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Showing 442-462 of 7,587 articles

Single‑cell mapping of neutrophil extracellular trap signatures in lung adenocarcinoma reveals immune landscapes, prognostic potential, and therapeutic targets.

Neutrophil extracellular traps (NETs) have emerged as key modulators in the tumor microenvironment, ...

Jan 2026 41496413

Deep learning image reconstruction improves 40 keV virtual monoenergetic image quality in rectal cancer.

BACKGROUND: Accurate preoperative evaluation of rectal cancer is essential for staging and treatment...

Jan 2026 41520415

Artificial intelligence in diagnostic, prognostic, and predictive genomic biomarkers for prostate cancer: Ready for prime time?

INTRODUCTION: Until recently, the widespread use of genetic markers in prostate cancer (PCa) has bee...

Jan 2026 41483979

Anomaly detection in gamma-ray spectra using autoencoders with small form factor CZT detectors.

The detection of weak radioactive sources in fluctuating background environments is a critical task ...

Dec 2025 41478139

Unraveling the molecular mechanisms of air pollution-induced lung adenocarcinoma through machine learning, network toxicology, and molecular docking.

OBJECTIVE: Airborne environmental contaminants are established carcinogens. This investigation eluci...

Dec 2025 41478005

Pectin from Phyllanthus emblica L.: Structure elucidation and synergistic in vitro anti-stomach adenocarcinoma effects with 5-fluorouracil.

In recent years, polysaccharides with potential anticancer activity have attracted widespread attent...

Dec 2025 41617283

Diagnostic accuracy of ¹⁸F-FDG PET/CT radiomics for non-invasive prediction of PD-L1 expression in non-small cell lung cancer: A systematic review and meta-analysis.

To evaluate the diagnostic performance, methodological quality, and clinical feasibility of ¹⁸F-FDG ...

Dec 2025 41460438

Causal Inference and Prognostic Modeling in Colorectal Cancer through Integration of Computational Pathology and Mendelian Randomization.

BACKGROUND: While traditional pathology supports the diagnosis and staging of colorectal cancer (CRC...

Dec 2025 41454195

Proteomic Profiling of Plasma Extracellular Vesicles Combined with Multivariate Modeling Identified Potential Biomarkers for Distinguishing Benign Pulmonary Nodules from Early-Stage Lung Adenocarcinoma.

Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer and is difficult to distinguish...

Dec 2025 41452660

Ensemble learning-based radiomics model for predicting radiation-induced temporal lobe injury in nasopharyngeal carcinoma.

PURPOSE: To develop and validate a multimodal ensemble machine learning model integrating multi-sequ...

Dec 2025 41455324

Computed Tomography-Pathology Deep Learning Model for the Precise Prediction of Recurrence in Pathological Stage IA Lung Adenocarcinoma.

BACKGROUND: The postoperative prognosis of pathological stage IA lung adenocarcinoma (LUAD) exhibits...

Dec 2025 41449240

Combining the prognostic values of entropy-based heterogeneity features from 18 F-fluorodeoxyglucose PET and transmission computed tomography using machine learning in patients with lung adenocarcinoma undergoing curative surgery.

OBJECTIVE: The objective of this study is to evaluate the combined prognostic values of 18 F-fluorod...

Dec 2025 41479305

A multicenter multimodel habitat radiomics model for predicting immunotherapy response in advanced NSCLC.

A robust predictive biomarker is critical for identifying patients with NSCLC who may benefit from i...

Dec 2025 41704757

Automated Lymph Node and Extranodal Extension Assessment Improves Risk Stratification in Oropharyngeal Carcinoma.

PURPOSE: Extranodal extension (ENE) is a biomarker in oropharyngeal carcinoma (OPC) but can only be ...

Dec 2025 41435207

Smooth Muscle Disruptive Feature Defines Molecular Subtyping, Risk Stratification, and Metastatic Potential in Prostate Cancer.

BACKGROUND: Smooth muscle (SM) invasion represents a critical feature of prostate cancer (PCa) progr...

Dec 2025 41428021

Relationship between cardiometabolic index and worsening renal function in T2DM: Insights from machine learning, growth mixture modelling, and development of a web-based risk prediction tool.

AIM: Worsening renal function (WRF) is a common and serious complication of type 2 diabetes mellitus...

Dec 2025 41424207

The actual performance of ML/AI models in predicting radiation-induced toxicity in head and neck cancer: a systematic review and meta-analysis.

An increasing number of Artificial intelligence (AI) and machine learning (ML) models are being deve...

Dec 2025 41421773

Bayesian selection of lipidome dynamics features for a K-nearest neighbors (KNN) classifier model of tumor response in patients with advanced gastrointestinal adenocarcinoma undergoing systemic treatment.

BACKGROUND: Dysregulated lipid metabolism is common in patients with gastrointestinal (GI) cancer. T...

Dec 2025 41408017

Amentoflavone from Ginkgo biloba inhibits EMT-driven lung cancer metastasis by targeting TGFBR2: Integrative network pharmacology, machine learning, and experimental validation.

ETHNOPHARMACOLOGICAL RELEVANCE: In non-small cell lung cancer (NSCLC), fatal outcomes predominantly ...

Dec 2025 41412234

Interpretable fusion deep learning on super-resolution MRI for perineural invasion prediction in pancreatic ductal adenocarcinoma: a multicenter study.

PURPOSE: To develop an interpretable fusion deep learning model based on super-resolution (SR) MRI f...

Dec 2025 41418691

Clinical practice, barriers to implementation, and priorities for equitable access of Stereotactic Body Radiation Therapy: An analysis of the global status by the ESTRO SBRT Focus Group.

BACKGROUND: Stereotactic Body Radiation Therapy (SBRT) has become an established treatment for sever...

Dec 2025 41502557