Gastroenterology

Inflammatory Bowel Disease

Latest AI and machine learning research in inflammatory bowel disease for healthcare professionals.

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Showing 261-280 of 3,673 articles

CAR T-cells in hematologic malignancies: Advances, challenges, and future directions.

Chimeric antigen receptor (CAR) T-cell therapy has transformed the management of hematologic malignancies, achieving high remission rates in relapsed or refractory B-cell acute lymphoblastic leukemia, large B-cell lymphoma, and multiple myeloma. By redirecting autologous or allogeneic T lymphocytes against tumor-associated antigens such as CD19 and TNFRSF17, CAR T-cells overcome resistance to conv...

Mar 4 2026 41940327

A Multiomic Liquid Biopsy for the Earlier Detection of Colorectal Cancer.

UNLABELLED: Timely diagnosis and intervention in colorectal cancer are critical to improving patient outcomes and limiting disease progression. Screening of average-risk individuals is essential for detecting tumors at an earlier, more treatable stage. However, adherence to current screening programs remains suboptimal. Liquid biopsies represent a promising alternative to stool-based tests and may...

Mar 3 2026 41431387
METRON: Metabolic Dynamic Perception Kolmogorov-Arnold Network for Biological Age Estimation.

Biological age provides a more direct reflection of physiological status than chronological age, serving as a vital measure to evaluate health risks a...

Mar 3 2026 41774660
Developing a Metabolic-Associated Prognostic Index for Risk Stratification and Therapeutic Guidance in Stage I Lung Adenocarcinoma via Multiomics Analysis.

PURPOSE: Early-stage lung adenocarcinoma (LUAD) exhibits substantial clinical heterogeneity that is not fully explained by TNM staging, highlighting t...

Mar 2 2026 41771017
A Network-Based Association of IBD and Colorectal Cancer Using Proteomics Data.

BACKGROUND: Colorectal cancer (CRC) is a major cause of morbidity and mortality, with chronic inflammation from inflammatory bowel disease (IBD) repre...

Mar 1 2026 41704020
Artificial Intelligence for Predicting Clinical Outcomes in Interventional Pain Medicine for Spine Disorders: A Systematic Review.

OBJECTIVES: Artificial intelligence (AI) applications are being increasingly explored in pain medicine due to AI's ability to handle multidimensional ...

Mar 1 2026 41728639
Comparative urinary metabolomics reveals unique and shared pathways in COVID-19 and liver diseases.

INTRODUCTION: The COVID-19 pandemic and liver diseases both cause significant metabolic disturbances, yet the specific mechanisms driving these change...

Feb 27 2026 41758429
Computer-Aided Detection-Assisted Colonoscopy Teaches Gaze to Improve Adenoma Detection in First-Year Gastroenterology Fellows.

BACKGROUND AND AIMS: The impact of computer-aided detection (CADe)-assisted colonoscopy on gastroenterology fellow trainees remains incompletely defin...

Feb 26 2026 41767621
Imputation methods for serologic biomarkers in inflammatory bowel disease.

Serologic biomarkers have emerged as a powerful tool for the diagnosis of Inflammatory Bowel Disease (IBD) and the differentiation between subgroups o...

Feb 26 2026 41748696
External Validation of an AI-Based Colonoscopy Quality Assessment Tool in Japanese Clinical Practice: A Pilot Study.

BACKGROUND: While AI-assisted polyp detection has advanced significantly, comprehensive AI-based colonoscopy quality assessment tools remain limited. ...

Feb 25 2026 41739329
A peptide immunomodulator activates MST1 to expand and stabilize murine and human regulatory T cells for immune tolerance.

The expansion and potentiation of regulatory T cells (Treg cells) offer an appealing approach for achieving immune tolerance and controlling overactiv...

Feb 25 2026 41739904
Familial colorectal cancer: risk factors, screening strategies and personalized medicine.

Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, with approximately 25-30 % of cases exhibiting a familial compo...

Feb 23 2026 41771225
Machine learning and metabolic signatures of drowning: A pathway to uncovering cause of death in aquatic environments.

The postmortem diagnosis of drowning is challenging due to the nonspecific and transient nature of classical autopsy findings. This study aimed to inv...

Feb 22 2026 41734481
CT-derived sarcopenia and myosteatosis predict treatment escalation in hospitalized patients with inflammatory Bowel disease.

BACKGROUND: Sarcopenia and myosteatosis reflect muscle quantity and quality and are linked to adverse outcomes in chronic diseases. Their role in pred...

Feb 21 2026 41721866
Noninvasive diagnosis of colorectal adenoma: The emerging potential of blood-based biomarkers.

Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second leading cause of cancer-related death globally. Most CRCs arise fro...

Feb 21 2026 41694494
Optimal management of oligometastatic prostate cancer: current state and future directions.

PURPOSE: Oligometastatic prostate cancer (oligoPCa) represents a clinical state of limited metastatic spread in which metastasis-directed therapy (MDT...

Feb 20 2026 41920569
Immunotherapy in Triple-Negative Breast Cancer: From Molecular Mechanisms to Precision Medicine-Overcoming Resistance and Optimizing Clinical Outcomes.

Triple-negative breast cancer (TNBC) is the most violent type of breast cancer, in which estrogen receptors (ER), progesterone receptors (PR), and hum...

Feb 20 2026 41724338
Machine Learning Prediction of Recurrence in Pediatric Thyroid Cancer: Malignant Endocrine Tumors Cohort Analysis Using XGBoost and SHAP.

CONTEXT: Pediatric differentiated thyroid carcinoma (DTC) often presents with advanced disease but generally has excellent long-term survival. However...

Feb 20 2026 40890050
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