Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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The Risk of Hepatocellular Carcinoma After Directly Acting Antivirals for Hepatitis C Virus Treatment in Liver Transplanted Patients: Is It Real?

INTRODUCTION: Since directly acting antivirals (DAAs) for treatment of hepatitis C virus (HCV) were introduced, conflicting data emerged about the risk of hepatocellular carcinoma (HCC) after interferon (IFN)-free treatments. We present a case of recurrent, extra-hepatic HCC in a liver-transplanted patient soon after successful treatment with DAAs, along with a short review of literature.

Oct 30 2016 28070200

Combining sequence and Gene Ontology for protein module detection in the Weighted Network.

Studies of protein modules in a Protein-Protein Interaction (PPI) network contribute greatly to the understanding of biological mechanisms. With the development of computing science, computational approaches have played an important role in locating protein modules. In this paper, a new approach combining Gene Ontology and amino acid background frequency is introduced to detect the protein modules...

Oct 29 2016 27984079
Wheelchair Navigation System for Disabled and Elderly People.

An intelligent wheelchair (IW) system is developed in order to support safe mobility for disabled or elderly people with various impairments. The prop...

Oct 28 2016 27801852
Procalcitonin as a potential predicting factor for prognosis in bacterial meningitis.

We investigated the potential role of serum procalcitonin in differentiating bacterial meningitis from viral meningitis, and in predicting the prognos...

Oct 26 2016 28341167
Application of bacteriophages during depuration reduces the load of Salmonella Typhimurium in cockles.

As bivalve molluscs are filter feeder, often consumed raw or lightly cooked and are frequently cultivated in contaminated waters, they are implicated ...

Oct 26 2016 29195893
Physicochemical analyses of a bioactive 4-aminoantipyrine analogue - synthesis, crystal structure, solid state interactions, antibacterial, conformational and docking studies.

A novel Schiff base derivative of 4-aminoantipyrine, that is, ()-4-(2-methoxybenzylideneamino)-1,5-dimethyl-2-phenyl-1-pyrazol-3(2)-one (MBA-dMPP), wa...

Oct 26 2016 28096791
Malaria Parasitemia and Parasite Density in Antiretroviral-Treated HIV-Infected Adults Following Discontinuation of Cotrimoxazole Prophylaxis.

BACKGROUND:  Cotrimoxazole (CTX) discontinuation increases malaria incidence in human immunodeficiency virus (HIV)-infected individuals. Rates, quanti...

Oct 25 2016 28077587
Effect of Cav. (Fabaceae) extract on pro-inflammatory enzymes and on planktonic cells and biofilm from Toxicity studies.

Cav. (Fabaceae), a native plant from Argentina has been used traditionally as medicinal species. The aim of the study was to validate the antibiotic ...

Oct 24 2016 30591789
Genotoxic and cytotoxic action potential of Terminalia citrina, a medicinal plant of ethnopharmacological significance.

Most herbal medicines utilized in complementary and alternative medicine lack safety evaluation setting our lives under unwarranted risks. Present stu...

Oct 24 2016 28096789
Multidrug Resistant Causing Prosthetic Valve Endocarditis: A Genetic-Based Chronicle of Evolving Antibiotic Resistance.

 Successful treatment of infections caused by multidrug-resistant (MDR) is thwarted by the emergence of antibiotic resistance and biofilm formation ...

Oct 21 2016 29057280
Accurate classification of brain gliomas by discriminate dictionary learning based on projective dictionary pair learning of proton magnetic resonance spectra.

Proton magnetic resonance spectroscopy is a powerful noninvasive technique that complements the structural images of cMRI, which aids biomedical and c...

Oct 11 2016 27662108
Text mining electronic hospital records to automatically classify admissions against disease: Measuring the impact of linking data sources.

OBJECTIVE: Text and data mining play an important role in obtaining insights from Health and Hospital Information Systems. This paper presents a text ...

Oct 11 2016 27742349
Learning the Relationship between the Primary Structure of HIV Envelope Glycoproteins and Neutralization Activity of Particular Antibodies by Using Artificial Neural Networks.

The dependency between the primary structure of HIV envelope glycoproteins (ENV) and the neutralization data for given antibodies is very complicated ...

Oct 11 2016 27727189
A New Hybrid BFOA-PSO Optimization Technique for Decoupling and Robust Control of Two-Coupled Distillation Column Process.

The two-coupled distillation column process is a physically complicated system in many aspects. Specifically, the nested interrelationship between sys...

Oct 11 2016 27807444
Detecting Essential Proteins Based on Network Topology, Gene Expression Data, and Gene Ontology Information.

The identification of essential proteins in protein-protein interaction (PPI) networks is of great significance for understanding cellular processes. ...

Oct 7 2016 28650821
Achieving partial nitrification by inhibiting the activity of Nitrospira-like bacteria under high-DO conditions in an intermittent aeration reactor.

It is generally accepted that a low dissolved oxygen (DO) concentration is more beneficial for achieving partial nitrification than high-DO. In this s...

Oct 6 2016 28571872
Methanol Extract from Anogeissus leiocarpus (DC) Guill. et Perr. (Combretaceae) Stem Bark Quenches the Quorum Sensing of Pseudomonas aeruginosa PAO1.

Due to its extensive arsenal of virulence factors and inherent resistance to antibiotics, is a threat particularly in immunocompromised patients. Co...

Oct 6 2016 28930136
Symbiont modulates expression of specific gene categories in Angomonas deanei.

Trypanosomatids are parasites that cause disease in humans, animals, and plants. Most are non-pathogenic and some harbor a symbiotic bacterium. Endosy...

Oct 3 2016 27706380
Experimental phage therapy against haematogenous multi-drug resistant pneumonia in mice.

BACKGROUND: Community-acquired haematogenous pneumonia is a rare infection, though it can be acquired nosocomially. Currently, antibiotics used again...

Sep 30 2016 28879116
A novel fuzzy set based multifactor dimensionality reduction method for detecting gene-gene interaction.

BACKGROUND: Gene-gene interaction (GGI) is one of the most popular approaches for finding the missing heritability of common complex traits in genetic...

Sep 29 2016 27765491
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