Oncology/Hematology

Lung Cancer

Latest AI and machine learning research in lung cancer for healthcare professionals.

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Integrated multi-omics analyses identified the H3K18la-based spatiotemporal characteristics and risk-stratified treatment strategy in lung adenocarcinoma.

Lung adenocarcinoma (LUAD) is the most common histological type of lung cancer, characterized by high mortality, recurrence, and metastasis. Despite advancements in therapies such as surgery, targeted treatment and immunotherapy, therapeutic resistance and immune evasion remain significant challenges. In our study, we integrated multi-omics data, including spatial transcriptomics, single-cell RNA ...

Nov 20 2025 41274397

Accuracy of Photon Dose Calculation on Photon-Counting Computed Tomography-A Comparison Study Based on Virtual Monoenergetic and Electron Density (Rho) Images for Pancreatic Cases.

PURPOSE: Photon-counting computed tomography (PCCT) offers versatile anatomic information because of better energy discrimination and higher spatial resolution than conventional energy-integrating computed tomography (CT). With its rapid applications in diagnostic imaging, its potential within radiation oncology remains largely unexplored. Successful radiation therapy (RT) relies on both high-qual...

Nov 19 2025 41541756
Total-body [18F]FDG-PET/CT imaging of healthy volunteers with minimal effective dose.

PURPOSE: High-sensitivity, total-body (TB) positron emission tomography (PET) and computed tomography (CT) imaging systems enable substantial reductio...

Nov 18 2025 41251746
Hopfield neural networks with diverse activation functions: impact of variable action gradients and electromagnetic radiation effects.

Activation functions and their variable gradient action are pivotal in bridging artificial neural networks with the dynamic behavior of biological neu...

Nov 17 2025 41319405
Novel growth pattern-specific digital marker of TILs improves stratification of lung adenocarcinoma patients.

Lung adenocarcinoma (LUAD) is one of the most prevalent forms of cancer and continues to be associated with high mortality rates, despite recent advan...

Nov 15 2025 41240064
Emerging trends in nuclear medicine: breakthrough in radiopharmaceuticals, Geant4 simulations, and AI integration.

Nuclear medicine has witnessed revolutionary progress, spurred by advances in radiopharmaceuticals, computational modeling, and artificial intelligenc...

Nov 14 2025 41237411
Noninvasive follicular thyroid neoplasm with papillary-like nuclear features: an update.

PURPOSE OF REVIEW: Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) has been recognized as a diagnostic entity sin...

Nov 10 2025 41213591
Automatic segmentation and CT-based deep learning radiomics nomogram for predicting overall survival in patients with small cell lung cancer: A multicenter cohort study.

BACKGROUND AND OBJECTIVE: Accurate prediction of overall survival (OS) in patients with small cell lung cancer (SCLC) is crucial for personalized trea...

Nov 10 2025 41252869
The Impact of Radiation Dose to Bowel on the Risk of Developing Gastrointestinal Toxicities When Treating Abdominopelvic Soft-Tissue Sarcomas With Preoperative Radiation Therapy.

PURPOSE: Abdominopelvic soft-tissue sarcomas (AP-STS) are selectively treated with radiation therapy (RT) followed by surgery. We investigated dosimet...

Nov 9 2025 41492444
Automatically Measuring Kidney, Liver, and Cyst Volumes in Autosomal Dominant Polycystic Kidney Disease.

KEY POINTS: TraceOrg is a web-based tool that automatically labels kidney, liver, and cysts, reporting volumes and Mayo Imaging Classification. Extern...

Nov 4 2025 41186985
Genetic Determinants and Breeding Strategies for Rice Cooking and Eating Quality: A Comprehensive Review.

Rice cooking and eating quality (CEQ), a core agronomic trait tied to consumer preference and market value, is regulated by endosperm starch, protein,...

Nov 4 2025 41186968
Multiperspective tumor heterogeneity metrics for preoperative prediction of IASLC grading in clinical stage IA lung adenocarcinomas: A multicenter study.

BACKGROUND AND OBJECTIVE: Accurate preoperative prediction of the International Association for the Study of Lung Cancer (IASLC) grades is crucial for...

Nov 4 2025 41197251
Malignant pleural mesothelioma classification and survival prediction with CT imaging using ResNet.

OBJECTIVES: This study aims to achieve accurate differentiation of malignant pleural mesothelioma (MPM) from metastatic pleural disease (MPD) and to p...

Oct 30 2025 41168494
Machine learning-based integration develops a lactate metabolism related gene signature for improving outcomes in pancreatic ductal adenocarcinoma.

OBJECTIVES: Given its high global mortality rate, pancreatic ductal adenocarcinoma (PDAC) remains a significant area of investigation. However, a robu...

Oct 28 2025 41161133
NHOC/NHOP as novel biomarkers for predicting lymph node metastasis in NSCLC using PET/CT radiomics and machine learning: a two-center retrospective study.

PURPOSE: NHOC and NHOP, defined as the normalized distances from peak uptake to tumour centroid and perimeter, are novel PET/CT metrics of tumour aggr...

Oct 25 2025 41137928
Apparent Diffusion Coefficient Magnetic Resonance Imaging as a Predictive Biomarker for Hypoxia, Treatment De-escalation, and Recurrence in Human Papillomavirus-Associated Oropharyngeal Cancer.

PURPOSE: To evaluate whether quantitative diffusion-weighted magnetic resonance imaging derived apparent diffusion coefficient (ADC) parametric values...

Oct 23 2025 41138786
A Five-Plasma Protein-Based Algorithm for Predicting Incident CKD in Type 2 Diabetes.

KEY POINTS: Proteomics analyses consistently identified nine independent protein predictors for CKD in both Chinese and European participants with typ...

Oct 20 2025 41563825
Multi-stage dual-domain progressive network with synergistic training for sparse-view CT reconstruction.

Sparse-view computed tomography (SVCT) significantly reduces patient radiation exposure and accelerates data acquisition by using fewer projections fo...

Oct 18 2025 41151529
Astroimmunology: the effects of spaceflight and its associated stressors on the immune system.

As humans embark on longer and deeper missions into space, it is crucial to understand how spaceflight impacts the immune system. Decades of discoveri...

Oct 16 2025 41102553
Predictive prioritization of enhancers associated with pancreatic disease risk.

Genetic and epigenetic variation in enhancers is associated with disease susceptibility; however, linking enhancers to target genes and predicting enh...

Oct 16 2025 41106391
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