Latest AI and machine learning research in kidney transplantation for healthcare professionals.
BACKGROUND: Acute kidney injury (AKI) is a frequent and serious complication among hospitalized patients, particularly in critical care settings, where its incidence can exceed 50%. AKI is associated with increased mortality, prolonged hospitalization, dialysis dependence, and higher health care costs. Although the KDIGO (Kidney Disease: Improving Global Outcomes) guidelines emphasize supportive c...
Triple-negative breast cancer (TNBC) is classified as an immunologically cold tumor, which markedly weakens the therapeutic efficacy of immune checkpoint blockade (ICB) represented by anti-PD-L1 therapy. To overcome this limitation, an astragalus polysaccharide (APS)-based thermoresponsive hydrogel loaded with a β-elemene (ELE) nanoemulsion (ELE-NE-gel) was developed in this study with the aim of ...
Glioblastoma presents a significant challenge for drug development due to its complex immunosuppressive microenvironment. Identifying candidate therap...
BACKGROUND: Metabolic reprogramming represents a hallmark feature of hepatocellular carcinoma (HCC). As a crucial branch of the polyol pathway, the bi...
BACKGROUND: Hyperphosphatemia is a common complication in hemodialysis and serves as a key marker for evaluating dialysis adequacy. This study aimed t...
INTRODUCTION: Radiographic image quality is evaluated based on technical and anatomical criteria; however, this study investigates how radiographers i...
BACKGROUND: Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a ...
The poor prognosis of high‑grade gliomas, such as glioblastoma, is largely driven by a notably immunosuppressive tumor microenvironment (TME), wherein...
Emerging evidence indicates that aberrant cholesterol metabolism in macrophages plays a role in tumorigenesis, however, how specific metabolites relea...
Oncolytic viruses (OVs) represent a versatile platform for cancer immunotherapy, capable of selectively infecting and lysing tumor cells while trigger...
INTRODUCTION: Timely adjustment of intervention strategies based on multidimensional hemodialysis data is essential for improving patients' quality of...
Mild traumatic brain injury (mTBI) frequently prompts computed tomography (CT) imaging in emergency departments, despite a high proportion of negative...
Tumor heterogeneity remains a major barrier to effective cancer therapy, driving the need for novel biomarkers and targeted strategies. A bibliometric...
AIMS: The increasing prevalence of type 2 diabetes mellitus (T2DM) has led to an increase in diabetic kidney disease (DKD), which is presently a major...
Oral leukoplakia (OLK) is the most common oral potentially malignant disorder and carries a lifetime risk of transformation to oral squamous cell carc...
Mucosal melanoma (MM) is a rare and lethal subtype of melanoma, disproportionately affecting Asian populations and exhibiting distinct clinicopatholog...
The increasing global burden of cancer necessitates innovative therapeutic strategies. Cell therapy represents a major breakthrough in oncology, evolv...
Myeloid cells-including macrophages, monocytes, neutrophils and dendritic cells-are metabolically plastic sentinels that shape the tumor microenvironm...
Mineral and bone disease (MBD) is a frequent complication after solid organ transplantation. The rapid decline in bone mineral density (BMD) during th...
OBJECTIVES: To model the occurrence of adverse events (AEs) among Veterans prescribed nonsteroidal anti-inflammatory drugs (NSAIDs) during emergency d...