Rheumatology

Lupus

Latest AI and machine learning research in lupus for healthcare professionals.

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Showing 821-840 of 1,738 articles

A novel triterpenoid 16-hydroxy betulinic acid isolated from attributes multi-faced pharmacological activities.

The aerial parts of extensively used ethnomedicinal plant (Burm. f.) Robinson growing wild in Bangladesh were investigated to isolate and characterize compounds responsible for the bioactivities of the plant. In the present study, a new derivatives of betulinic acid, 16-hydroxy betulinic acid [3β,16-dihydroxy-lup-20(29)-en-28-oic] was isolated and the structure of the compound was determined by N...

Mar 6 2018 30899171

New Treatment for Urethral Rent in Stallions.

The aim of this report is to describe a new methodology to successfully treat stallions diagnosed with urethral rent. Four stallions of ages ranging from 7 to 12 years (median 9) with hemospermia were admitted for clinical evaluation, breeding soundness examination, and urethroscopy for inspection of the urethra and vesicular glands. Once the presence of urethral rent was identified and/or other s...

Feb 20 2018 30973159
Lipid Metabolism in Patients with Anti-N-Methyl-D-Aspartate Receptor Encephalitis.

OBJECTIVE: Lipid metabolism has been implicated in autoimmune disorders, but its relationship with anti-N-methyl-D-aspartate receptor (anti-NMDAR) enc...

Feb 1 2018 29393234
anti-inflammatory and skin protective properties of Virgin coconut oil.

Virgin coconut oil (VCO) has been traditionally used as moisturizer since centuries by people in the tropical region. Clinical studies have revealed t...

Jan 17 2018 30671361
A method of gene expression data transfer from cell lines to cancer patients for machine-learning prediction of drug efficiency.

Personalized medicine implies that distinct treatment methods are prescribed to individual patients according several features that may be obtained fr...

Jan 17 2018 29251172
Anti-Obesity Property of Lichen Extract in 3T3-L1 Cells and Diet-Induced Obese Mice.

(TV) is an edible lichen that is prevalent in the alpine zone of East Asia. This study evaluated the feasibility of using TV acetone extracts as a fu...

Dec 31 2017 29333380
Analysis of Antioxidant and Anti-Inflammatory Activities of Solvent Fractions from Cultivated with Mycelium.

In this study, the crude ethanol cultivated with mycelium (RNGM) extract was solvent fractionated with organic solvents such as -hexane, chloroform,...

Dec 31 2017 29333391
Plant-Based Beverages as Good Sources of Free and Glycosidic Plant Sterols.

To address the ever-growing group of health-conscious consumers, more and more nutritional and health claims are being used on food products. Neverthe...

Dec 29 2017 29286348
Development of an immunochromatographic strip incorporating anti-mitragynine monoclonal antibody conjugated to colloidal gold for kratom alkaloids detection.

A lateral flow-based immunochromatographic strip was developed for the rapid detection of mitragynine (MG), a dominant alkaloid found in the leaves of...

Dec 29 2017 29287305
Essential oil of Citrus lumia Risso: Phytochemical profile, antioxidant properties and activity on the central nervous system.

The use of essential oils (EOs) is known since long time in traditional medicine and aromatherapy for the management of various oxidative stress-relat...

Dec 28 2017 29288755
Specialized oxygenated heterocyclics from Villorita cyprinoides with cyclooxygenase-2 and 5-lipoxygenase inhibitory properties.

Villorita cyprinoides is traditional seafood in the coastal regions of Arabian Sea. Bioactivity-guided purification of ethyl acetate:methanol extract ...

Dec 28 2017 29579915
Investigation of nepetolide as a novel lead compound: Antioxidant, antimicrobial, cytotoxic, anticancer, anti-inflammatory, analgesic activities and molecular docking evaluation.

In the present study, we describe various pharmacological effects and computational analysis of nepetolide, a tricyclic clerodane-type diterpene, isol...

Dec 28 2017 29556134
Quantification and pharmacokinetics of alpinetin in rat plasma by UHPLC-MS/MS using protein precipitation coupled with dilution approach to eliminate matrix effects.

Alpinetin, a bioactive flavonoid, has attracted great attention due to its diverse therapeutic effects, namely anti-oxidant, anti-tumor and anti-infla...

Dec 27 2017 29433096
Peanut testa extracts possessing histone deacetylase inhibitory activity induce apoptosis in cholangiocarcinoma cells.

Previous studies demonstrated that peanut testa extracts (KK4 and ICG15042) containing natural histone deacetylase (HDAC) inhibitors inhibited the gro...

Dec 27 2017 29268244
Jobelyn attenuates inflammatory responses and neurobehavioural deficits associated with complete Freund-adjuvant-induced arthritis in mice.

Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects the physical and psychosocial wellbeing of the patients and a major cause of ...

Dec 27 2017 29288974
Anti-Müllerian Hormone (AMH), antral follicle count (AFC), external morphometrics and fertility in Tabapuã cows.

The intense selection of characteristics related to animal performance may affect the reproductive efficiency of beef cows negatively. Selection for f...

Dec 24 2017 29279199
Anti-Myeloperoxidase Antibodies Associate with Future Proliferative Lupus Nephritis.

BACKGROUND: The subclinical pathophysiology of proliferative lupus nephritis (PLN) has not been fully elucidated. Myeloperoxidase anti-neutrophil cyto...

Dec 24 2017 29435367
Design, synthesis and bioactivities of phenithionate analogues or derivatives for anti-schistosomiasis.

A novel series of phenithionate analogues or derivatives were designed and synthesized using phenithionate as the lead compound, and their bioactiviti...

Dec 22 2017 30108926
Morroniside on anti-inflammation activities in rats following acute myocardial infarction.

Our previous studies have confirmed that morroniside has neuroprotective effects. However, the effects of morroniside on cardiac myocardium remain unk...

Dec 22 2017 29302208
"Hypothyroidism screening during first trimester of pregnancy".

BACKGROUND: Subclinical hypothyroidism is defined as an elevated thyroid-stimulating hormone level with a normal thyroxin level without signs or sympt...

Dec 22 2017 29273014
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