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Rapid Detection From Clinical Mastitis Milk by Colloidal Gold Nanoparticle-Based Immunochromatographic Strips.

Rapid diagnostic technologies for bovine mastitis caused by () are urgently needed. In the current study, we generated an anti-ribosomal protein-L7/L12 antibody to detect and an anti-ribosomal protein-L7/L12 antibody-coated immune-chromatographic strip (ICS) test. Moreover, we determined the ability of the ICS test to detect from milk samples collected from cows with clinical mastitis. The deve...

Anti-toxoplasma, antioxidant and cytotoxic activities of (Fée) T. Moore hexane fraction.

The apicomplexan parasite () causes toxoplasmosis in humans. Pyrimethamine and sulfadiazine that are the drugs of choice to treat the disease, produce severe side effects as well as failure treatments because of drug resistance; thus, novel anti-Toxoplasma compounds are needed and natural compounds can be a good source to obtain them, as medicinal plants have been used to control other apicomplex...

Comparison of the predictive outcomes for anti-tuberculosis drug-induced hepatotoxicity by different machine learning techniques.

BACKGROUND: The study compared the predictive outcomes of artificial neural network, support vector machine and random forest on the occurrence of ant...

Membranous Nephropathy with Rapid Progression.

We report a 49-year-old man with microscopic hematuria, subnephrotic proteinuria, and rapidly progressive renal failure. His biopsy had features of Ph...

Antimicrobial, anti-cancer, anti-filarial and anti-inflammatory activities of Cowabenzophenone A extracted from the endophytic fungus isolated from a mangrove plant .

Cowabenzophenone A was isolated from an endophytic fungus Aspergillus terreus isolated from a mangrove plant Bruguiera gymnorrhyza. The structure was ...

Discovery of potential 1,3,5-Triazine compounds against strains of Plasmodium falciparum using supervised machine learning models.

The Malaria burden was an escalating global encumbrance and need to be addressed with critical care. Anti-malarial drug discovery was integrated with ...

Efficient identification of novel anti-glioma lead compounds by machine learning models.

Glioblastoma multiforme (GBM) is the most devastating and widespread primary central nervous system tumor. Pharmacological treatment of this malignanc...

Crocin exerts improving effects on indomethacin-induced small intestinal ulcer by antioxidant, anti-inflammatory and anti-apoptotic mechanisms.

Crocin is a plant-derived carotenoid and bears potent antioxidant property. Ranitidine (a histamine H receptor blocker) is used for peptic ulcer treat...

Effect of experimental infectious bursal disease virus on clinical signs and pathogenesis of avian influenza virus HN in turkey by real time PCR.

Infectious bursal disease virus (IBDV) in turkeys may result in immunosuppression, and inability of turkeys to resist nonpathogenic or less pathogenic...

Toxicity and Anti-promastigote Activity of Benzoxazinoid Analogs Against and .

Here, we aim to evaluate the antileishmanial activity of compounds with a benzoxazinoid (BX) skeleton, previously synthesized by our group, against ...

Synthesis and biological characterization of MnZnEuDyFeO nanoparticles by sonochemical approach.

Metallic nanoparticles (NPs) possess unique properties which makes them attractive candidates for various applications especially in field of experime...

Action mechanism of anti-wrinkle effect of methanol extract in human dermal fibroblast and keratinocyte cell lines.

is a deciduous broad-leaf bush and endemic species widely found in Korea. Recently, we reported that methanol extract (RYME) had excellent antioxida...

A new isoflavonol and other constituents from Cameroonian propolis and evaluation of their anti-inflammatory, antifungal and antioxidant potential.

Propolis is rich in diverse bioactive compounds. Propolis samples were collected from three localities of Cameroon and used in the study. Column chrom...

Interaction of apigenin-7-O-glucoside with pyrimethamine against growth.

Apigenin-7-O-glucoside, a flavonoid glucoside known to inhibit cancer cell growth, fungi growth, both intra and extracellular reactive oxygen species ...

A Low-Cost Nanomaterial-based Electrochemical Immunosensor on Paper for High-Sensitivity Early Detection of Pancreatic Cancer.

Due to the lack of specific early detection methods for pancreatic cancer, it usually goes undetected until it is advanced. By employing paper-based e...

Finite-time and fixed-time anti-synchronization of Markovian neural networks with stochastic disturbances via switching control.

This paper proposes a unified theoretical framework to study the problem of finite/fixed-time drive-response anti-synchronization for a class of Marko...

An agent-based lattice model for the emergence of anti-microbial resistance.

This work introduces a new probabilistic agent-based lattice model for studying the emergence of anti-microbial resistance (AMR) and proposes a new pr...

Synthesis and Hypoglycemic and Anti-inflammatory Activity Screening of Novel Substituted 5-[Morpholino(Phenyl)Methyl]-Thiazolidine-2,4-Diones and Their Molecular Docking Studies.

OBJECTIVES: The aim was the synthesis of novel substituted 5-[morpholino(phenyl)methyl]-thiazolidine-2,4-diones and screening for their hypoglycemic ...

Ultrasensitive Anti-Interference Voice Recognition by Bio-Inspired Skin-Attachable Self-Cleaning Acoustic Sensors.

Human voice recognition systems (VRSs) are a prerequisite for voice-controlled human-machine interfaces (HMIs). In order to avoid interference from un...

Machine Learning to Predict Anti-Tumor Necrosis Factor Drug Responses of Rheumatoid Arthritis Patients by Integrating Clinical and Genetic Markers.

OBJECTIVE: Accurate prediction of treatment responses in rheumatoid arthritis (RA) patients can provide valuable information on effective drug selecti...