at 10 days of life or twice a...

Dec 12 2016 28093111
A Model-Based Machine Learning Approach to Probing Autonomic Regulation From Nonstationary Vital-Sign Time Series.

Physiological variables, such as heart rate (HR), blood pressure (BP) and respiration (RESP), are tightly regulated and coupled under healthy conditio...

Dec 7 2016 27959829
Improving Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) Treatment Monitoring in South Africa: Evaluation of an Advanced TB/HIV Course for Healthcare Workers.

BACKGROUND: South Africa has dual epidemics of human immunodeficiency virus (HIV) and tuberculosis (TB). Nurse-focused training was combined with onsi...

Dec 7 2016 28480244
Toxoplasma gondii transmission by artificial insemination in sheep with experimentally contaminated frozen semen.

Toxoplasma gondii is a parasite considered one of the major causes of reproductive problems in sheep. Furthermore, the presence of the agent in ram se...

Dec 5 2016 28166964
Human heart failure biomarker immunosensor based on excessively tilted fiber gratings.

A label-free immunosensor platform based on excessively tilted fiber gratings (Ex-TFGs) was developed for highly specific and fast detection of human ...

Dec 5 2016 28101401
Regulatory efficacy of fermented plant extract on the intestinal microflora and lipid profile in mildly hypercholesterolemic individuals.

In recent years, the use of fermented plant products to protect against various metabolic syndromes has been increasing enormously. The objective of t...

Dec 3 2016 28987358
Experimental comparison of point-of-use filters for drinking water ultrafiltration.

BACKGROUND: Waterborne pathogens such as Pseudomonas spp. and Legionella spp. may persist in hospital water networks despite chemical disinfection. Po...

Dec 1 2016 28073586
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